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Displaying drugs 876 - 900 of 3133 in total
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Salts name: … Rabeprazole sodium
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and metronidazole ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … PARIET TABLET 5MG ... RABELIS DDR 50 MG KAPSÜL, 28 ADET ... Rabeprazole sodium
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and
Matched Salts name: … Ibandronate sodium
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Ibandronate Sodium ... Ibandronate sodium ... IBACUR 50 MG ŞASE, 56 ADET …
Investigational
Matched Synonyms: … L-serine, 2,3-bis((1-oxo-9-octadecenyl)oxy)propyl hydrogen phosphate (ester), (r-(z,z))- ... )oxy)-, 5-oxide, (2s,8r,19z)- ... 4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-(((9z)-1-oxo-9-octadecen-1-yl …
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … 3-(Methylcarbamoyl)pyridine ... 3-(N-Methylcarbamoyl)pyridine
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. ... levels and prevent cardiovascular disease. ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol …
Matched Salts cas: … 93957-55-2 …
Matched Salts name: … Fluvastatin sodium
Matched Products: … Fluvastatin Sodium ... Fluvastatin Sodium ER …
Experimental
Matched Name: … 5-(1-Carboxy-1-Phosphonooxy-Ethoxyl)-Shikimate-3-Phosphate
Matched Iupac: … (3R,4S,5R)-5-[(1S)-1-carboxy-1-(phosphonooxy)ethoxy]-4-hydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic …
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Synonyms: … 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione ... (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. ... safer and more effective alternatives for patients with type 2 diabetes mellitus. …
Matched Mixtures name: … Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone and Metformin Hydrocholride ... Pioglitazone Hydrochloride and Metformin Hydrochloride
Matched Salts name: … Pioglitazone hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Products: … Pioglitazone Hydrochloride ... PIOGLITAZONE HYDROCHLORIDE
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine
Matched Iupac: … methyl pyridine-3-carboxylate …
Matched Description: … muscle and joint pains [F64]. ... an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and ... methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Iupac: … -dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)-5- …
Matched Description: … renal fluid reuptake by acting through V1 and V2 cellular receptors. ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …
Experimental
Matched Name: … N-Bromoacetyl-Aminoethyl Phosphate
Experimental
Matched Name: … L-Threonohydroxamate 4-Phosphate
Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired Glucose Tolerance.
Investigational
Matched Name: … Quercetin-3'-O-phosphate
Matched Iupac: … [2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]phosphonic acid …
Matched Description: … Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired …
Investigational
Matched Name: … Glyceraldehyde-3-Phosphate Dehydrogenase …
Matched Categories: … Enzymes and Coenzymes ... Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …
Experimental
Matched Name: … 2-Amino-Vinyl-Phosphate
Experimental
Matched Name: … Indole-3-Propanol Phosphate
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Experimental
Matched Name: … Nicotinamide adenine dinucleotide phosphate
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl …
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... the 5'-phosphate adenosine 2',5'-bisphosphate. ... A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Indole-3-Glycerol Phosphate
Matched Categories: … Indicators and Reagents ... Sugar Phosphates
Experimental
Matched Name: … DIETHYL 4-METHOXYPHENYL PHOSPHATE
Matched Iupac: … diethyl 4-methoxyphenyl phosphate
Experimental
Matched Synonyms: … Pantetheine-4'-phosphate
Matched Name: … D-pantetheine 4'-phosphate
PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
Investigational
Matched Synonyms: … 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Matched Name: … 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Matched Description: … PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science …
Experimental
Matched Name: … Mercaptomethyl Phosphonate
Matched Iupac: … (sulfanylmethyl)phosphonate
Experimental
Matched Name: … Methionine Phosphinate
Experimental
Matched Name: … Norleucine Phosphonate
Experimental
Matched Name: … Methionine Phosphonate
Displaying drugs 876 - 900 of 3133 in total