Displaying drugs 651 - 675 of 711 in total
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Synonyms: … migration inhibitory factor, glycosylation-inhibiting factor, glif, gif)), homo sapiens monoclonal antibody …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
NBL-015
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 ... SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Agrostis gigantea top
Agrostis gigantea top is the flowering part of the Agrostis gigantea plant. Agrostis gigantea top is mainly used in allergenic testing.
Approved
Matched Synonyms: … Vilfa alba top …
Pyridostigmine
Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and fatigue. Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the...
Approved
Investigational
Matched International brands: … Antilon …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Dezamizumab
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … recombinant monoclonal antibody to human serum amyloid P component ... AMYLOID P COMPONENT SERUM, SERUM AMYLOID P COMPONENT, SAP, PENTRAXIN-2, PTX2)), HUMANIZED MONOCLONAL ANTIBODY …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zalifrelimab
Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Synonyms: … A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4) …
Amatuximab
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Chimeric monoclonal antibody to mesothelin …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody ... receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody ch14.18 ... CHIMERIC ANTI-DISIALOGANGLIOSIDE (GD2) MONOCLONAL ANTIBODY (CH14.18/CHO) …
Matched Description: … By binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the ... constant regions of human IgG1 heavy-chain and kappa light-chain. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Matched Description: … By binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the ... constant regions of human IgG1 heavy-chain and kappa light-chain. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb ... XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …
Crovalimab
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Matched Synonyms: … Complement c5 inhibitory humanized recycling monoclonal antibody (rg-6107 ) …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Begelomab
Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … COMPLEXING PROTEIN 2, ADCP2, TP103, T CELL ACTIVATION ANTIGEN CD26, CD26)), MUS MUSCULUS MONOCLONAL ANTIBODY …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
KITE-222
Investigational
Matched Synonyms: … An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived …
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … ANTI-CD30/CD16A MONOCLONAL ANTIBODY AFM13 ... tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ibandronate
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol ... Musculo-Skeletal System …
Matched Products: … IPEXAL …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol ... Musculo-Skeletal System …
Matched Products: … IPEXAL …
Befovacimab
Investigational
Matched Synonyms: … Human tissue factor pathway inhibitor-neutralizing antibody (bay 1093884) …
Zimberelimab
Investigational
Matched Synonyms: … Anti-pd-1 monoclonal antibody gls-010 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anselamimab
Investigational
Matched Synonyms: … Chimeric fibril reactive monoclonal antibody 11-1F4 ... G1-KAPPA, ANTI-(HOMO SAPIENS IMMUNOGLOBULIN LIGHT CHAIN AMYLOID (AL) FIBRILS), CHIMERIC MONOCLONAL ANTIBODY …
Metelimumab
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Human anti-transforming growth factor beta 1 monoclonal antibody …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta …
Chamomile
Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Chamomilla Vulgaris Flower …
Displaying drugs 651 - 675 of 711 in total