Thiamine transporter 1
Details
- Name
- Thiamine transporter 1
- Synonyms
- Solute carrier family 19 member 2
- TC1
- Thiamine carrier 1
- THT1
- ThTr-1
- TRMA
- Gene Name
- SLC19A2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0006803|Thiamine transporter 1 MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP DKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQG LLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILV SVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTD TPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSV WWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWST WGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERY ALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMK KCRKLEDPQSSSQVTTS
- Number of residues
- 497
- Molecular Weight
- 55399.49
- Theoretical pI
- 6.72
- GO Classification
- Functionsfolic acid transporter activity / thiamine transmembrane transporter activity / thiamine uptake transmembrane transporter activityProcessesdrug transmembrane transport / folic acid transport / small molecule metabolic process / thiamine transmembrane transport / thiamine transport / thiamine-containing compound metabolic process / vitamin metabolic process / water-soluble vitamin metabolic processComponentsintegral component of membrane / integral component of plasma membrane / plasma membrane
- General Function
- Thiamine uptake transmembrane transporter activity
- Specific Function
- High-affinity transporter for the intake of thiamine.
- Pfam Domain Function
- Folate_carrier (PF01770)
- Transmembrane Regions
- 29-46 73-91 100-118 129-149 166-185 192-208 286-310 338-354 364-380 387-409 420-443 456-479
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0012459|Thiamine transporter 1 (SLC19A2) ATGGATGTGCCCGGCCCGGTGTCTCGGCGGGCGGCGGCGGCGGCGGCCACTGTGCTCCTG CGGACCGCTCGGGTCCGTCGCGAATGCTGGTTCTTGCCGACCGCGCTGCTCTGCGCCTAC GGCTTCTTCGCCAGCCTCAGGCCGTCCGAGCCCTTCCTGACCCCGTACCTGCTGGGGCCG GACAAGAACCTGACCGAGAGGGAGGTCTTCAATGAAATTTATCCAGTATGGACTTACTCT TACCTGGTGCTACTGTTTCCTGTGTTCCTTGCCACAGACTACCTCCGTTATAAACCTGTT GTTCTACTGCAGGGGCTCAGCCTTATTGTTACATGGTTTATGCTGCTCTATGCCCAGGGA CTGCTGGCCATTCAATTTCTAGAATTTTTTTATGGCATCGCCACAGCCACTGAAATTGCC TATTACTCTTATATCTACAGTGTGGTGGACCTGGGCATGTACCAGAAAGTCACAAGTTAC TGTCGAAGTGCCACTTTGGTGGGCTTTACAGTGGGCTCTGTCCTAGGGCAAATCCTTGTC TCAGTGGCAGGCTGGTCGCTGTTCAGCCTGAATGTCATCTCTCTTACCTGTGTTTCAGTG GCTTTTGCTGTGGCCTGGTTTTTACCTATGCCACAGAAGAGCCTCTTCTTTCACCACATT CCTTCTACCTGCCAGAGAGTGAATGGCATCAAGGTACAAAATGGTGGCATTGTTACTGAC ACCCCAGCTTCTAACCACCTTCCTGGCTGGGAGGACATTGAGTCAAAAATCCCTCTAAAT ATGGAGGAGCCTCCCGTGGAGGAACCGGAACCCAAGCCAGACCGTCTCCTTGTATTGAAA GTACTATGGAATGATTTCCTGATGTGCTACTCCTCTCGCCCTCTTCTCTGCTGGTCTGTG TGGTGGGCCCTCTCTACCTGTGGCTATTTTCAAGTTGTGAACTACACACAGGGCCTGTGG GAGAAAGTGATGCCTTCTCGCTATGCTGCTATCTATAATGGTGGCGTGGAGGCCGTTTCA ACCTTACTGGGTGCTGTTGCTGTGTTTGCAGTTGGTTATATAAAAATATCCTGGTCAACT TGGGGAGAAATGACATTATCTCTCTTTTCTCTCCTGATTGCTGCTGCAGTGTATATCATG GACACTGTGGGTAACATTTGGGTGTGCTATGCATCCTATGTTGTCTTCAGAATCATCTAC ATGTTACTCATCACGATAGCAACTTTTCAAATTGCTGCAAACCTCAGCATGGAACGCTAT GCCCTAGTATTTGGTGTAAATACCTTCATTGCCCTGGCACTGCAGACGCTGCTCACTCTA ATTGTGGTAGATGCCAGTGGCCTTGGATTAGAAATTACCACTCAGTTTTTGATCTATGCC AGTTATTTTGCACTCATCGCTGTGGTTTTCCTGGCCAGTGGTGCAGTCAGTGTTATGAAG AAATGTAGAAAGCTGGAAGATCCACAATCAAGTTCTCAAGTAACCACTTCATAA
- Chromosome Location
- 1
- Locus
- 1q23.3
- External Identifiers
Resource Link UniProtKB ID O60779 UniProtKB Entry Name S19A2_HUMAN GenBank Protein ID 6524689 GenBank Gene ID AF160812 HGNC ID HGNC:10938 - General References
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