Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.
Article Details
- CitationCopy to clipboard
Clemons WM Jr, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V
Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.
Nature. 1999 Aug 26;400(6747):833-40. doi: 10.1038/23631.
- PubMed ID
- 10476960 [ View in PubMed]
- Abstract
The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.
DrugBank Data that Cites this Article
- Polypeptides
Name UniProt ID 30S ribosomal protein S15 Q5SJ76 Details 30S ribosomal protein S20 P80380 Details 30S ribosomal protein S4 P80373 Details 30S ribosomal protein S5 Q5SHQ5 Details 30S ribosomal protein S6 Q5SLP8 Details 30S ribosomal protein S7 P17291 Details 30S ribosomal protein S17 P0DOY7 Details 30S ribosomal protein S8 P0DOY9 Details