Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.
Article Details
- CitationCopy to clipboard
Connors RV, Wang Z, Harrison M, Zhang A, Wanska M, Hiscock S, Fox B, Dore M, Labelle M, Sudom A, Johnstone S, Liu J, Walker NP, Chai A, Siegler K, Li Y, Coward P
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.
Bioorg Med Chem Lett. 2009 Jul 1;19(13):3550-4. doi: 10.1016/j.bmcl.2009.04.151. Epub 2009 May 9.
- PubMed ID
- 19464171 [ View in PubMed]
- Abstract
The discovery and optimization of a series of potent PPARdelta full agonists with partial agonistic activity against PPARgamma is described.