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Displaying drugs 551 - 575 of 647 in total
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Calciumacetat Medice 500 mg - Filmtabletten ... Calciumacetat Medice 700 mg - Filmtabletten …
Investigational
Matched Synonyms: … -chain, dimer ... -chain, dimer ... Immunoglobulin g1, anti-(hepatitis b virus surface antigen) (human monoclonal pe1-1 .gamma.1-chain), …
Investigational
Matched Synonyms: … -chain, dimer ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IMMUNOGLOBULIN LIGHT CHAIN AMYLOID (AL) FIBRILS), CHIMERIC ... MONOCLONAL ANTIBODY (GAMMA1 HEAVY CHAIN CHIMERIC (1-441) (MUS MUSCULUS VH (IGHV2-3*01 (92.6%)-(IGHD) …
Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).
Investigational
Matched Synonyms: … -chain, dimer tetrakis(thioether) with vedotin ... Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide …
Investigational
Matched Synonyms: … -chain, dimer ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma.1-chain
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … -chain, dimer ... Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … -CHAIN, DIMER ... C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -chain, dimer ... anti-(human tumor necrosis factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse ... monoclonal c242 light chain, dimer, compound with n(sup 2')-deacetyl-n(sup 2')-(3-mercapto-1-oxopropyl ... monoclonal c242 light chain, dimer, compound with n(sup 2')-deacetyl-n(sup 2')-(3-mercapto-1-oxopropyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -chain, dimer ... -chain, dimer ... evelyn-rockitniki-abelseth glycoprotein ectodomain epitope g-iii) (mus musculus monoclonal .gamma.2-chain
Investigational
Matched Synonyms: … -chain, dimer ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma.1-chain
Investigational
Matched Synonyms: … -chain, dimer ... Immunoglobulin g1, anti-(hepatitis b surface antigen) (human monoclonal gc1102 .gamma.1-chain), disulfide …
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … ), disulfide with human monoclonal ttac-0001 light chain, dimer ... Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac-0001 heavy chain
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … monoclonal SRF388 κ-chain, dimer ... G1-kappa, anti-[IL27 (interleukin 27,IL27p28, IL27A)], Homo sapiens monoclonal antibody,gamma1 heavy chain ... Immunoglobulin G1, anti-(human interleukin 27) (human monoclonal SRF388 γ1-chain), disulfide with human …
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … -chain, dimer ... proline,432-alanine), anti-(human programmed cell death 1) (human-mus musculus monoclonal hx008 .gamma.4-chain
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Investigational
Matched Synonyms: … Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7) …
Atlantic mackerel allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Fish, mackerel, atlantic, raw …
Matched Mixtures name: … Fish Mix …
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Synonyms: … Two-chain urokinase …
Matched Description: … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and ... [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … -CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL AB79 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN ... HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL CYCLASE, ANTIGENE CD38))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … -chain, dimer ... respiratory syncytial virus fusion glycoprotein f0 (protein f))human monoclonal antibody.gamma.1 heavy chain ... Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897 .gamma.1-chain
Matched Description: … neutralizes several RSV A and B strains. ... antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and ... the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry process, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … -CHAIN, (223->217')(2 ... -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ... IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL …
Matched Description: … an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure ... immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … -chain, dimer ... Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1-chain
Matched Description: … Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO ... 450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL BA301 .GAMMA.1-CHAIN
Displaying drugs 551 - 575 of 647 in total