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Displaying drugs 51 - 65 of 65 in total

Phenothrin

Experimental
Matched Categories: … Synthetic Compounds ... Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Cannabinor

Cannabinor, a synthetic CB2-selective agonist, is in Phase 2 clinical testing as an analgesic.
Investigational
Matched Description: … Cannabinor, a synthetic CB2-selective agonist, is in Phase 2 clinical testing as an analgesic. …

Chlorotoxin I-131

Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates functioning of the chloride channels on cell membranes. Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain...
Investigational
Matched Description: … The synthetic version of this peptide has been manufactured and covalently linked to iodine 131 as a ... Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates ... It is a synthetic version of a neurotoxin isolated from the venom of the Giant Yellow Israeli scorpion …

Gabexate

Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. It also known to decrease production of inflammatory cytokines. Gabexate has been investigated for use in cancer, ischemia-reperfusion injury, and pancreatitis.[A19218,A19219,A19220]
Investigational
Matched Description: … Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. ... Gabexate has been investigated for use in cancer, ischemia-reperfusion injury, and pancreatitis. …

Tiropramide

Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
Investigational
Matched Description: … of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome). ... Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety …
Matched Categories: … Synthetic Antispasmodics, Amides With Tertiary Amines ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Prinomastat

Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier.
Investigational
Matched Description: … Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity. ... extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis ... Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing …

Fenretinide

A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Investigational
Matched Description: … A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at …

Vapreotide

Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Description: … Vapreotide is a synthetic octapeptide somatostatin analog. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Camostat

Camostat mesylate, or FOY-305, is a synthetic serine protease inhibitor.[A193842,A193848] It was first described in the literature in 1981, as part of research on the inhibition of skin tumors in mice. Camostat mesylate inhibits cholecystokinin, pro-inflammatory cytokines, and serine proteases, leading to it being investigated for multiple indications including the...
Experimental
Matched Description: … Camostat mesylate, or FOY-305, is a synthetic serine protease inhibitor. ... [A198807] Camostat mesylate inhibits cholecystokinin, pro-inflammatory cytokines, and serine proteases …
Matched Categories: … Blood and Blood Forming Organs …

Otilonium

Experimental
Investigational
Matched Categories: … Synthetic Anticholinergics, Quaternary Ammonium Compounds ... Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... otilonium bromide and psycholeptics …

Ularitide

Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is ... involved in regulating blood pressure and the excretion of water and sodium from the kidneys. ... Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

AS-8112

AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Description: … AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes ... D2 and D3, and the serotonin receptor 5-HT3. ... It has been shown to exert potent antiemetic effects in animal studies and has been investigated for …

Etretinate

Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid. The mechanism of action of etretinate is still incompletely understood although, like retinoic acid, it is thought to interfere with the terminal differentiation of keratinocytes. It is thought to bind to the retinoic acid receptors....
Withdrawn
Matched Description: … It is a synthetic aromatic retinoid. ... Etretinate was taken off the market in Canada in 1996 and America in 1998 due to the risk of birth defects …

Nonivamide

Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) . Nonivamide is a flavoring ingredient. Nonivamide is an...
Investigational
Matched Description: … It is naturally found in chili peppers but manufactured to produce a synthetic form for various pharmacologic ... Nonivamide is an organic compound and a capsaicinoid. ... It is an amide of pelargonic acid and _vanillylamine_. …

Obinepitide

Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Displaying drugs 51 - 65 of 65 in total