Signaling by dual specificity kinases.
Article Details
- CitationCopy to clipboard
Dhanasekaran N, Premkumar Reddy E
Signaling by dual specificity kinases.
Oncogene. 1998 Sep 17;17(11 Reviews):1447-55.
- PubMed ID
- 9779990 [ View in PubMed]
- Abstract
Dual specificity kinases that phosphorylate the Thr- and Tyr-residues within the TXY motif of MAP-kinases of play a central role in the regulation of various processes of cell growth. These dual specificity kinases also known as MAP kinase kinases are constituents of the sequential kinase signaling modules. Seven distinct mammalian MAP kinases kinases have been identified. Some of the unique signaling properties of these kinases are discussed here.