Pyridine derivatives with one or more keto groups on the ring.
|Drug||Drug Name||Drug Indication|
|DB00656||Trazodone||Trazodone is indicated for the treatment of major depressive disorder (MDD).[L3484] It has been used off-label for adjunct therapy in alcohol dependence, and off-label to treat anxiety and insomnia.[L3484] It may also be used off-label to treat symptoms of dementia, Alzheimer’s disease, schizophrenia, eating disorders, and fibromyalgia due to its effects on various neurotransmitter receptors.[A31634]|
|DB09194||Etoperidone||Etoperidone has been studied for the treatment of depression[T47], tremors in Parkinson, extrapyramidal symptoms[L1041] and male impotence[L1042]. It is not certain if it was ever approved and marketed but its current status is withdrawn.|
|DB04951||Pirfenidone||For the treatment of idiopathic pulmonary fibrosis (IPF).|
|DB01188||Ciclopirox||Used as a topical treatment in immunocompetent patients with mild to moderate onychomycosis of fingernails and toenails without lunula involvement, due to Trichophyton rubrum.|
|DB08826||Deferiprone||Deferiprone is indicated in thalassemia syndromes when first line chelation agents are not adequate to treat transfusional iron overload.|