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Lumasiran is a small interfering RNA used in the treatment of primary hyperoxaluria type 1 (PH1). This condition, caused by a deficiency in the enzyme alanine-glyoxylate aminotransferase, leads to an accumulation of oxalate, causing calcium crystal formation. These patients experience frequent kidney stones, nephrocalcinosis, and renal failure. Oxlumo, producted by...
Approved
Investigational
Matched Description: … ], and renal transplant. ... therapy consisted of symptomatic treatment such as hyperhydration, inhibitors of crystallization, [pyridoxine ... [L23554] These patients experience frequent kidney stones, nephrocalcinosis, and renal failure. …
Matched Salts name: … Lumasiran sodium
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Displaying all 2 drugs