Displaying drugs 1351 - 1375 of 1467 in total
FB-825
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment of human …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin …
AAV2/8.TBG.hARSB
Investigational
Matched Synonyms: … serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of the human …
L-Dilinoleoyllecithin
Experimental
Matched Synonyms: … (2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate …
Arcitumomab
Investigational
Matched Synonyms: … -chain anti-human antigen cea), disulfide with mouse monoclonal immu-4 light chain ... -chain anti-human antigen cea), disulphide with mouse monoclonal immu-4 light chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cosfroviximab
Investigational
Matched Synonyms: … musculus monoclonal c13c6-fr1 heavy chain), disulfide with human-mus musculus monoclonal c13c6-fr1 . ... Immunoglobulin g1, anti-(ebolavirus/reston ebolavirus/sudan ebolavirus/tai forest ebolavirus glycoprotein) (human-mus …
Anselamimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human amyloid fibril) (human-mus musculus monoclonal cael-101 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal cael-101 .kappa. …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
AVR-RD-04
AVR-RD-04 is an investigational gene therapy for cystinosis. It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.
Investigational
Matched Synonyms: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
Matched Description: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
Matched Description: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Experimental
Matched Name: … 2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Belzupacap Sarotalocan
Investigational
Matched Synonyms: … Human papillomavirus virus-like particles conjugated with ir700 dye au-011 …
L-3972-T
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Magrolimab
Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal hu5f9-g4 .kappa. …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Iluzanebart
Investigational
Matched Synonyms: … on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain ... Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed …
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
Matched Synonyms: … genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate
Experimental
Matched Name: … 2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … tert-butyl N-[(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Matched Iupac: … tert-butyl N-[(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists ... Sex Hormones and Insulins …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists ... Sex Hormones and Insulins …
Olenasufligene relduparvovec
Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Elranatamab
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ... IMMUNOGLOBULIN G2 (224-ARGININE,265-ALANINE,330-SERINE,331-SERINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Intermedine
Investigational
Matched Synonyms: … -melanotropin (human) ... Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
Glenzocimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BR-007
Investigational
Matched Synonyms: … -4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethoxy)carbonyl)amino)butane-1,1-diyl)bis(hydrogen phosphonate …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and ... It functions by preventing resorption of bone[FDA Label][A959]. …
Matched Mixtures name: … BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... BONYL 70 MG/2800 IU TABLET, 12 ADET ... BONEX-D 70 MG / 2800 IU TABLET, 4 ADET …
Matched Salts name: … Alendronate calcium …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... Bone Density Conservation Agents …
Matched Products: … BONEX 70 MG TABLET, 4 ADET …
Matched Mixtures name: … BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... BONYL 70 MG/2800 IU TABLET, 12 ADET ... BONEX-D 70 MG / 2800 IU TABLET, 4 ADET …
Matched Salts name: … Alendronate calcium …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... Bone Density Conservation Agents …
Matched Products: … BONEX 70 MG TABLET, 4 ADET …
Choline alfoscerate
A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Experimental
Investigational
Matched Synonyms: … (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Displaying drugs 1351 - 1375 of 1467 in total