Comparison of the pharmacology of nafarelin and danazol.
Article Details
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Barbieri RL
Comparison of the pharmacology of nafarelin and danazol.
Am J Obstet Gynecol. 1990 Feb;162(2):581-5.
- PubMed ID
- 2137975 [ View in PubMed]
- Abstract
The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Nafarelin Gonadotropin-releasing hormone receptor Protein Humans YesAgonistDetails Nafarelin Putative gonadotropin-releasing hormone II receptor Protein Humans YesAgonistDetails