Displaying drugs 12351 - 12375 of 15144 in total
PF-03758309
PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Investigational
Tiracizine
Experimental
Stannsoporfin
Stannsoporfin is a competitive heme oxygenase (HO) inhibitor being developed by InfaCare, a subsidiary of WellSpring Pharmaceuticals, for the prevention of hyperbilirubinemia in infants at risk of developing jaundice.
Investigational
INCB13739
INCB13739 is developed as a new treatment for type 2 diabetes.
It is an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of type 2 diabetes.
Investigational
TP-508
TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Investigational
Amibegron
Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Investigational
Biomed 101
Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.
Investigational
Matched Description: … Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma …
Mirostipen
Investigational
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and …
AS1409
AS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and...
Investigational
Matched Description: … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma …
KD3010
KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
LAX-101
LAX-101 treats hungtington’s disease, not just the symptoms but the disease itself. The active molecule in LAX-101 is Eicosapentaenoic Acid (EPA). All molecules of EPA are identical. The molecules of EPA found in LAX-101 are identical to the molecules of EPA found in fish oil food supplements.
Investigational
VTP-201227
VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications. It is being developed by Vitae Pharmaceuticals.
Investigational
Matched Description: … VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment …
ALKS 29
ALKS 29 is a new product candidate for the treatment of alcohol dependence. It is being developed by Alkermes, Inc.
Investigational
PF-03187207
PF-03187207 is a nitric oxide-donating prostaglandin F2-alpha analogs for the potential treatment of glaucoma. Based on the very promising preclinical results and on the well-known activities of nitric oxide, PF-03187207 is expected to have an increased capacity to reduce high IOP. The development of abnormally high IOP, due to blockage...
Investigational
Matched Description: … Based on the very promising preclinical results and on the well-known activities of nitric oxide, PF- …
Norclozapine
ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia. It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today.
Investigational
Matched Description: … ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA …
LLL-3348
The botanical drug product LLL-3348 is a once-daily oral formulation for treatment of chronic stable plaque type psoriasis.
Investigational
TG1024
Investigational
Manitimus
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Description: … FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Amperozide
Amperozide is a diphenylbutylpiperazine atypical antipsychotic which antagonizes 5-HT2A receptors. It inhibits dopamine release and alters the firing of dopaminergic neurons. Investigations regarding the use of the agent revolved primarily around its capability for treating schizophrenia in humans even though the drug was ultimately never clinically adopted for this indication....
Experimental
Matched Description: … It inhibits dopamine release and alters the firing of dopaminergic neurons. ... amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and …
N-Allylaniline
Experimental
2-Propyl-Aniline
Experimental
3,4-dimethylaniline
Experimental
Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins
Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. Lipoaspiration, also...
Investigational
Matched Description: … This is followed by purification and expansion of the cells in vitro. ... Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and ... multipotent, with the capability of forming different tissues, some of which include bone, muscle, neural, and …
Displaying drugs 12351 - 12375 of 15144 in total