Coordination Complexes

Name
Coordination Complexes
Accession Number
DBCAT004979
Description

Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.

Drugs
DrugDrug Description
OxaliplatinA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
GadodiamideA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
Gadopentetic acidA gadolinium compound used as a contrast agent in MRIs.
CarboplatinA alkylating agent used to treat advanced ovarian cancer.
StannsoporfinInvestigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
Motexafin lutetiumInvestigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease.
Motexafin gadoliniumInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).
AEOL-10150Investigated for use/treatment in amyotrophic lateral sclerosis (ALS).
Gadoxetic acidA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize the liver.
GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
Tin protoporphyrin IXNot Available
Zinc mesoporphyrinNot Annotated
Drugs & Drug Targets
DrugTargetType
OxaliplatinDNAtarget
OxaliplatinSolute carrier family 22 member 2transporter
OxaliplatinHigh affinity copper uptake protein 1transporter
OxaliplatinSolute carrier family 22 member 3transporter
OxaliplatinATP-binding cassette sub-family G member 2transporter
OxaliplatinGlutathione S-transferase theta-1enzyme
OxaliplatinMetallothionein-1Aenzyme
OxaliplatinMetallothionein-2enzyme
OxaliplatinMyeloperoxidaseenzyme
OxaliplatinSuperoxide dismutase [Cu-Zn]enzyme
OxaliplatinGlutathione S-transferase Penzyme
OxaliplatinGlutathione S-transferase Mu 1enzyme
OxaliplatinNAD(P)H dehydrogenase [quinone] 1enzyme
OxaliplatinCanalicular multispecific organic anion transporter 1transporter
OxaliplatinCopper-transporting ATPase 2transporter
OxaliplatinCopper-transporting ATPase 1transporter
OxaliplatinSerum albumincarrier
Gadopentetic acid6-phosphogluconate dehydrogenase, decarboxylatingtarget
CarboplatinDNAtarget
CarboplatinHigh affinity copper uptake protein 1transporter
CarboplatinProbable low affinity copper uptake protein 2transporter
CarboplatinXanthine dehydrogenase/oxidaseenzyme
CarboplatinMyeloperoxidaseenzyme
CarboplatinGlutathione S-transferase theta-1enzyme
CarboplatinMetallothionein-1Aenzyme
CarboplatinMetallothionein-2enzyme
CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
CarboplatinGlutathione S-transferase Penzyme
CarboplatinGlutathione S-transferase Mu 1enzyme
CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CarboplatinCopper-transporting ATPase 1transporter
CarboplatinCopper-transporting ATPase 2transporter
CarboplatinATP-binding cassette sub-family G member 2transporter
CarboplatinCanalicular multispecific organic anion transporter 1transporter
StannsoporfinHeme oxygenase 1target
StannsoporfinHeme oxygenase 2target
Motexafin gadoliniumThioredoxin reductase 1, cytoplasmictarget
Motexafin gadoliniumThioredoxin reductase 2, mitochondrialtarget
Motexafin gadoliniumRibonucleoside-diphosphate reductase subunit M2target
Gadoxetic acidSolute carrier organic anion transporter family member 1B1transporter
Gadoxetic acidSolute carrier organic anion transporter family member 1B3transporter
Gadoxetic acidCanalicular multispecific organic anion transporter 2transporter
Gadoxetic acidMultidrug resistance-associated protein 4transporter
Gadoxetic acidCanalicular multispecific organic anion transporter 1transporter