Effectiveness evaluation of cardiovascular drugs based on CYP2C9 target protein.

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Guo G, Zhao Y, Chai J, Hao D, Song F

Effectiveness evaluation of cardiovascular drugs based on CYP2C9 target protein.

Pak J Pharm Sci. 2015 Jul;28(4 Suppl):1545-9.

PubMed ID

26431654 [ View in PubMed

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Abstract

This study is to discuss the effectiveness evaluation of cardiovascular drugs based on CYP2C9 target protein. Multilevel fuzzy comprehensive evaluation method was taken to evaluate the individualized medication effectiveness for cardiovascular drug under the function of CYP2P9 target protein. Then, it was established for the index system to affect drug efficacy and index weight was settled. This index system was applied on the study of valsartan drugs to evaluate the drug efficacy rate of sample. Results corresponded with the actual drug treatment, and received better verification. The beneficial exploration was performed for the effectiveness evaluation of individualized administration.

DrugBank Data that Cites this Article

Drug Enzymes

Drug	Enzyme	Kind	Organism	Pharmacological Action	Actions
Valsartan	Cytochrome P450 2C9	Protein	Humans	Unknown	Substrate	Details