OATP1B1/SLCO1B1 Inducers

DrugDrug NameDrug Indication
DB04348Taurocholic AcidNot Available
DB02659Cholic AcidOral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea or complications from decreased fat soluble vitamin absorption.
DB11901ApalutamideIndicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer (NM-CRPC) [FDA Label].
DrugDrug NameTargetType
DB04348Taurocholic AcidBile salt-activated lipasetarget
DB04348Taurocholic AcidGastrotropintarget
DB04348Taurocholic AcidBile salt export pumptransporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB04348Taurocholic AcidIleal sodium/bile acid cotransportertransporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B1transporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 2transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 4transporter
DB04348Taurocholic AcidMultidrug resistance protein 1transporter
DB04348Taurocholic AcidSolute carrier family 22 member 6transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 7transporter
DB04348Taurocholic AcidSolute carrier family 22 member 8transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 4A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family C member 11transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1C1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 3A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family G member 2transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 2B1transporter
DB04348Taurocholic AcidMonocarboxylate transporter 1transporter
DB04348Taurocholic AcidSodium/bile acid cotransportertransporter
DB04348Taurocholic AcidOrganic solute transporter subunit alphatransporter
DB04348Taurocholic AcidOrganic solute transporter subunit betatransporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B3transporter
DB04348Taurocholic AcidCystine/glutamate transportertransporter
DB04348Taurocholic AcidBile acid receptortarget
DB02659Cholic AcidFerrochelatase, mitochondrialtarget
DB02659Cholic AcidBile salt export pumptransporter
DB02659Cholic AcidMultidrug resistance protein 1transporter
DB02659Cholic AcidMultidrug resistance-associated protein 1transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB02659Cholic AcidIleal sodium/bile acid cotransportertransporter
DB02659Cholic AcidCanalicular multispecific organic anion transporter 1transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1B1transporter
DB02659Cholic AcidCanalicular multispecific organic anion transporter 2transporter
DB02659Cholic AcidMultidrug resistance-associated protein 4transporter
DB02659Cholic AcidSodium/bile acid cotransportertransporter
DB02659Cholic AcidSolute carrier family 22 member 8transporter
DB02659Cholic AcidSolute carrier family 22 member 7transporter
DB02659Cholic AcidSolute carrier organic anion transporter family member 1B3transporter
DB02659Cholic AcidAlcohol dehydrogenase 1Ctarget
DB02659Cholic AcidEstrogen-related receptor gammatarget
DB02659Cholic AcidGastrotropintarget
DB02659Cholic AcidCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 1target
DB02659Cholic AcidCytochrome c oxidase subunit 2target
DB02659Cholic AcidCytochrome c oxidase subunit 3target
DB02659Cholic AcidCytochrome c oxidase subunit 5A, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 5B, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6Ctarget
DB02659Cholic AcidCytochrome c oxidase subunit 7B, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 7C, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 8A, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6A2, mitochondrialtarget
DB02659Cholic AcidCytochrome c oxidase subunit 6B1target
DB02659Cholic AcidCytochrome c oxidase subunit 7A1, mitochondrialtarget
DB02659Cholic AcidPhospholipase A2target
DB02659Cholic AcidLiver carboxylesterase 1target
DB02659Cholic AcidFatty acid-binding protein, livercarrier
DB02659Cholic AcidFerrochelatasetarget
DB02659Cholic AcidCholoylglycine hydrolasetarget
DB02659Cholic AcidBile acid receptortarget
DB02659Cholic AcidG-protein coupled bile acid receptor 1target
DB11901ApalutamideAndrogen receptortarget
DB11901ApalutamideCytochrome P450 3A4enzyme
DB11901ApalutamideCytochrome P450 2C8enzyme
DB11901ApalutamideCytochrome P450 2C19enzyme
DB11901ApalutamideCytochrome P450 2C9enzyme
DB11901ApalutamideMultidrug resistance protein 1transporter
DB11901ApalutamideATP-binding cassette sub-family G member 2transporter
DB11901ApalutamideSolute carrier organic anion transporter family member 1B1transporter
DB11901ApalutamideSolute carrier family 22 member 2transporter
DB11901ApalutamideSolute carrier family 22 member 8transporter
DB11901ApalutamideMultidrug and toxin extrusion protein 2transporter
DB11901ApalutamideGABA-A receptor (anion channel)target