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Displaying drugs 776 - 800 of 838 in total
Experimental
Matched Name: … 3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid …
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid …
P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Investigational
Matched Synonyms: … Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T …
Matched Description: … P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology. …
Experimental
Matched Name: … 3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium …
Matched Iupac: … [(2R)-3-carboxy-2-(octanoyloxy)propyl]trimethylazanium …
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Experimental
Matched Name: … 3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine …
Investigational
Matched Synonyms: … (2'R,3'S)-2'-hydroxy-N-carboxy-3'-amino-5'-methyl-hexanoic,N-tert-butyl ester, 13 ester 5B-20-epoxy-1B …
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester …
Matched Description: … fluid and electrolyte homeostasis. ... Ultimately, enalaprilat works to reduce blood pressure and blood fluid volume. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and
Matched Mixtures name: … Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... enalapril and diuretics ... enalapril and nitrendipine ... enalapril and lercanidipine …
CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting B-cell maturation antigen …
Matched Description: … CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell …
Experimental
Matched Name: … 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID …
Matched Iupac: … 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-3-yl)benzoic acid …
Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine ... Angiotensin II receptor blockers (ARBs) and diuretics …
Matched Products: … CARDOL
Experimental
Matched Name: … 1(R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID …
Experimental
Matched Name: … Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane …
Matched Iupac: … 5-({[2-({[(2-carboxy-2-methyl-1,3-dioxan-5-yl)oxy]carbonyl}amino)ethyl]carbamoyl}oxy)-2-methyl-1,3-dioxane …
Experimental
Matched Name: … (2E)-2-({(2S)-2-CARBOXY-2-[(PHENOXYACETYL)AMINO]ETHOXY}IMINO)PENTANEDIOIC ACID …
Matched Iupac: … (2E)-2-{[(2S)-2-carboxy-2-(2-phenoxyacetamido)ethoxy]imino}pentanedioic acid …
MB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
Investigational
Matched Name: … MB-102 CD123 CAR
Matched Description: … genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and
Experimental
Matched Name: … N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid …
Matched Description: … It is sold under the name "Colazal" in the US and "Colazide" in the UK. …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Synonyms: … (S)-5-amino-5-carboxy-N,N,N-trimethyl-1-pentanaminium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID …
Matched Iupac: … 2-[(1R)-1-carboxy-2-(4-hydroxyphenyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid …
Experimental
Matched Name: … [(3R,7R)-3,7,11,15-tetramethylhexadecyl]oxy}propyl (2R)-2-hydroxy-3-[(hydroxyphosphinato)oxy]propyl phosphate
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Experimental
Matched Name: … 1-[4-Carboxy-2-(3-Pentylamino)Phenyl]-5,5'-Di(Hydroxymethyl)Pyrrolidin-2-One …
Experimental
Matched Synonyms: … 2-Carboxy-4'-(dimethylamino)azobenzene …
Experimental
Matched Name: … 3-[(1-Amino-2-Carboxy-Ethyl)-Hydroxy-Phosphinoyl]-2-Methyl-Propionic Acid …
Displaying drugs 776 - 800 of 838 in total