Displaying drugs 15226 - 15250 of 15294 in total
Pevonedistat
Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Investigational
Matched Iupac: … [(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl …
Matched Description: … Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma …
Matched Description: … Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma …
Verinurad
Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.
Investigational
Matched Iupac: … 2-{[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]sulfanyl}-2-methylpropanoic acid …
Matched Description: … Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia …
Matched Description: … Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia …
Lesogaberan
Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Investigational
Matched Iupac: … [(2R)-3-amino-2-fluoropropyl]phosphinic acid …
Matched Description: … Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn …
Matched Categories: … GABA-A Receptor Agonists …
Matched Description: … Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn …
Matched Categories: … GABA-A Receptor Agonists …
GSK-1059615
GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.
Investigational
Matched Description: … GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer …
JNJ-40411813
JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.
Investigational
Matched Iupac: … 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)-1,2-dihydropyridin-2-one …
Matched Description: … JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia …
Matched Description: … JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia …
PF-03715455
PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-1-({2-[(3-{2-[(2-hydroxyethyl)sulfanyl] ... phenyl}-[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]phenyl}methyl)urea …
Matched Description: … PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tradipitant
Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis, Chronic Pruritus, and Atopic Dermatitis, among others.
Investigational
Matched Iupac: … 2-(1-{[3,5-bis(trifluoromethyl)phenyl]methyl}-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)-3-(2-chlorobenzoyl …
Matched Description: … Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis …
Matched Description: … Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis …
Pyroxamide
Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Investigational
Matched Iupac: … N-hydroxy-N'-(pyridin-3-yl)octanediamide …
Matched Description: … Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer …
Matched Description: … Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer …
Tripterygium wilfordii whole
Tripterygium wilfordii whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Tripterygium wilfordii whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Lirilumab
Lirilumab has been used in trials studying the treatment of Leukemia, CANCER,NOS, Multiple Myeloma, Lymphocytic Leukemia, and Acute Myeloid Leukemia, among others.
Investigational
Matched Description: … Lirilumab has been used in trials studying the treatment of Leukemia, CANCER,NOS, Multiple Myeloma, Lymphocytic …
Preladenant
Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement Disorders, Antipsychotic Agents, and Parkinsonian Disorders, among others.
Investigational
Matched Iupac: … 4-(furan-2-yl)-10-(2-{4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl}ethyl)-3,5,6,8,10,11-hexaazatricyclo …
Matched Description: … Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement …
Matched Description: … Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement …
Vadastuximab talirine
Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia.
Investigational
Matched Description: … Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Galunisertib
Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid Tumor, GLIOBLASTOMA, and Prostate Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide …
Matched Description: … Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lorvotuzumab mertansine
Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
Investigational
Matched Description: … Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer …
Ganitumab
Ganitumab has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, Breast Cancer, Breast Tumors, and Breast Neoplasms, among others.
Investigational
Matched Description: … Ganitumab has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, Breast Cancer …
Sofinicline
Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies, Diabetic Polyneuropathy, and Diabetic Neuropathic Pain, among others.
Investigational
Matched Iupac: … (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane …
Matched Description: … Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies …
Matched Description: … Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies …
VM4-037
VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).
Investigational
Matched Iupac: … (2S)-3-[4-(2-fluoroethoxy)phenyl]-2-[(2S)-3-methyl-2-(4-{[(2-sulfamoyl-1,3-benzothiazol-6-yl)oxy]methyl …
Matched Description: … , Non-Randomized Study of [F-18]VM4-037). ... VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center …
Matched Description: … , Non-Randomized Study of [F-18]VM4-037). ... VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center …
MK-1454
A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB)...
Investigational
Matched Description: … This results in a CTL-mediated immune response against tumor cells and causes tumor cell lysis. ... kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB) and interferon regulatory factor 3 ... (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory …
ZYCOV-D
The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India . The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest . Once the plasmid DNA is introduced into host cells and the viral protein is translated,...
Investigational
Matched Description: … The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid ... As of August, 2020 the candidate is in Phase II clinical trials[A219758]. ... The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758]. …
Buparlisib
Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2,6-bis(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine …
Matched Description: … Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Description: … Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Peficitinib
Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Investigational
Matched Iupac: … 4-{[(1R,2s,3S,5r)-5-hydroxyadamantan-2-yl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide …
Matched Description: … Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics …
Matched Description: … Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics …
Ralimetinib
Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2-tert-butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin- ... 2-amine …
Matched Description: … Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult …
Matched Description: … Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult …
Broxuridine
Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
Investigational
Matched Iupac: … 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage …
Matched Description: … Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage …
Netazepide
Netazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia, Barrett's Esophagus, ECL-cell Hyperplasia, and Rebound Hyperacidity, among others.
Investigational
Matched Iupac: … 3-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1-[ ... 3-(methylamino)phenyl]urea …
Matched Description: … Netazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Netazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
TU-100
TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others.
Investigational
Matched Iupac: … 20-methyl-20-azapentacyclo[10.7.1.0^{2,11}.0^{4,9}.0^{13,18}]icosa-2(11),4,6,8,13,15,17-heptaene-3,10,19 …
Matched Description: … TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease …
Matched Description: … TU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease …
Displaying drugs 15226 - 15250 of 15294 in total