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Displaying drugs 826 - 850 of 897 in total
Pyroquilon
Pyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene reductase active site.
Experimental
Matched Iupac: … 1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one …
Matched Description: … Pyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Pyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Azapropazone
Withdrawn
Matched Synonyms: … 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione …
Matched Iupac: … (4S)-7-(dimethylamino)-12-methyl-4-(prop-2-en-1-yl)-2,6,8-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13), …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … (4S)-7-(dimethylamino)-12-methyl-4-(prop-2-en-1-yl)-2,6,8-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13), …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Esuberaprost
Investigational
Matched Synonyms: … (+)-4-((1r,2r,3as,8bs)-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro ... methyl-1-octen-6-ynyl)-, (1r,2r,3as,8bs)- ... -1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid …
Matched Iupac: … {2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid ... 4-[(2S,3R,4R,6S)-4-hydroxy-3-[(1E,3S,4S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^ …
Matched Iupac: … {2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid ... 4-[(2S,3R,4R,6S)-4-hydroxy-3-[(1E,3S,4S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^ …
Immunocytokine NHS-IL12
Investigational
(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine
Experimental
Matched Name: … (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine …
Matched Iupac: … -methanesulfonyl-11-(2,4,5-trifluorophenyl)-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8-tetraen-12 …
Matched Iupac: … -methanesulfonyl-11-(2,4,5-trifluorophenyl)-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8-tetraen-12 …
Motuporin
Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey.
Experimental
Matched Iupac: … (2Z,5R,6S,9S,12S,13S,16R)-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien ... -1-yl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-9-(propan-2-yl)-1,4,8,11,15-pentaazacyclononadecane-5,16 …
Matched Description: … Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron
Experimental
Matched Iupac: … 12-(4-carboxybutyl)-2,2-difluoro-4-octyl-1lambda5,3-diaza-2-boratricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10 ... -pentaen-1-ylium-2-uide …
(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one
Experimental
Matched Name: … (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one …
Matched Iupac: … (12R)-12-(aminomethyl)-4-methoxy-8-thia-11,14-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),3,5-tetraen …
Matched Iupac: … (12R)-12-(aminomethyl)-4-methoxy-8-thia-11,14-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),3,5-tetraen …
Doxofylline
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … with significantly fewer side effects in animal and human studies. ... Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. ... contrast with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 …
TH-9402 free base
Investigational
Zinc mesoporphyrin
Investigational
Matched Synonyms: … tetramethyl-21h,23h-porphine-2,18-dipropanoato(4-)-.kappa.n21,.kappa.n22,.kappa.n23,.kappa.n24)-, hydrogen (1: …
Matched Iupac: … {8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide ... (2-carboxyethyl)-14,19-diethyl-4,10,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … {8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide ... (2-carboxyethyl)-14,19-diethyl-4,10,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rubitecan
Investigational
Matched Iupac: … -19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
2-(3-BROMOPHENYL)-6-[(2-HYDROXYETHYL)AMINO]-1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONE
Experimental
Matched Iupac: … 3-(3-bromophenyl)-8-[(2-hydroxyethyl)amino]-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(12),5,7,9(13),10-pentaene …
(13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25),18,20-HEPTAENE-23,26-DIONE
Experimental
Matched Name: … 13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1( …
Matched Iupac: … heptacosa-1(24),2(7),3,5,17,19,21(25)-heptaene-23,27-dione ... (13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahexacyclo[15.6.2.1^{6,9}.1^{12,15}.0^{2,7}.0^{21,25}] …
Matched Iupac: … heptacosa-1(24),2(7),3,5,17,19,21(25)-heptaene-23,27-dione ... (13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahexacyclo[15.6.2.1^{6,9}.1^{12,15}.0^{2,7}.0^{21,25}] …
alpha-Conotoxin VC 1.1
Investigational
Matched Synonyms: … ACV-1 …
Matched Iupac: … 7,10,13,19,22,25,28,31,34,37,43,46,49,51-tetradecaazatetracyclo[31.17.7.0^{15,19}.0^{39,43}]heptapentacontan-12 …
Matched Iupac: … 7,10,13,19,22,25,28,31,34,37,43,46,49,51-tetradecaazatetracyclo[31.17.7.0^{15,19}.0^{39,43}]heptapentacontan-12 …
(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine
Experimental
Matched Name: … (7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine …
Matched Iupac: … (11R,12R)-11-(2,4,5-trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8-tetraen-12 …
Matched Iupac: … (11R,12R)-11-(2,4,5-trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8-tetraen-12 …
Inavolisib
Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer).
Investigational
Matched Iupac: … 14),2,4,10,12-pentaen-12-yl}amino)propanamide ... [(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^{2,6}]tetradeca-1( …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ESK981
Investigational
Matched Synonyms: … -8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1) ... 4h-indazolo(5,4-a)pyrrolo(3,4-c)carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl) …
Matched Iupac: … 16),2(10),4(9),5,7,11(15),17,20-octaen-14-one; 4-methylbenzene-1-sulfonic acid ... pyrimidin-2-yl)amino]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1( …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 16),2(10),4(9),5,7,11(15),17,20-octaen-14-one; 4-methylbenzene-1-sulfonic acid ... pyrimidin-2-yl)amino]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1( …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Azapentacene
Experimental
SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL) ESTER
Experimental
Matched Name: … SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A] …
Matched Iupac: … phenanthren-1-yl]oxy}-4-oxobutanoic acid ... ,3bR,9aR,9bS,11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Iupac: … phenanthren-1-yl]oxy}-4-oxobutanoic acid ... ,3bR,9aR,9bS,11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE
Experimental
Matched Iupac: … 7-chloro-11,17-dioxa-2,4,20,22-tetraazatricyclo[16.3.1.0^{5,10}]docosa-1(22),5(10),6,8,18,20-hexaen-3 …
7-carboxy-5-hydroxy-12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole
Experimental
Matched Name: … 7-carboxy-5-hydroxy-12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole …
Matched Iupac: … 9),5,7,11,14,17(22),18,20-decaene-12-carboxylic acid ... 14-hydroxy-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4( …
Matched Iupac: … 9),5,7,11,14,17(22),18,20-decaene-12-carboxylic acid ... 14-hydroxy-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4( …
Calanolide A
Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs are being developed by Sarawak Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared...
Investigational
Matched Synonyms: … (+)-calanolide A …
Matched Name: … Calanolide A …
Matched Iupac: … (10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-6,10,11,12-tetrahydro-2H-1,5,9-trioxatriphenylen …
Matched Description: … Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found ... A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared ... A related compound, calanolide B, also has anti-HIV activity. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Name: … Calanolide A …
Matched Iupac: … (10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-6,10,11,12-tetrahydro-2H-1,5,9-trioxatriphenylen …
Matched Description: … Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found ... A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared ... A related compound, calanolide B, also has anti-HIV activity. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 826 - 850 of 897 in total