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Displaying drugs 51 - 75 of 106 in total
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta (recombinant) …
Matched Description: … [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and ... (MS), and was initially approved by the FDA in 1992. ... significantly debilitating with a profound impact on the quality of life. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ... IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders …
Matched Categories: … Antigen Neutralization ... Amino Acids, Peptides, and Proteins …
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint ... [A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture ... ,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Matched Description: … by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. ... IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment ... and promote programmed cell death [A31578]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B virus vaccine, B-Massachusetts-2-2012-like virus, recombinant
Matched Name: … Influenza B virus B/Massachusetts/2/2012 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B virus vaccine, B-Wisconsin-1-2010-like virus …
Matched Name: … Influenza B virus B/Wisconsin/1/2010 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Recombinant influenza vaccines …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza A virus vaccine, A-Texas-50-2012 X-223A (H3N2), Inactivated …
Matched Name: … Influenza A virus A/Texas/50/2012 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Recombinant influenza vaccines …
Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Name: … Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
Matched Description: … Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine ... and one from subfamily B (A05 and B01, respectively). ... It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 (H1N1) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hawaii/70/2019 (H1N1) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 52 L1 protein …
Matched Name: … Human papillomavirus type 52 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 52 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 31 L1 protein …
Matched Name: … Human papillomavirus type 31 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 31 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 45. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 45 L1 protein …
Matched Name: … Human papillomavirus type 45 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 45 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … Recombinant human papillomavirus type 18 L1 protein …
Matched Name: … Human papillomavirus type 18 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A Virus A/Sydney/5/2021 SAN-013 (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (UV, formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Synonyms: … AD26.COV2.S [RECOMBINANT] …
Matched Description: … 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. ... The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype ... A preclinical study in hamsters infected with SARS-COV-2 infection[A220053] showed a single immunization …
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Synonyms: … IdeS recombinant
Matched Description: … Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant ... [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions ... [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... a single inbakicept is complexed with two nogapendekin alfa components. ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
Approved
Investigational
Withdrawn
Matched Description: … -3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. ... fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins ... Recombinant Fusion Proteins ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 51 - 75 of 106 in total