Protein Kinase C, antagonists & inhibitors

DrugDrug NameDrug Indication
DB019337-HydroxystaurosporineNot Available
DB02152K-252aNot Available
DB04098BalanolNot Available
DB04367DebromohymenialdisineNot Available
DB06451AprinocarsenInvestigated for use/treatment in lung cancer.
DB06595MidostaurinInvestigated for use/treatment in adult patients with high-risk acute myeloid leukemia (AML) who are FLT3 mutation-positive, agressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB11829RuboxistaurinNot Available
DB11924SafingolNot Available
DB13014HypericinNot Available
DrugDrug NameTargetType
DB019337-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
DB02152K-252aHepatocyte growth factor receptortarget
DB02152K-252aDual specificity mitogen-activated protein kinase kinase 1target
DB04098BalanolcAMP-dependent protein kinase catalytic subunit alphatarget
DB04367DebromohymenialdisineActivated CDC42 kinase 1target
DB04367DebromohymenialdisineDual specificity protein kinase CLK1target
DB06451AprinocarsenProtein kinase C alpha typetarget
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCYP3Aenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB13014HypericinSerum albumincarrier
DB13014HypericinGlutathione S-transferase A1target
DB13014HypericinGlutathione S-transferase Ptarget