Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population.
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Gu H, Kimm K, Lee JK, Oh B
Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population.
Tissue Antigens. 2005 May;65(5):503-4.
- PubMed ID
- 15853909 [ View in PubMed]
- Abstract
The polymorphism of HLA class II genes is largely confined to the exon 2 region. Sequence analysis of exon 2 of the DQB1 gene revealed the novel polymorphism in the Korean population. The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG-->GGG), corresponding to non-synonymous amino acid change (Glu-->Gly).