Displaying drugs 4376 - 4400 of 11307 in total
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Description: … ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human ... Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified …
BIIB021
BIIB021 has been investigated for the treatment of Tumors and Lymphoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Indatuximab ravtansine
Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Investigational
Zanolimumab
Zanolimumab is a fully human monoclonal antibody directed against CD4.
Investigational
Matched Description: … Zanolimumab is a fully human monoclonal antibody directed against CD4. …
Becatecarin
Becatecarin is a derivative of rebeccamycin.
Investigational
Matched Description: … Becatecarin is a derivative of [rebeccamycin]. …
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Description: … of heat shock protein 90 (HSP90). ... Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Retaspimycin
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Spanlecortemlocel
Investigational
LY-2090314
Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Iupac: … piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen-3-yl]-4-{imidazo[1,2-a] …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Description: … of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD …
CDD-0102
Investigational
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
Matched Description: … It is widely used as a sugar substitute and in "sugar-free" food products. ... Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many ... Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Troxacitabine
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Investigational
Matched Description: … Troxacitabine is a nucleoside analog with antineoplastic activity. …
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
Vepsitamab
Investigational
XL-888
XL888 has been used in trials studying the treatment of Cancer and Melanoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Description: … Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination …
7-Hydroxystaurosporine
Experimental
Investigational
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
CDX-1135
CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex). It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage.
Investigational
Matched Description: … CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed …
CDX-6210
CDX-6210 is a modified version of a leucine decarboxylase enzyme from Planctomycetaceae bacterium.
Investigational
Matched Description: … CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_. …
CDX-6512
CDX-6512 is a modified, gastrointestinal-stable bacterial leucine decarboxylase. Developed by Codexis, it is being investigated for the treatment of homocystinuria And Maple Syrup Urine Disease.[L46651, L46656]
Investigational
Matched Description: … CDX-6512 is a modified, gastrointestinal-stable bacterial leucine decarboxylase. …
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses …
Lemzoparlimab
Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Displaying drugs 4376 - 4400 of 11307 in total