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Displaying drugs 2051 - 2075 of 2876 in total
Experimental
Matched Name: … 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
Matched Iupac: … (2R,3R,4S,5R,6S)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid
Experimental
Matched Name: … (10R)-10-formyl-5,8,10-trideazafolic acid
Matched Iupac: … ({4-[(1R)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic acid
Experimental
Matched Name: … Benzo[B]Thiophene-2-Boronic Acid
Matched Iupac: … (1-benzothiophen-2-yl)boronic acid
Experimental
Matched Name: … (2R)-2-benzyl-3-nitropropanoic acid
Matched Iupac: … (2R)-2-benzyl-3-nitropropanoic acid
Experimental
Matched Name: … 3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID
Matched Iupac: … 3',5'-difluoro-[1,1'-biphenyl]-4-carboxylic acid
Experimental
Matched Name: … 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID
Matched Iupac: … 4-[(cyclohexylcarbamoyl)amino]butanoic acid
Experimental
Matched Name: … 6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID
Matched Iupac: … 6-[(cyclohexylcarbamoyl)amino]hexanoic acid
Experimental
Matched Name: … 7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID
Matched Iupac: … 7-[(cyclohexylcarbamoyl)amino]heptanoic acid
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … BELLEX CREMA 1% …
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Iupac: … dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents ... Antiparasitic Products, Insecticides and Repellents …
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid
Matched Iupac: … (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. ... A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. …
Investigational
Matched Synonyms: … 5-(3,5-Dimethyl-4-hydroxybenzylamino)-3-(4-morpholin-4-yl-phenylamino)-1H-pyrazole-4-carboxylic acid
Experimental
Matched Name: … (4e)-4-Aminohex-4-Enoic Acid
Matched Iupac: … (4E)-4-aminohex-4-enoic acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-Amino Benzoic Acid
Matched Iupac: … 3-amino-4-acetamidobenzoic acid
Experimental
Matched Name: … 5-Mercapto-2-Nitro-Benzoic Acid
Matched Iupac: … 2-nitro-5-sulfanylbenzoic acid
Experimental
Matched Name: … 2-Anhydro-3-Fluoro-Quinic Acid
Matched Iupac: … (1R,4S,5R)-3-fluoro-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid
Experimental
Matched Name: … 3-Fluoro-2-(Phosphonooxy)Propanoic Acid
Matched Iupac: … (2R)-3-fluoro-2-(phosphonooxy)propanoic acid
Experimental
Matched Name: … 4-Methyl-Pyrroline-5-Carboxylic Acid
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid
Experimental
Matched Name: … 3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid
Displaying drugs 2051 - 2075 of 2876 in total