Amino Acids, Neutral

Amino acids with uncharged R groups or side chains.
DrugDrug NameDrug Indication
DB00118AdemetionineS-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as a dietary supplement for the support of bone and joint health, as well as mood and emotional well being.
DB00130L-GlutamineUsed for nutritional supplementation, also for treating dietary shortage or imbalance. Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older [FDA Label].
DB00133SerineUsed as a natural moisturizing agent in some cosmetics and skin care products.
DB00134MethionineUsed for protein synthesis including the formation of SAMe, L-homocysteine, L-cysteine, taurine, and sulfate.
DB00138CystineIt has been claimed that L-cysteine has anti-inflammatory properties, that it can protect against various toxins, and that it might be helpful in osteoarthritis and rheumatoid arthritis. More research will have to be done before L-cysteine can be indicated for any of these conditions. Research to date has mostly been in animal models.
DB00151L-CysteineFor the prevention of liver damage and kidney damage associated with overdoses of acetaminophen
DB00156L-ThreonineL-Threonine makes up collagen, elastin, and enamel protein. It aids proper fat metabolism in the liver, helps the digestive and intestinal tracts function more smoothly, and assists in metabolism and assimilation.
DB00174AsparagineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
DB00260CycloserineUsed in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
DB01646N-AcetylmethionineNot Available
DB02216S-MethylcysteineNot Available
DB02235L-methionine (R)-S-oxideNot Available
DB02345SelenocysteineNot Available
DB02608N-Acetyl-P-NitrophenylserinolNot Available
DB03544S-PhosphocysteineNot Available
DB03799TrifluoromethionineNot Available
DB04167AceglutamideNot Available
DB04370S-sulphocysteineNot Available
DB04464N-FormylmethionineNot Available
DB04527beta-HydroxyasparagineNot Available
DB06151AcetylcysteineAcetylcysteine is used mainly as a mucolytic and in the management of paracetamol (acetaminophen) overdose.
DB06262DroxidopaFor treatment of neurogenic orthostatic hypotension (NOH) associated with various disorders including Multiple System Atrophy, Familial Amyloid Polyneuropathy, hemodialysis induced hypotension and Parkinson's Disease. Also investigated for use/treatment in neurologic disorders, nephropathy, blood (blood forming organ disorders, unspecified), and dizzy/fainting spells.
DB11142SelenomethionineNot Available
DB11956DelanzomibNot Available
DB12160BucillamineNot Available
DB12697MethylselenocysteineNot Available
DB12870Buthionine SulfoximineNot Available
DB12882OmbrabulinNot Available
DB13431ProglumideNot Available
DB13972RacemethionineNot Available
DB14103Methionine sulfoximineNot Available
DB14480Acetylcysteine amideNot Available
DrugDrug NameTargetType
DB00118AdemetionineGlycine N-methyltransferasetarget
DB00118AdemetionineS-adenosylmethionine decarboxylase proenzymetarget
DB00118AdemetionineS-adenosylmethionine synthase isoform type-2target
DB00118AdemetionineCystathionine beta-synthasetarget
DB00118AdemetionineS-adenosylmethionine synthase isoform type-1target
DB00118AdemetionineCytochrome P450 2E1enzyme
DB00118AdemetionineCatechol O-methyltransferasetarget
DB00118AdemetionineSpermidine synthaseenzyme
DB00118AdemetionineCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1target
DB00118AdemetionineArsenite methyltransferasetarget
DB00130L-GlutamineCTP synthase 1target
DB00130L-GlutamineAmidophosphoribosyltransferasetarget
DB00130L-GlutamineGlutamine synthetasetarget
DB00130L-GlutamineMonocarboxylate transporter 10transporter
DB00130L-GlutamineCoagulation factor XIII A chainenzyme
DB00130L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
DB00130L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
DB00130L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
DB00130L-GlutamineNeutral amino acid transporter B(0)transporter
DB00130L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
DB00130L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
DB00130L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
DB00130L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
DB00130L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
DB00130L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
DB00130L-GlutamineCAD proteinenzyme
DB00130L-GlutamineGlutamine--tRNA ligaseenzyme
DB00130L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
DB00130L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
DB00133SerineCystathionine beta-synthasetarget
DB00133SerineL-serine dehydratase/L-threonine deaminasetarget
DB00133SerineSerine racemasetarget
DB00133SerineSerine palmitoyltransferase 2target
DB00133SerineSerine palmitoyltransferase 1target
DB00133SerineSerine--tRNA ligase, cytoplasmictarget
DB00133SerineSerine--pyruvate aminotransferasetarget
DB00133SerineMonocarboxylate transporter 10transporter
DB00134MethionineMethionine synthase reductasetarget
DB00134MethionineMethionine synthasetarget
DB00134MethionineMethionine aminopeptidase 2target
DB00134MethionineBetaine--homocysteine S-methyltransferase 1target
DB00134MethionineS-methylmethionine--homocysteine S-methyltransferase BHMT2target
DB00134MethionineGlutamine synthetaseenzyme
DB00134MethionineMethylenetetrahydrofolate reductaseenzyme
DB00134MethionineMonocarboxylate transporter 10transporter
DB00134MethionineS-adenosylmethionine synthase isoform type-2enzyme
DB00134MethionineMethionine-R-sulfoxide reductase B2, mitochondrialenzyme
DB00134MethionineS-adenosylmethionine synthase isoform type-1enzyme
DB00134MethionineMethionine-R-sulfoxide reductase B1enzyme
DB00134MethionineMitochondrial peptide methionine sulfoxide reductaseenzyme
DB00134MethionineMethionine--tRNA ligase, cytoplasmicenzyme
DB00134MethionineMethionine--tRNA ligase, mitochondrialenzyme
DB00134MethionineMethionine adenosyltransferase 2 subunit betaenzyme
DB00138CystineCystine/glutamate transportertarget
DB00138CystineCystinosintarget
DB00138CystineB(0,+)-type amino acid transporter 1target
DB00138CystineNeutral and basic amino acid transport protein rBATtarget
DB00138CystineMonocarboxylate transporter 10transporter
DB00151L-CysteineCysteine--tRNA ligase, cytoplasmictarget
DB00151L-CysteineGlutamate--cysteine ligase regulatory subunittarget
DB00151L-CysteineGlutamate--cysteine ligase catalytic subunittarget
DB00151L-CysteineAspartate aminotransferase, cytoplasmictarget
DB00151L-CysteineCystathionine gamma-lyasetarget
DB00151L-CysteineCystathionine beta-synthasetarget
DB00151L-CysteineCysteine dioxygenase type 1target
DB00151L-CysteineMethylated-DNA--protein-cysteine methyltransferasetarget
DB00151L-CysteineGlutathione synthetasetarget
DB00151L-CysteineThiamine transporter 2target
DB00151L-CysteineProbable cysteine--tRNA ligase, mitochondrialtarget
DB00151L-CysteineCysteine sulfinic acid decarboxylasetarget
DB00151L-CysteineCysteine desulfurase, mitochondrialtarget
DB00151L-CysteineMonocarboxylate transporter 10transporter
DB00156L-ThreonineThreonine synthase-like 1target
DB00156L-ThreonineThreonine--tRNA ligase, cytoplasmictarget
DB00156L-ThreonineThreonine--tRNA ligase, mitochondrialtarget
DB00156L-ThreonineMonocarboxylate transporter 10transporter
DB00174AsparagineNeutral amino acid transporter B(0)target
DB00174AsparagineAsparagine synthetase [glutamine-hydrolyzing]target
DB00174AsparagineAsparagine--tRNA ligase, cytoplasmictarget
DB00174AsparagineIsoaspartyl peptidase/L-asparaginasetarget
DB00174AsparagineProbable asparagine--tRNA ligase, mitochondrialtarget
DB00174AsparagineSodium-coupled neutral amino acid transporter 3target
DB00174AsparagineMonocarboxylate transporter 10transporter
DB00260CycloserineD-alanine--D-alanine ligase Atarget
DB00260CycloserineAlanine racemasetarget
DB00260CycloserineAromatic-L-amino-acid decarboxylaseenzyme
DB00260CycloserineProton-coupled amino acid transporter 2transporter
DB01646N-AcetylmethionineN-acylamino acid racemasetarget
DB01646N-AcetylmethionineRhodopsintarget
DB02216S-MethylcysteineCathepsin Dtarget
DB02216S-MethylcysteineFatty acid-binding protein, livercarrier
DB02216S-MethylcysteineMethylated-DNA--protein-cysteine methyltransferasetarget
DB02235L-methionine (R)-S-oxideCatalasetarget
DB02235L-methionine (R)-S-oxideProteasetarget
DB02235L-methionine (R)-S-oxideAmyloid beta A4 proteintarget
DB02345SelenocysteineCathelicidin antimicrobial peptidetarget
DB02345SelenocysteineNucleoside diphosphate kinase Atarget
DB02345SelenocysteineFormate dehydrogenase Htarget
DB02345SelenocysteineCysteine desulfurasetarget
DB02608N-Acetyl-P-NitrophenylserinolChloramphenicol 3-O phosphotransferasetarget
DB03544S-PhosphocysteineN,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB componenttarget
DB03544S-PhosphocysteineEnamine/imine deaminasetarget
DB03799TrifluoromethionineMethionine--tRNA ligasetarget
DB03799TrifluoromethionineMethionine aminopeptidasetarget
DB04167AceglutamideN-acylamino acid racemasetarget
DB04464N-FormylmethionineGlutamate--cysteine ligasetarget
DB04464N-FormylmethionineRibonuclease pancreatictarget
DB04464N-FormylmethioninePutative ATP-dependent Clp protease proteolytic subunit, mitochondrialtarget
DB04464N-FormylmethionineGeranylgeranyl transferase type-2 subunit alphatarget
DB04464N-FormylmethionineGeranylgeranyl transferase type-2 subunit betatarget
DB04464N-FormylmethioninePhotosynthetic reaction center cytochrome c subunittarget
DB04464N-FormylmethionineReaction center protein H chaintarget
DB04464N-FormylmethionineReaction center protein L chaintarget
DB04464N-FormylmethionineReaction center protein M chaintarget
DB04464N-FormylmethionineLight-harvesting protein B-800/820 alpha chaintarget
DB04464N-FormylmethionineLight-harvesting protein B-800/820 beta chaintarget
DB04464N-FormylmethionineLight-harvesting protein B-800/850 alpha chaintarget
DB04464N-FormylmethionineLight-harvesting protein B-800/850 beta chaintarget
DB04464N-FormylmethionineAntithrombin-IIItarget
DB04464N-FormylmethionineBeta-2-microglobulintarget
DB04464N-FormylmethionineNADH-ubiquinone oxidoreductase chain 1target
DB04464N-FormylmethionineHLA class I histocompatibility antigen, B-27 alpha chaintarget
DB04464N-FormylmethionineRespiratory nitrate reductase 1 alpha chaintarget
DB04464N-FormylmethionineRespiratory nitrate reductase 1 beta chaintarget
DB04464N-FormylmethionineRespiratory nitrate reductase 1 gamma chaintarget
DB04464N-FormylmethionineProtein S100-Gtarget
DB04464N-FormylmethionineRubredoxintarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 1target
DB04464N-FormylmethionineCytochrome c oxidase subunit 2target
DB04464N-FormylmethionineCytochrome c oxidase subunit 3target
DB04464N-FormylmethionineCytochrome c oxidase subunit 5A, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 5B, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 6Ctarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 7B, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 7C, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 8A, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 6A2, mitochondrialtarget
DB04464N-FormylmethionineCytochrome c oxidase subunit 6B1target
DB04464N-FormylmethionineCytochrome c oxidase subunit 7A1, mitochondrialtarget
DB04464N-FormylmethionineMethionyl-tRNA formyltransferasetarget
DB04464N-FormylmethionineStreptavidintarget
DB04464N-FormylmethionineProtein S100-Btarget
DB04464N-FormylmethionineDelta-hemolysintarget
DB04464N-FormylmethioninePolyubiquitin-Ctarget
DB04464N-FormylmethionineAtpHtarget
DB04464N-FormylmethionineProbable L-ascorbate-6-phosphate lactonase UlaGtarget
DB04464N-FormylmethionineImmunoglobulin G-binding protein Gtarget
DB04527beta-HydroxyasparagineMannan-binding lectin serine protease 2target
DB06151AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
DB06151AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
DB06151AcetylcysteineSolute carrier family 22 member 6transporter
DB06151AcetylcysteineAminoacylase-1target
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB06151AcetylcysteineGlutathione synthetasetarget
DB06151AcetylcysteineCystine/glutamate transportertarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
DB06262DroxidopaPhenylalanine-4-hydroxylasetarget
DB06262DroxidopaAlpha-1A adrenergic receptortarget
DB06262DroxidopaAlpha-1B adrenergic receptortarget
DB06262DroxidopaAlpha-1D adrenergic receptortarget
DB06262DroxidopaAlpha-2A adrenergic receptortarget
DB06262DroxidopaAlpha-2B adrenergic receptortarget
DB06262DroxidopaAlpha-2C adrenergic receptortarget
DB06262DroxidopaBeta-1 adrenergic receptortarget
DB06262DroxidopaBeta-2 adrenergic receptortarget
DB06262DroxidopaBeta-3 adrenergic receptortarget
DB06262DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DB06262DroxidopaMonocarboxylate transporter 10transporter
DB06262DroxidopaSodium-dependent noradrenaline transportertransporter