Polymyxins
- Name
- Polymyxins
- Accession Number
- DBCAT001129
- Description
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
- ATC Classification
- Drugs
Drug Drug Description Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. - Drugs & Drug Targets
Drug Target Type Colistin Bacterial outer membrane target Colistimethate Bacterial outer membrane target Polymyxin B Bacterial outer membrane target Polymyxin B Solute carrier family 15 member 2 transporter