Glycoside Hydrolases

DrugDrug NameDrug Indication
DB00070Hyaluronidase (ovine)For increase of absorption and distribution of other injected drugs and for rehydration.
DB00053ImigluceraseFor the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
DB00088AlgluceraseFor the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
DB00103Agalsidase betaFor treatment of Fabry's disease (alpha-galactosidase A deficiency)
DB01272Alglucosidase alfaFor the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.
DB05330ALTU-135Investigated for use/treatment in cystic fibrosis and pancreatic disorders.
DB06760SacrosidaseFor the treatment of congenital sucrose-isomaltase deficiency (CSID).
DB08876Taliglucerase alfaFor the treatment of adult Type 1 Gaucher disease.
DB11065Pancrelipase amylasePlease refer to [DB00085].
DB12684AviscumineNot Available
DB13260LysozymeNot Available
DB13761TilactaseTilactase is indicated for the symptomatic treatment of lactose intolerance in infants and older patients requiring a parenteral nutrition or fluid diet.[L2338] Lactose intolerance occurs when there is an existence of an inability to break down lactose which is commonly found in dairy products. This inability occurs when the lactase levels are reduced and thus there is no via to digest and break down the lactose. The undigested lactose moves into the large intestine where normal flora bacteria can interact with it and cause bloating, gas and diarrhea.[A32592]
DB06205Vorhyaluronidase alfaIndicated as an adjuvant to increase the absorption and dispersion of other injected drugs; for hypodermoclysis; and as an adjunct in subcutaneous urography for improving resorption of radiopaque agents.
DB00090LaronidaseFor the treatment of mucopolysaccharidosis
DB14740HyaluronidaseNot Available
DB15336Valanafusp alfaNot Available