Displaying drugs 101 - 106 of 106 in total
GI-5005
GI-5005 is GlobeImmune's lead infectious disease product from its proprietary Tarmogen active immunotherapy platform for the treatment of chronic hepatitis C infection. GI-5005 is whole, heat-killed recombinant yeast genetically modified to express HCV-specific protein targets. Tarmogens are believed to activate both an innate immune response via Toll-like receptors (TLRs), as...
Investigational
Matched Description: … GI-5005 is whole, heat-killed recombinant yeast genetically modified to express HCV-specific protein ... to activate both an innate immune response via Toll-like receptors (TLRs), as well as an adaptive, antigen …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Hu-rhEGF-rP64k/Mont
Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the treatment of advanced non-small cell lung cancer (NSCLC).
Investigational
Matched Description: … Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically ... conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... ], where a single inbakicept is complexed with two nogapendekin alfa components. ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Zastumotide
Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R. It is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Description: … Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known ... clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and …
AG-858
AG-858 (autologous heat-shock protein 70 peptide vaccine) is
a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity...
Investigational
Matched Description: … AG-858 (autologous heat-shock protein 70 peptide vaccine) is
a recombinant cancer vaccine made with ... HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing ... Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and …
MVA-BN-brachyury-TRICOM vaccine
MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1...
Investigational
Matched Description: … ), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad ... It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN ... [L44513] MVA-BN-brachyury-TRICOM vaccine is administered as a priming vaccine, followed by the administration …
Displaying drugs 101 - 106 of 106 in total