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Displaying drugs 4501 - 4525 of 11558 in total

Brofaromine

Experimental
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Picolinic acid

PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Description: … As a therapeutic agent, the molecule works by binding to zinc finger proteins (ZFPs) in a way that changes ... PCL-016 plays a key role in zinc transport. ... PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Benzquinamide

Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Withdrawn
Matched Iupac: … 3-(diethylcarbamoyl)-9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl acetate …
Matched Description: … Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative …

Gluco-Phenylimidazole

Experimental
Matched Iupac: … (5R,6R,7S,8S)-5-(hydroxymethyl)-2-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …

TRIAZOLOPYRIMIDINE

Experimental
Matched Iupac: … 7-(3-bromophenyl)-5-{[(pyridin-4-yl)methyl]amino}-3H-4lambda5-[1,2,4]triazolo[1,5-a]pyrimidin-4-ylium …

AT-7519

AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Description: … AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression …

APG-1387

APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B).
Investigational
Matched Iupac: … ,10aR)-8-[(diphenylmethyl)carbamoyl]-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a] ... }benzenesulfonyl)-N-(diphenylmethyl)-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a] …
Matched Description: … APG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination …

Cerulenin

Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Description: … In sterol synthesis, inhibits HMG-CoA synthetase activity. …

Oxothiazolidinecarboxylic acid

Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational

Cephalosporin C

Experimental

ET140203

Investigational

METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE

Experimental

N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid

N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.
Experimental
Matched Description: … These are compounds comprising a purine base attached to a sugar. ... N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. …

1-Amino-1-Carbonyl Pentane

Experimental

Lysine Nz-Carboxylic Acid

Experimental

2-Hydroxyethyl Disulfide

Experimental

Triethyl phosphate

Experimental

Valpromide

Experimental

Iproniazid

Withdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Withdrawn
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Isoflavone

Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Description: … Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important ... benefits of consuming soy proteins and isoflavones [A33099], the trials investigating isoflavone as a ... have been studied and demonstrated for many years, with some evidence of soy products associated with a …

Propyl Gallate

Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
Investigational
Matched Description: … Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Succinimide

Experimental

Ritanserin

Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Investigational
Matched Iupac: … 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin …

Retagliptin

Retagliptin is under investigation in clinical trial NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients).
Investigational
Matched Iupac: … methyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,5-a] …

Cilazaprilat

Experimental
Matched Iupac: … (1S,9S)-9-{[(1S)-1-carboxy-3-phenylpropyl]amino}-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine- …
Displaying drugs 4501 - 4525 of 11558 in total