Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. Melanocortins include ACTH; ALPHA-MSH; and other peptides such as BETA-MSH and GAMMA-MSH, derived from other fragments of POMC. These peptides act through a variety of MELANOCORTIN RECEPTORS to control different functions including steroidogenesis, energy homeostasis, feeding, and skin pigmentation.
|Drug||Drug Name||Drug Indication|
|DB01284||Tetracosactide||For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.|
|DB01285||Corticotropin||For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.|
|DB04931||Afamelanotide||Investigated for use/treatment in actinic keratosis, keratoses, skin cell studies, and skin infections/disorders.|
|DB11653||Bremelanotide||Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of a medication or drug.[L4894]|