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Displaying drugs 776 - 800 of 897 in total
DU125530 is under investigation in clinical trial NCT01119430 (Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder).
Investigational
Matched Iupac: … 2-{4-[4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]butyl}-2,3-dihydro-1lambda6,2-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
123I-iodometomidate is under investigation in clinical trial NCT00454103 (Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy).
Investigational
Matched Iupac: … methyl 1-[(1R)-1-(4-iodophenyl)ethyl]-1H-imidazole-5-carboxylate …
Experimental
Investigational
Matched Iupac: … 12-methyl-7-thia-2,4,5-triazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),3,5,8,10-pentaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Experimental
Investigational
1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Experimental
Matched Synonyms: … Dodecan-1-ol …
Matched Name: … 1-Dodecanol …
Matched Iupac: … dodecan-1-ol …
Matched Description: … 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. ... It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. ... (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) …
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan DB00762, a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative...
Investigational
Matched Iupac: … 10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Description: … the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and ... 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan ... [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. …
Investigational
Matched Iupac: … {10,13}.1^{17,21}.0^{4,9}]hentriaconta-1(27),2(31),4(9),5,7,10,12,17(29),18,20,24(28),25-dodecaene-16,22,22 ... 18-fluoro-25-methoxy-31-methyl-3,22lambda6,30-trithia-6,8,15,23,26-pentaazahexacyclo[22.3.1.1^{2,5}.1^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid …
Matched Iupac: … (5E)-7-[(1S,5Z)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid …
Experimental
Matched Synonyms: … 18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper(1+ …
Matched Iupac: … [16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-21-ide ... lambda1-copper(1+) 4,20-bis(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo …
Mipsagargin has been used in trials studying the treatment of Prostate Cancer, Prostatic Neoplasms, Advanced Solid Tumors, Glioblastoma Multiforme, and Hepatocellular Carcinoma, among others.
Investigational
Matched Iupac: … (2S)-2-[(4S)-4-[(4S)-4-[(4S)-4-[(2S)-3-[(12-{[(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-3,3a-dihydroxy ... methylbut-2-enoyl]oxy}-7-(octanoyloxy)-2-oxo-2H,3H,3aH,4H,5H,6H,6aH,7H,8H,9bH-azuleno[4,5-b]furan-4-yl]oxy}-12
Matched Description: … treatment of Prostate Cancer, Prostatic Neoplasms, Advanced Solid Tumors, Glioblastoma Multiforme, and
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory...
Investigational
Matched Description: … 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. ... A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin ... Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Picropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.
Investigational
Matched Iupac: … 10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12
Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations . It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage . The UV-filter substance, sulisobenzone (BP-4) is widely...
Experimental
Matched Synonyms: … 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid …
Matched Iupac: … 5-benzoyl-4-hydroxy-2-methoxybenzene-1-sulfonic acid …
Matched Description: … As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and ... The benzophenones are a group of aromatic ketones that have both pharmaceutical and industrial applications ... pharmaceuticals and as an additive for plastics, coatings, and adhesives [L2670]. …
Matched Salts cas: … 6628-37-1
Matched Mixtures name: … Sunscreen SPF 12 ... 3-IN-1 Active Moisturizer …
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Iupac: … N-{3-[(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl …
Matched Description: … Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth ... may provide more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin ... In binding to and inhibiting EGFR and BTK receptors, abivertinib exerts immunomodulatory effects by preventing …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … 2β,4a-dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic acid, 1,4a-lactone …
Matched Iupac: … (1R,2R,5R,8R,9S,10R,11S,12S)-12-hydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1^{5,8} …
This solid compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. This substance targets the protein interleukin-2.
Experimental
Matched Synonyms: … Methyl N-{[(3R)-1-carbamimidoyl-3-piperidinyl]acetyl}-4-(phenylethynyl)-L-phenylalaninate …
Matched Name: … Methyl (2S)-2-[[2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetyl]amino]-3-[4-(2-phenylethynyl)phenyl]propanoate …
Matched Iupac: … methyl (2S)-2-{2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetamido}-3-[4-(2-phenylethynyl)phenyl]propanoate …
Matched Description: … This substance targets the protein interleukin-2. ... These are organic compounds containing a 1,2-diphenylethylene moiety. ... The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. …
Rimtuzalcap is a novel modulator of small-conductance calcium-activated potassium channels that is under investigation for the treatment of essential tremor.
Investigational
Matched Synonyms: … N-(4,4-difluorocyclohexyl)-2-(3-methyl-1H-pyrazol-1-yl)-6-morpholinopyrimidin-4-amine …
Matched Iupac: … N-(4,4-difluorocyclohexyl)-2-(3-methyl-1H-pyrazol-1-yl)-6-(morpholin-4-yl)pyrimidin-4-amine …
Matched Description: … Rimtuzalcap is a novel modulator of small-conductance calcium-activated potassium channels that is under …
Investigational
Matched Iupac: … -ethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Aramchol has been used in trials studying the treatment of HIV, Gallstones, Fatty Liver, Metabolic Syndrome, and Nonalcoholic Steatohepatitis, among others.
Investigational
Matched Description: … has been used in trials studying the treatment of HIV, Gallstones, Fatty Liver, Metabolic Syndrome, and
Matched Categories: … Bile Acids and Salts …
Relacorilant is under investigation in clinical trial NCT02804750 (Study to Evaluate CORT125134 in Patients With Cushing's Syndrome).
Investigational
Matched Iupac: … 2-[(4aR)-1-(4-fluorophenyl)-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-1H,4H,4aH,5H,6H,7H,8H-pyrido[3,4-f …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 776 - 800 of 897 in total