Organic compounds containing a carbon-nitrogen double bond where a NITROGEN atom can be attached to HYDROGEN or an alkyl or aryl group.
DrugDrug NameDrug Description
DB00172ProlineAn amino acid commonly found as a component of total parenteral nutrition.
DB00419MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
DB00491MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
DB00492FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
DB01197CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
DB02492GhavamiolNot Available
DB02543Pyrrole-2-CarboxylateNot Available
DB02595Bulgecin ANot Available
DB02679CyanamideA cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The...
DB02810N-(2-Acetamido)Iminodiacetic AcidNot Available
DB03088Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
DB03206DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
DB03360N-AcetylprolineNot Available
DB04284L-proline betaineNot Available
DB05018MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
DB08847HydroxyprolineUsed in France as a combination product for the treatment of small, superficial wounds.
DB08873BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
DB09137Technetium Tc-99m mebrofeninA diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests.
DB09164Technetium Tc-99m disofeninA radiopharmaceutical diagnostic agent used for hepatobiliary scans.
DB09230AzelnidipineFor the treatment of hypertension.
DB11364PidotimodFor use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections .
DB11706RaxatrigineRaxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
DB11821DanegaptideDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
DB12224Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
DB13166ZofenoprilZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
DB13363OxaceprolNot Annotated
DB14207FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
DB08766ZofenoprilatNot Available
DB06111AB192Investigated for use/treatment in diabetes mellitus type 2.
DB04545AfegostatNot Available
DB12353UlodesineUlodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
DB14872LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
DB15157VoruciclibVoruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
DrugDrug NameTargetType
DB00172ProlinePyrroline-5-carboxylate reductase 1, mitochondrialtarget
DB00172ProlineBifunctional glutamate/proline--tRNA ligasetarget
DB00172ProlineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)target
DB00172ProlineSodium-dependent proline transportertarget
DB00172ProlinePyrroline-5-carboxylate reductase 2target
DB00172ProlineProlyl 4-hydroxylase subunit alpha-2target
DB00172ProlineProline dehydrogenase 1, mitochondrialtarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Htarget
DB00172ProlineProline synthase co-transcribed bacterial homolog proteintarget
DB00172ProlineProlyl 4-hydroxylase subunit alpha-1target
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Btarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Ctarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Atarget
DB00172ProlinePeptidyl-prolyl cis-trans isomerase Gtarget
DB00172ProlineProlyl 3-hydroxylase 1target
DB00172ProlinePyrroline-5-carboxylate reductasetarget
DB00172ProlineProbable proline--tRNA ligase, mitochondrialtarget
DB00172ProlineProlyl 3-hydroxylase 2target
DB00172ProlineProlyl 3-hydroxylase 3target
DB00172ProlinePyrroline-5-carboxylate reductase 3target
DB00172ProlineTrans-L-3-hydroxyproline dehydratasetarget
DB00172ProlineProline dehydrogenase 1, mitochondrialenzyme
DB00172ProlineMonocarboxylate transporter 10transporter
DB00419MiglustatCeramide glucosyltransferasetarget
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilP-glycoprotein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB02492GhavamiolAlpha-mannosidase 2target
DB02543Pyrrole-2-CarboxylateMonomeric sarcosine oxidasetarget
DB02595Bulgecin AMembrane-bound lytic murein transglycosylase Btarget
DB02595Bulgecin ASoluble lytic murein transglycosylasetarget
DB02679CyanamideCarbonic anhydrase 2target
DB02679CyanamideCathepsin Ktarget
DB02810N-(2-Acetamido)Iminodiacetic AcidPeptide deformylasetarget
DB03088Pidolic acidAlpha-amylase 2Btarget
DB03088Pidolic acidAngiogenintarget
DB03088Pidolic acidChondroitinase-Btarget
DB03088Pidolic acidAlpha-amylase 1target
DB03088Pidolic acidVascular endothelial growth factor Atarget
DB03088Pidolic acidPancreatic alpha-amylasetarget
DB03088Pidolic acidIg lambda-1 chain C regionstarget
DB03088Pidolic acidIg lambda chain V-II region MGCtarget
DB03088Pidolic acidTrefoil factor 2target
DB03088Pidolic acidCytochrome c2target
DB03088Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
DB03088Pidolic acidEndo-1,4-beta-xylanasetarget
DB03088Pidolic acidDissimilatory copper-containing nitrite reductasetarget
DB03088Pidolic acidKeratin-associated protein 5-2target
DB03088Pidolic acidOrexintarget
DB03088Pidolic acidC-C motif chemokine 8target
DB03088Pidolic acidCytochrome c'target
DB03088Pidolic acidPancreatic alpha-amylaseenzyme
DB03206DuvoglustatCyclomaltodextrin glucanotransferasetarget
DB03206DuvoglustatBeta-glucosidase Atarget
DB03206DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB03206DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB03206DuvoglustatXylose isomerasetarget
DB03360N-Acetylproline(5R)-carbapenem-3-carboxylate synthasetarget
DB04284L-proline betaineGlycine betaine-binding periplasmic proteintarget
DB05018MigalastatAlpha-galactosidase Atarget
DB05018MigalastatUDP-glucuronosyltransferase 1-1enzyme
DB08847HydroxyprolineProton-coupled amino acid transporter 1transporter
DB08873BoceprevirCytochrome P450 3A4enzyme
DB08873BoceprevirCytochrome P450 3A5enzyme
DB08873BoceprevirP-glycoprotein 1transporter
DB08873BoceprevirNS3/4A proteintarget
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B1transporter
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B3transporter
DB09230AzelnidipineCytochrome P450 3A4enzyme
DB09230AzelnidipineVoltage-dependent L-type calcium channel subunit beta-1target
DB13166ZofenoprilAngiotensin-converting enzymetarget
DB08766ZofenoprilatCytosol aminopeptidasetarget
DB06111AB192Myeloperoxidaseenzyme
DB04545AfegostatEndoglucanase 5Atarget
DB04545AfegostatBeta-glucosidase Atarget
DB04545AfegostatPossible cellulase CelA1 (Endoglucanase) (Endo-1,4-beta-glucanase) (FI-cmcase) (Carboxymethyl cellulase)target