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Displaying drugs 4951 - 4975 of 11848 in total
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Investigational
Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Experimental
Matched Iupac: … (1S,3aS,3bS,11aS)-1-acetyl-1,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency …
Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and a polar group at...
Experimental
Matched Description: … a polar group at each end. ... It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and ... Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Iupac: … 1R,3aS,3bR,9bS,11aS)-5',5',11a-trimethyl-6'-oxo-2,3,3a,3b,4,5,9b,10,11,11a-decahydrospiro[cyclopenta[a] …
2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol.
Experimental
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7,8 …
Matched Description: … It is also a positional isomer of estriol. [A31630] …
Canrenone has been used in trials studying the diagnostic of Heart Failure.
Investigational
Matched Iupac: … 1R,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-2,3,3a,3b,7,8,9,9a,9b,10,11,11a-dodecahydrospiro[cyclopenta[a] …
Fluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients).
Investigational
Matched Iupac: … 4-({4-fluoro-3-[2-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl}methyl …
Matched Description: … Fluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With …
Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD).
Investigational
Matched Iupac: … {2-[(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H,3H,4H,6H,7H-pyrimido[4,3-a]isoquinolin …
Matched Description: … Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate …
Investigational
Matched Iupac: … 7-methyl-2-({7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl}amino)-9-(oxan-4-yl)-8,9-dihydro-7H-purin-8- …
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Description: … A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate …
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem]
Experimental
Matched Description: … A noncompetitive antagonist at GABA-A receptors and thus a convulsant. ... Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote …
Matched Categories: … GABA-A Receptor Antagonists ... Compounds used in a research, industrial, or household setting …
Experimental
Cobolimab is under investigation in clinical trial NCT04655976 (Study of Cobolimab in Combination With Dostarlimab and Docetaxel in Advanced NSCLC Participants).
Investigational
GRAd-COV2 is a COVID-19 vaccine candidate being developed by ReiThera[L30420, L30423]. This therapy is based on a novel replication-incompetent simian adenoviral vector that encodes the full-length SARS-CoV-2 spike protein (GRAd-COV2)[L30420, L30423]. Preclinical and clinical studies show GRAd-COV2 to induce robust cellular and humoral immune responses .
Investigational
Matched Description: … GRAd-COV2 is a COVID-19 vaccine candidate being developed by ReiThera[L30420, L30423]. ... This therapy is based on a novel replication-incompetent simian adenoviral vector that encodes the full-length …
Experimental
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion Pharmaceuticals.
Investigational
Matched Description: … Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion …
Matched Categories: … Endothelin A Receptor Antagonists …
Amber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Amber is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.
Investigational
Matched Description: … Biomed 101 is a solid. …
Enbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Investigational
Matched Categories: … GABA-A Receptor Agonists …
Displaying drugs 4951 - 4975 of 11848 in total