Displaying drugs 6476 - 6500 of 8033 in total
Ciglitazone
Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market....
Experimental
Matched Description: … Ciglitazone is a potent and selective PPARγ ligand with an EC50 of 3.0 µM. ... Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones ... Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to …
MYR-101
MYR-101 (rAAV-Olig001-ASPA) is a recombinant adeno-associated virus (rAAV) vector-based gene therapy intended to treat Canavan disease. Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain. It is caused by a mutation in the aspartoacylase gene (ASPA), which leads to a deficiency of the...
Investigational
Matched Description: … ASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA). ... granted MYR-101 Fast Track, Rare Pediatric Disease (RPD), and Orphan Drug designations for the treatment of ... It is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Description: … Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth ... [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and ... BTK receptors, abivertinib exerts immunomodulatory effects by preventing the production and release of …
alpha-methylthiofentanyl
alpha-methylthiofentanyl is an opioid analgesic that is an analog of fentanyl.
Illicit
Matched Description: … alpha-methylthiofentanyl is an opioid analgesic that is an analog of fentanyl. …
Cadaverine
Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
Experimental
Matched Description: … Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. …
Resatorvid
Resatorvid is an investigational compound designed for the treatment of severe sepsis.
Investigational
Matched Description: … Resatorvid is an investigational compound designed for the treatment of severe sepsis. …
Talviraline
Talviraline has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Description: … Talviraline has been used in trials studying the treatment of HIV Infections. …
Emivirine
Emivirine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Description: … Emivirine has been used in trials studying the treatment of HIV Infections. …
Acediasulfone
Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Experimental
Matched Description: … Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone. …
Pyridoxamine
Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Description: … Pyridoxamine has been used in trials studying the treatment of Kidney Stones. …
UK-390957
UK-390,957 has been used in trials studying the treatment of Ejaculation.
Investigational
Matched Description: … UK-390,957 has been used in trials studying the treatment of Ejaculation. …
Linerixibat
GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Description: … GSK2330672 has been investigated for the treatment of Diabetes Mellitus, Type 2. …
Talinolol
Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
Investigational
Matched Description: … Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. …
BMS-903452
BMS-903452 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Description: … BMS-903452 has been used in trials studying the treatment of Diabetes. …
Hyodeoxycholic Acid
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
Investigational
Matched Description: … Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia. …
Dusquetide
Dusquetide has been used in trials studying the treatment of Oral Mucositis.
Investigational
Matched Description: … Dusquetide has been used in trials studying the treatment of Oral Mucositis. …
Pridopidine
Pridopidine has been used in trials studying the treatment of Huntington's Disease.
Investigational
Matched Description: … Pridopidine has been used in trials studying the treatment of Huntington's Disease. …
Dapaconazole
Dapaconazole has been used in trials studying the treatment of Tinea Pedis.
Investigational
Matched Description: … Dapaconazole has been used in trials studying the treatment of Tinea Pedis. …
GSK-2018682
GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Description: … GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting. …
Telinavir
Telinavir has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Description: … Telinavir has been used in trials studying the treatment of HIV Infections. …
Atevirdine
Atevirdine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Description: … Atevirdine has been used in trials studying the treatment of HIV Infections. …
Losmapimod
Losmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Description: … Losmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease. …
Rostafuroxin
Rostafuroxin has been used in trials studying the treatment of Essential Hypertension.
Investigational
Matched Description: … Rostafuroxin has been used in trials studying the treatment of Essential Hypertension. …
Galeterone
Galeterone has been used in trials studying the treatment of Prostate Cancer.
Investigational
Matched Description: … Galeterone has been used in trials studying the treatment of Prostate Cancer. …
Chlorine dioxide
Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Description: … Chlorine Dioxide has been used in trials studying the treatment of Halitosis. …
Displaying drugs 6476 - 6500 of 8033 in total