Vasodilators Used in Cardiac Diseases

DrugDrug NameDrug Indication
DB00727NitroglycerinFor the prevention of angina
DB00883Isosorbide dinitrateFor the prevention of angina pectoris due to coronary artery disease.
DB01020Isosorbide MononitrateFor the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
DB01613Erythrityl tetranitrateFor the prevention of angina.
DB04825PrenylamineNot Available
DB04899NesiritideFor the intravenous treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
DB05794SerelaxinInvestigated for use/treatment in cardiovascular disorders, congestive heart failure, infertility, peripheral vascular disease, and scleroderma.
DB06154Pentaerythritol tetranitrateUsed for the treatment of angina pectoris [L2393].
DB09220NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
DB09282MolsidomineThe indications for use of molsidomine include ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension [L1370, L1371].
DB09283TrapidilUsed in the treatment of chronic stable angina [A19770].
DB09284ImolamineImolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic.[T83]
DB13228FlosequinanNot Available
DB13255Propatyl nitrateNot Available
DB13265HexobendineNot Available
DB13277BenziodaroneNot Available
DB13279CarbocromenNot Available
DB13291CloridarolNot Available
DB13333EfloxateNot Available
DB13342CinepazetNot Available
DB13398OxyfedrineNot Available
DB13400LinsidomineNot Available
DB13408Methylpropylpropanediol dinitrateNot Available
DB13574HeptaminolNot Available
DB13585Aminoethyl nitrateNot Available
DB13637TenitramineNot Available
DB13715DilazepNot Available
DB13719TrolnitrateNot Available
DB13845EtafenoneNot Available
DrugDrug NameTargetType
DB00727NitroglycerinAtrial natriuretic peptide receptor 1target
DB00727NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
DB00883Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide dinitrateCytochrome P450 3A4enzyme
DB00883Isosorbide dinitrateCytochrome P450 2E1enzyme
DB01020Isosorbide MononitrateCytochrome P450 3A4enzyme
DB01020Isosorbide MononitrateGuanylate cyclase soluble subunit alpha-2target
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
DB04825PrenylamineCalmodulintarget
DB04825PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
DB04825PrenylamineCytochrome P450 3A4enzyme
DB04899NesiritideAtrial natriuretic peptide receptor 1target
DB04899NesiritideAtrial natriuretic peptide receptor 2target
DB04899NesiritideAtrial natriuretic peptide receptor 3target
DB06154Pentaerythritol tetranitrateHemoglobin subunit alphatarget
DB06154Pentaerythritol tetranitrateHemoglobin subunit betatarget
DB06154Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
DB06154Pentaerythritol tetranitrateFree radicalstarget
DB06154Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
DB06154Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
DB09220NicorandilATP-binding cassette sub-family C member 9target
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2target
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
DB09282MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
DB09283TrapidilPlatelet derived growth factor receptor betatarget
DB09283TrapidilCyclic nucleotide phosphodiesterasetarget