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Identification
NameCarboplatin
Accession NumberDB00958  (APRD00466)
TypeSmall Molecule
GroupsApproved
DescriptionAn organoplatinum compound that possesses antineoplastic activity. [PubChem]
Structure
Thumb
Synonyms
Carboplatin
CBDCA
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Paraplatin
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Carboplatin InjectionLiquid10 mgIntravenousTeva1994-12-31Not applicableCanada
Carboplatin InjectionSolution10 mgIntravenousAccord Healthcare Limited2015-03-11Not applicableCanada
Carboplatin InjectionSolution10 mgIntravenousOmega Laboratories Ltd2013-06-10Not applicableCanada
Carboplatin Injection BPSolution10 mgIntravenousHospira, Inc.1997-07-30Not applicableCanada
Carboplatin Injection Liq 10mg/mlLiquid10 mgIntravenousDavid Bull Laboratories (Pty) Ltd.1992-12-311998-08-13Canada
Carboplatin Injection, BPSolution10 mgIntravenousMylan PharmaceuticalsNot applicableNot applicableCanada
Paraplatin Inj 150mg/vialPowder, for solution150 mgIntravenousBristol Labs Division Of Bristol Myers Squibb1986-12-311996-09-09Canada
Paraplatin-AQ Inj 10mg/mlLiquid10 mgIntravenousBristol Myers Squibb1989-12-312007-07-30Canada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
CarboplatinInjection, solution10 mg/mLIntravenousGland Pharma Limited2017-02-20Not applicableUs
CarboplatinInjection10 mg/mLIntravenousMylan Institutional2011-11-09Not applicableUs
CarboplatinInjection10 mg/mLIntravenousTeva Parenteral Medicines, Inc.2005-11-172016-03-31Us
CarboplatinInjection, solution10 mg/mLIntravenousSagent Pharmaceuticals2013-10-31Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousTeva Parenteral Medicines, Inc.2014-07-31Not applicableUs
CarboplatinSolution450 mg/5mLIntravenousSanja Pharmaceuticals Company2016-09-29Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousHospira Worldwide, Inc.2004-10-142016-10-13Us
CarboplatinInjection10 mg/mLIntravenousMylan Institutional2011-11-09Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousGland Pharma Limited2017-02-20Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousHospira, Inc.2004-10-14Not applicableUs
CarboplatinInjection10 mg/mLIntravenousSun Pharma Global FZE2008-09-192017-02-07Us
CarboplatinInjection, solution10 mg/mLIntravenousTeva Parenteral Medicines, Inc.2006-05-04Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousFresenius Kabi2009-09-15Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousSandoz2010-01-31Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousGland Pharma Limited2017-02-20Not applicableUs
CarboplatinInjection10 mg/mLIntravenousMylan Institutional2011-11-09Not applicableUs
CarboplatinSolution50 mg/5mLIntravenousSanja Pharmaceuticals Company2016-09-29Not applicableUs
CarboplatinInjection10 mg/mLIntravenousSun Pharma Global FZE2008-09-192017-02-07Us
CarboplatinInjection, solution10 mg/mLIntravenousTeva Parenteral Medicines, Inc.2006-05-01Not applicableUs
CarboplatinInjection10 mg/mLIntravenousSun Pharma Global FZE2014-03-03Not applicableUs
CarboplatinInjection10 mg/mLIntravenousMylan Institutional2011-11-09Not applicableUs
CarboplatinInjection, solution10 mg/mLIntravenousGland Pharma Limited2017-02-20Not applicableUs
CarboplatinInjection10 mg/mLIntravenousMylan Institutional2011-11-09Not applicableUs
CarboplatinSolution150 mg/5mLIntravenousSanja Pharmaceuticals Company2016-09-29Not applicableUs
CarboplatinInjection10 mg/mLIntravenousSun Pharma Global FZE2008-09-192017-02-07Us
CarboplatinInjection, solution10 mg/mLIntravenousTeva Parenteral Medicines, Inc.2006-02-01Not applicableUs
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International Brands
NameCompany
ParaplatinNot Available
Paraplatin-AQNot Available
Brand mixturesNot Available
SaltsNot Available
Categories
UNIIBG3F62OND5
CAS number41575-94-4
WeightAverage: 371.254
Monoisotopic: 371.044481331
Chemical FormulaC6H12N2O4Pt
InChI KeyOLESAACUTLOWQZ-UHFFFAOYSA-L
InChI
InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2
IUPAC Name
6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione diamine
SMILES
N.N.O=C1O[Pt]OC(=O)C11CCC1
Pharmacology
IndicationFor the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of PARAPLATIN and cyclophosphamide. It is also indicated for the palliative treatment of patients with ovarian carcinoma recurrent after prior chemotherapy, including patients who have been previously treated with cisplatin.
Structured Indications
PharmacodynamicsCarboplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Mechanism of actionAlkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their attempts to replace the alkylated bases, preventing DNA synthesis and RNA transcription from the affected DNA, 2) DNA damage via the formation of cross-links (bonds between atoms in the DNA) which prevents DNA from being separated for synthesis or transcription, and 3) the induction of mispairing of the nucleotides leading to mutations.
TargetKindPharmacological actionActionsOrganismUniProt ID
DNANucleotideyes
cross-linking/alkylation
Humannot applicabledetails
Related Articles
AbsorptionThe Cmax values and areas under the plasma concentration versus time curves from 0 to infinity (AUC inf) increase linearly with dose, although the increase was slightly more than dose proportional. Carboplatin exhibits linear pharmacokinetics.
Volume of distribution
  • 16 L [apparent volume of distribution, 30 minute IV infusion of 300 mg/m^2 to 500 mg/m^2]
Protein bindingCarboplatin is not bound to plasma protein. However, the platinum itself from carboplatin irreversibly binds to plasma proteins and is slowly eliminated with a minimum half-life of 5 days.
MetabolismNot Available
Route of eliminationThe major route of elimination of carboplatin is renal excretion. After 24 hours, all of the platinum is recovered in the urine as carboplatin. Whether biliary excretion occurs is not known.
Half lifeInitial plasma half-life (alpha) = 1.1 to 2 hours; Post distribution plasma half-life (beta) = 2.6 - 5.9 hours.
Clearance
  • 4.4 L/hour [total body clearance, 30 minute IV infusion of 300 mg/m^2 to 500 mg/m^2]
ToxicityToxic by ingestion. May be create toxic effect through inhalation or skin contact. May cause reproductive defects. May act as a sensitizer. ORL-RAT LD50 343 mg kg-1; SCN-RAT LD50 72 mg kg-1; IPN-MUS LD50 118 mg kg-1
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
AcetyldigitoxinAcetyldigitoxin may decrease the cardiotoxic activities of Carboplatin.Approved
AclarubicinAclarubicin may increase the ototoxic activities of Carboplatin.Investigational
ALT-110The risk or severity of adverse effects can be increased when Carboplatin is combined with ALT-110.Investigational
AmikacinAmikacin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
AmrubicinAmrubicin may increase the ototoxic activities of Carboplatin.Approved, Investigational
annamycinannamycin may increase the ototoxic activities of Carboplatin.Investigational
ApramycinApramycin may increase the ototoxic activities of Carboplatin.Experimental, Vet Approved
ArbekacinArbekacin may increase the ototoxic activities of Carboplatin.Approved
BCGThe therapeutic efficacy of Bcg can be decreased when used in combination with Carboplatin.Investigational
BevacizumabBevacizumab may increase the cardiotoxic activities of Carboplatin.Approved, Investigational
BexaroteneThe serum concentration of Bexarotene can be increased when it is combined with Carboplatin.Approved, Investigational
CabazitaxelCarboplatin may increase the myelosuppressive activities of Cabazitaxel.Approved
CDX-110The risk or severity of adverse effects can be increased when Carboplatin is combined with CDX-110.Investigational
ClozapineThe risk or severity of adverse effects can be increased when Carboplatin is combined with Clozapine.Approved
CyclophosphamideCyclophosphamide may increase the cardiotoxic activities of Carboplatin.Approved, Investigational
DaunorubicinDaunorubicin may increase the ototoxic activities of Carboplatin.Approved
DenosumabThe risk or severity of adverse effects can be increased when Denosumab is combined with Carboplatin.Approved
DeslanosideDeslanoside may decrease the cardiotoxic activities of Carboplatin.Approved
DigitoxinDigitoxin may decrease the cardiotoxic activities of Carboplatin.Approved
DigoxinDigoxin may decrease the cardiotoxic activities of Carboplatin.Approved
DihydrostreptomycinDihydrostreptomycin may increase the ototoxic activities of Carboplatin.Vet Approved
DocetaxelCarboplatin may increase the myelosuppressive activities of Docetaxel.Approved, Investigational
DoxorubicinDoxorubicin may increase the ototoxic activities of Carboplatin.Approved, Investigational
EltrombopagThe serum concentration of Carboplatin can be increased when it is combined with Eltrombopag.Approved
EpirubicinEpirubicin may increase the ototoxic activities of Carboplatin.Approved
FingolimodCarboplatin may increase the immunosuppressive activities of Fingolimod.Approved, Investigational
FosphenytoinThe serum concentration of Fosphenytoin can be decreased when it is combined with Carboplatin.Approved
FramycetinFramycetin may increase the ototoxic activities of Carboplatin.Approved
G17DTThe risk or severity of adverse effects can be increased when Carboplatin is combined with G17DT.Investigational
GeneticinGeneticin may increase the ototoxic activities of Carboplatin.Experimental
GentamicinGentamicin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
GENTAMICIN C1AGENTAMICIN C1A may increase the ototoxic activities of Carboplatin.Experimental
GI-5005The risk or severity of adverse effects can be increased when Carboplatin is combined with GI-5005.Investigational
Hygromycin BHygromycin B may increase the ototoxic activities of Carboplatin.Vet Approved
IdarubicinIdarubicin may increase the ototoxic activities of Carboplatin.Approved
INGN 201The risk or severity of adverse effects can be increased when Carboplatin is combined with INGN 201.Investigational
INGN 225The risk or severity of adverse effects can be increased when Carboplatin is combined with INGN 225.Investigational
INNO-206INNO-206 may increase the ototoxic activities of Carboplatin.Investigational
KanamycinKanamycin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
LeflunomideThe risk or severity of adverse effects can be increased when Carboplatin is combined with Leflunomide.Approved, Investigational
MetamizoleThe risk or severity of adverse effects can be increased when Metamizole is combined with Carboplatin.Withdrawn
MetrizamideMetrizamide may increase the ototoxic activities of Carboplatin.Approved
NatalizumabThe risk or severity of adverse effects can be increased when Carboplatin is combined with Natalizumab.Approved, Investigational
NeamineNeamine may increase the ototoxic activities of Carboplatin.Experimental
NeomycinNeomycin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
NetilmicinNetilmicin may increase the ototoxic activities of Carboplatin.Approved
OleandrinAnvirzel may decrease the cardiotoxic activities of Carboplatin.Experimental
OuabainOuabain may decrease the cardiotoxic activities of Carboplatin.Approved
PaclitaxelCarboplatin may increase the myelosuppressive activities of Paclitaxel.Approved, Vet Approved
ParomomycinParomomycin may increase the ototoxic activities of Carboplatin.Approved, Investigational
PhenytoinThe serum concentration of Phenytoin can be decreased when it is combined with Carboplatin.Approved, Vet Approved
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Carboplatin.Approved, Investigational
PirarubicinPirarubicin may increase the ototoxic activities of Carboplatin.Investigational
PlicamycinPlicamycin may increase the ototoxic activities of Carboplatin.Approved, Withdrawn
PuromycinPuromycin may increase the ototoxic activities of Carboplatin.Experimental
Rabies vaccineThe risk or severity of adverse effects can be increased when Carboplatin is combined with Rabies vaccine.Approved
Rabies vaccineThe therapeutic efficacy of Rabies vaccine can be decreased when used in combination with Carboplatin.Approved
RibostamycinRibostamycin may increase the ototoxic activities of Carboplatin.Approved
RoflumilastRoflumilast may increase the immunosuppressive activities of Carboplatin.Approved
RolapitantThe serum concentration of Carboplatin can be increased when it is combined with Rolapitant.Approved
Sipuleucel-TThe therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Carboplatin.Approved
SisomicinSisomicin may increase the ototoxic activities of Carboplatin.Investigational
SorafenibThe risk or severity of adverse effects can be increased when Sorafenib is combined with Carboplatin.Approved, Investigational
SP1049CSP1049C may increase the ototoxic activities of Carboplatin.Investigational
SpectinomycinSpectinomycin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
SRP 299The risk or severity of adverse effects can be increased when Carboplatin is combined with SRP 299.Investigational
StreptomycinStreptomycin may increase the ototoxic activities of Carboplatin.Approved, Vet Approved
StreptozocinStreptozocin may increase the ototoxic activities of Carboplatin.Approved
TacrolimusThe risk or severity of adverse effects can be increased when Tacrolimus is combined with Carboplatin.Approved, Investigational
TeriflunomideThe serum concentration of Carboplatin can be increased when it is combined with Teriflunomide.Approved
TG4010The risk or severity of adverse effects can be increased when Carboplatin is combined with TG4010.Investigational
TobramycinTobramycin may increase the ototoxic activities of Carboplatin.Approved, Investigational
TofacitinibCarboplatin may increase the immunosuppressive activities of Tofacitinib.Approved, Investigational
TopotecanThe risk or severity of adverse effects can be increased when Carboplatin is combined with Topotecan.Approved, Investigational
TrastuzumabTrastuzumab may increase the cardiotoxic activities of Carboplatin.Approved, Investigational
ValrubicinValrubicin may increase the ototoxic activities of Carboplatin.Approved
ZorubicinZorubicin may increase the ototoxic activities of Carboplatin.Experimental
Food Interactions
  • Avoid echinacea as it may decrease effectiveness of immunosuppresants like carboplatin
References
Synthesis Reference

Jingzun Wang, Huisheng Qu, Lei Wang, Ting Wang, “Supermolecular carboplatin derivatives, their preparation and pharmaceutical composition containing them as active ingredient and applications of the compositions.” U.S. Patent US07259270, issued August 21, 2007.

US07259270
General References
  1. Natarajan G, Malathi R, Holler E: Increased DNA-binding activity of cis-1,1-cyclobutanedicarboxylatodiammineplatinum(II) (carboplatin) in the presence of nucleophiles and human breast cancer MCF-7 cell cytoplasmic extracts: activation theory revisited. Biochem Pharmacol. 1999 Nov 15;58(10):1625-9. [PubMed:10535754 ]
  2. Knox RJ, Friedlos F, Lydall DA, Roberts JJ: Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA. Cancer Res. 1986 Apr;46(4 Pt 2):1972-9. [PubMed:3512077 ]
  3. Canetta R, Rozencweig M, Carter SK: Carboplatin: the clinical spectrum to date. Cancer Treat Rev. 1985 Sep;12 Suppl A:125-36. [PubMed:3002623 ]
External Links
ATC CodesL01XA02
AHFS Codes
  • 10:00.00
PDB EntriesNot Available
FDA labelDownload (1.26 MB)
MSDSDownload (73.5 KB)
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedTreatmentCancer, Breast1
0RecruitingTreatmentBrain Metastasis / Gliomas / Neoplasms, Brain1
0RecruitingTreatmentEndometrial Cancers / Endometrial Carcinoma / Neoplasms, Endometrial1
0RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
0TerminatedTreatmentLymphoma, B-Cell1
1Active Not RecruitingSupportive CareChronic Myeloproliferative Disorders / Drug/Agent Toxicity by Tissue/Organ / Leukemias / Lymphoma NOS / Multiple Myeloma and Plasma Cell Neoplasm / Myelodysplastic Syndromes / Precancerous Conditions / Unspecified Adult Solid Tumor, Protocol Specific1
1Active Not RecruitingTreatmentAdult Acute Megakaryoblastic Leukemia / Adult Acute Monoblastic Leukemia / Adult Acute Monocytic Leukemia / Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 / Adult Acute Myeloid Leukemia With Maturation / Adult Acute Myeloid Leukemia With Minimal Differentiation / Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11 / Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1 / Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 / Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A / Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL / Adult Acute Myeloid Leukemia Without Maturation / Adult Acute Myelomonocytic Leukemia / Adult Erythroleukemia / Adult Pure Erythroid Leukemia / Chronic Myelomonocytic Leukemia / De Novo Myelodysplastic Syndrome / Essential Thrombocythemia (ET) / Hematopoietic and Lymphoid Cell Neoplasm / Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia / Polycythemia Vera (PV) / Previously Treated Myelodysplastic Syndromes / Recurrent Adult Acute Lymphoblastic Leukemia / Recurrent Adult Acute Myeloid Leukemia / Recurrent Disease / Secondary Myelodysplastic Syndromes1
1Active Not RecruitingTreatmentAdult Solid Neoplasm1
1Active Not RecruitingTreatmentAdvanced Ovarian Cancer / Carboplatin / Paclitaxel / Triple Negative Metastatic Breast Cancer1
1Active Not RecruitingTreatmentAdvanced Solid Tumors1
1Active Not RecruitingTreatmentAdvanced Solid Tumors / Metastatic Solid Tumors1
1Active Not RecruitingTreatmentBRCA-mutated Solid Tumor / Triple Negative Metastatic Breast Cancer1
1Active Not RecruitingTreatmentBRCA1 Mutation Carrier / BRCA2 Mutation Carrier / Estrogen Receptor Negative / Estrogen Receptor Positive / HER2/Neu Negative / Male Breast Carcinoma / Progesterone Receptor Negative / Progesterone Receptor Positive / Recurrent Breast Carcinoma / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Stage IV Breast Cancer / Triple-Negative Breast Carcinoma1
1Active Not RecruitingTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor / Liver Cancer / Neuroblastomas / Sarcomas / Testicular germ cell tumour1
1Active Not RecruitingTreatmentCancer of the Urethra / Ureter Cancer / Urethral Cancer / Urethral Neoplasms1
1Active Not RecruitingTreatmentCancer, Breast3
1Active Not RecruitingTreatmentCancer, Breast / Cancer, Ovarian1
1Active Not RecruitingTreatmentCancer, Breast / Cancer, Ovarian / Cervical Cancers / Endometrial Cancers / Fallopian Tube Cancer / Primary Peritoneal Cancer1
1Active Not RecruitingTreatmentCancer, Breast / Cancer, Ovarian / Colon Cancer / Gastric Cancers / Lung Cancers / Tumors, Solid1
1Active Not RecruitingTreatmentCancer, Ovarian1
1Active Not RecruitingTreatmentCancer, Ovarian / Endometrial Cancers1
1Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / No Prior Chemotherapy / Primary Peritoneal Cancer1
1Active Not RecruitingTreatmentCancer, Ovarian / Peritoneal Cavity Cancer1
1Active Not RecruitingTreatmentCancers2
1Active Not RecruitingTreatmentCervical Adenocarcinoma / Cervical Adenosquamous Carcinoma / Cervical Squamous Cell Carcinoma / Stage IB Cervical Cancer / Stage IIA Cervical Cancer / Stage IIB Cervical Cancer / Stage IIIA Cervical Cancer / Stage IIIB Cervical Cancer / Stage IVA Cervical Cancer1
1Active Not RecruitingTreatmentEsophageal Cancers1
1Active Not RecruitingTreatmentFallopian Tube Carcinosarcoma / Fallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Mucinous Adenocarcinoma / Fallopian Tube Serous Neoplasm / Fallopian Tube Transitional Cell Carcinoma / Ovarian Brenner Tumor / Ovarian Carcinosarcoma / Ovarian Clear Cell Adenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mixed Epithelial Tumor / Ovarian Mucinous Adenocarcinoma / Ovarian Seromucinous Tumor / Ovarian Serous Adenocarcinoma / Ovarian Transitional Cell Carcinoma / Primary Peritoneal Serous Adenocarcinoma / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer / Undifferentiated Fallopian Tube Carcinoma / Undifferentiated Ovarian Carcinoma1
1Active Not RecruitingTreatmentFallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Mucinous Adenocarcinoma / Fallopian Tube Serous Adenocarcinoma / Fallopian Tube Transitional Cell Carcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Adenocarcinoma / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Seromucinous Carcinoma / Ovarian Serous Adenocarcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Transitional Cell Carcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Undifferentiated Fallopian Tube Carcinoma / Undifferentiated Ovarian Carcinoma1
1Active Not RecruitingTreatmentHead and Neck Cancers1
1Active Not RecruitingTreatmentLung Cancers1
1Active Not RecruitingTreatmentMale Breast Cancer / Recurrent Breast Cancer / Recurrent Fallopian Tube Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Primary Peritoneal Cavity Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Stage IV Breast Cancer1
1Active Not RecruitingTreatmentMalignant Ovarian Mixed Epithelial Tumor / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Seromucinous Carcinoma / Ovarian Serous Cystadenocarcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Undifferentiated Ovarian Carcinoma1
1Active Not RecruitingTreatmentMelanoma (Skin)1
1Active Not RecruitingTreatmentNeoplasms, Breast1
1Active Not RecruitingTreatmentNeuroblastomas1
1Active Not RecruitingTreatmentNon Small Cell Lung Cancer (NSCLC)1
1Active Not RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)3
1Active Not RecruitingTreatmentRecurrent Non-small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
1Active Not RecruitingTreatmentSquamous Cell Carcinoma of the Head and Neck (SCCHN)2
1Active Not RecruitingTreatmentTumors, Solid1
1Active Not RecruitingTreatmentUnspecified Childhood Solid Tumor, Protocol Specific1
1CompletedNot AvailableCancers1
1CompletedNot AvailableEpithelial Ovarian Cancer1
1CompletedBasic ScienceLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
1CompletedDiagnosticCarcinomas / Non-Small-Cell Lung Carcinoma (NSCLC)1
1CompletedSupportive CareCancers1
1CompletedTreatmentAdenocarcinomas / Non-Small-Cell Lung Carcinoma (NSCLC)1
1CompletedTreatmentAdult Grade III Lymphomatoid Granulomatosis / Adult Nasal Type Extranodal NK/T-Cell Lymphoma / Contiguous Stage II Adult Burkitt Lymphoma / Contiguous Stage II Adult Diffuse Large Cell Lymphoma / Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma / Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma / Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma / Contiguous Stage II Adult Lymphoblastic Lymphoma / Contiguous Stage II Grade 1 Follicular Lymphoma / Contiguous Stage II Grade 2 Follicular Lymphoma / Contiguous Stage II Grade 3 Follicular Lymphoma / Contiguous Stage II Mantle Cell Lymphoma / Contiguous Stage II Marginal Zone Lymphoma / Contiguous Stage II Small Lymphocytic Lymphoma / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Nodal marginal zone B-cell lymphomas / Noncontiguous Stage II Adult Burkitt Lymphoma / Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma / Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma / Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma / Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma / Noncontiguous Stage II Adult Lymphoblastic Lymphoma / Noncontiguous Stage II Grade 1 Follicular Lymphoma / Noncontiguous Stage II Grade 2 Follicular Lymphoma / Noncontiguous Stage II Grade 3 Follicular Lymphoma / Noncontiguous Stage II Mantle Cell Lymphoma / Noncontiguous Stage II Marginal Zone Lymphoma / Noncontiguous Stage II Small Lymphocytic Lymphoma / Peripheral T-Cell Lymphoma (PTCL) / Recurrent Adult Burkitt Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Recurrent Adult Immunoblastic Large Cell Lymphoma / Recurrent Adult Lymphoblastic Lymphoma / Recurrent Grade 1 Follicular Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Recurrent Mantle Cell Lymphoma / Recurrent Marginal Zone Lymphoma / Recurrent Small Lymphocytic Lymphoma / Splenic Marginal Zone Lymphoma / Stage I Adult Burkitt Lymphoma / Stage I Adult Diffuse Large Cell Lymphoma / Stage I Adult Diffuse Mixed Cell Lymphoma / Stage I Adult Diffuse Small Cleaved Cell Lymphoma / Stage I Adult Immunoblastic Large Cell Lymphoma / Stage I Adult Lymphoblastic Lymphoma / Stage I Grade 1 Follicular Lymphoma / Stage I Grade 2 Follicular Lymphoma / Stage I Grade 3 Follicular Lymphoma / Stage I Mantle Cell Lymphoma / Stage I Marginal Zone Lymphoma / Stage I Small Lymphocytic Lymphoma / Stage III Adult Burkitt Lymphoma / Stage III Adult Diffuse Large Cell Lymphoma / Stage III Adult Diffuse Mixed Cell Lymphoma / Stage III Adult Diffuse Small Cleaved Cell Lymphoma / Stage III Adult Immunoblastic Large Cell Lymphoma / Stage III Adult Lymphoblastic Lymphoma / Stage III Grade 1 Follicular Lymphoma / Stage III Grade 2 Follicular Lymphoma / Stage III Grade 3 Follicular Lymphoma / Stage III Mantle Cell Lymphoma / Stage III Marginal Zone Lymphoma / Stage III Small Lymphocytic Lymphoma / Stage IV Adult Burkitt Lymphoma / Stage IV Adult Diffuse Large Cell Lymphoma / Stage IV Adult Diffuse Mixed Cell Lymphoma / Stage IV Adult Diffuse Small Cleaved Cell Lymphoma / Stage IV Adult Immunoblastic Large Cell Lymphoma / Stage IV Adult Lymphoblastic Lymphoma / Stage IV Grade 1 Follicular Lymphoma / Stage IV Grade 2 Follicular Lymphoma / Stage IV Grade 3 Follicular Lymphoma / Stage IV Mantle Cell Lymphoma / Stage IV Marginal Zone Lymphoma / Stage IV Small Lymphocytic Lymphoma / Unspecified Adult Solid Tumor, Protocol Specific / Waldenstrom's Macroglobulinemia (WM)1
1CompletedTreatmentAdult Solid Neoplasm / BRCA1 Mutation Carrier / BRCA2 Mutation Carrier / Hereditary Breast and Ovarian Cancer Syndrome1
1CompletedTreatmentAdult Solid Neoplasm / Estrogen Receptor Negative / Estrogen Receptor Positive / HER2/Neu Negative / Male Breast Carcinoma / Progesterone Receptor Negative / Recurrent Breast Carcinoma / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Stage IV Breast Cancer / Triple-Negative Breast Carcinoma1
1CompletedTreatmentAdvanced Cancers1
1CompletedTreatmentAdvanced Melanoma1
1CompletedTreatmentAdvanced Solid Tumors4
1CompletedTreatmentAdvanced Solid Tumors / Metastatic Solid Tumors1
1CompletedTreatmentAdvanced Solid Tumors / Metastatic Triple Negative Breast Cancer1
1CompletedTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter1
1CompletedTreatmentBrain and Central Nervous System Tumors2
1CompletedTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Childhood Germ Cell Tumor / Kidney Cancer / Liver Cancer / Neuroblastomas / Sarcomas / Unspecified Childhood Solid Tumor, Protocol Specific1
1CompletedTreatmentBrain and Central Nervous System Tumors / Lymphoma NOS / Neuroblastomas / Retinoblastoma1
1CompletedTreatmentBrain and Central Nervous System Tumors / Neurofibromatosis Type 11
1CompletedTreatmentBrain and Central Nervous System Tumors / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentBrenner Tumor / Fallopian Tube Cancer / Ovarian Carcinosarcoma / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mixed Epithelial Carcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Undifferentiated Adenocarcinoma / Primary Peritoneal Cavity Cancer / Stage II Ovarian Epithelial Cancer / Stage III Ovarian Epithelial Cancer / Stage IV Ovarian Epithelial Cancer1
1CompletedTreatmentBrenner Tumor / Fallopian Tube Cancer / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mixed Epithelial Carcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Undifferentiated Adenocarcinoma / Primary Peritoneal Cavity Cancer / Stage II Ovarian Epithelial Cancer / Stage III Ovarian Epithelial Cancer / Stage IV Ovarian Epithelial Cancer1
1CompletedTreatmentCancer, Advanced1
1CompletedTreatmentCancer, Breast / Carcinoma of the Prostate / Melanoma (Skin) / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentCancer, Ovarian / Carcinomas / Fallopian Tube Cancer / Primary Peritoneal Cancer1
1CompletedTreatmentCancer, Ovarian / Endometrial Cancers / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
1CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer1
1CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cancer2
1CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer4
1CompletedTreatmentCancer, Ovarian / Fallopian Tube Neoplasms / Peritoneal Neoplasms1
1CompletedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
1CompletedTreatmentCancers4
1CompletedTreatmentCancers / Chronic Lung Diseases1
1CompletedTreatmentCancers / Endometrial Carcinoma / Non-Small-Cell Lung Carcinoma (NSCLC) / Ovarian Carcinoma1
1CompletedTreatmentCancers / Tumors, Solid1
1CompletedTreatmentCarcinoma of the Prostate1
1CompletedTreatmentCervical Cancers1
1CompletedTreatmentColorectal Cancers / Lung Cancers / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentEndometrial Cancers1
1CompletedTreatmentEsophageal Cancers2
1CompletedTreatmentExtensive Stage Small Cell Lung Cancer1
1CompletedTreatmentExtrahepatic Bile Duct Cancer / Gallbladder Cancer / Gastric Cancers / Liver Cancer / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentFallopian Tube Carcinoma / Infectious Disorder / Neutropenias / Ovarian Carcinosarcoma / Primary Peritoneal Carcinoma / Stage III Ovarian Cancer / Stage IV Ovarian Cancer1
1CompletedTreatmentFallopian Tube Carcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Primary Peritoneal Carcinoma / Stage III Ovarian Cancer / Stage IV Ovarian Cancer / Undifferentiated Ovarian Carcinoma1
1CompletedTreatmentFallopian Tube Neoplasms / Neoplasms, Ovarian / Non-Small-Cell Lung Carcinoma (NSCLC) / Pancreatic Ductal Carcinoma / Peritoneal Neoplasms / Transitional Cell Carcinoma / Tumor Virus Infections / Urinary Bladder Neoplasms1
1CompletedTreatmentGenital Neoplasms, Female1
1CompletedTreatmentGliomas / Medulloblastomas / Neoplasms, Brain1
1CompletedTreatmentHead and Neck Cancers1
1CompletedTreatmentLeukemias / Lymphoma NOS / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentLeukemias / Myelodysplastic Syndromes1
1CompletedTreatmentLeukemias / Neutropenias1
1CompletedTreatmentLeydig Cell Tumor / Ovarian Sarcoma / Ovarian Stromal Cancer / Pseudomyxoma Peritonei / Recurrent Cervical Cancer / Recurrent Endometrial Carcinoma / Recurrent Fallopian Tube Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Ovarian Germ Cell Tumor / Recurrent Primary Peritoneal Cavity Cancer / Recurrent Uterine Sarcoma / Recurrent Vaginal Cancer / Recurrent Vulvar Cancer1
1CompletedTreatmentLocally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIB IV1
1CompletedTreatmentLocally Advanced, Metastatic Solid Tumors1
1CompletedTreatmentLung Cancers6
1CompletedTreatmentLymphoma NOS / Lymphoma, Hodgkins1
1CompletedTreatmentLymphoma NOS / Small Intestine Cancer / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentMalignant Diseases1
1CompletedTreatmentMalignant Pleural Effusions / Recurrent Non-small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
1CompletedTreatmentNeoplasms6
1CompletedTreatmentNeoplasms Malignant1
1CompletedTreatmentNeoplasms, Breast / Solid Tumor Cancers1
1CompletedTreatmentNeoplasms, Esophageal1
1CompletedTreatmentNeuroblastomas2
1CompletedTreatmentNeuroblastomas / Sarcomas / Tumor, Brain / Tumors, Central Nervous System1
1CompletedTreatmentNon Small Cell Lung Cancer (NSCLC)1
1CompletedTreatmentNon Small Cell Lung Carcinoma (NSCLC)1
1CompletedTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
1CompletedTreatmentNon-Small-Cell Lung Cancer (NSCLC)1
1CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)7
1CompletedTreatmentNon-Squamous Non-Small Cell Lung Cancer1
1CompletedTreatmentOvarian Sarcoma / Ovarian Stromal Cancer / Recurrent Endometrial Carcinoma / Recurrent Ovarian Epithelial Cancer / Recurrent Ovarian Germ Cell Tumor / Stage III Endometrial Carcinoma / Stage III Ovarian Epithelial Cancer / Stage III Ovarian Germ Cell Tumor / Stage IV Endometrial Carcinoma / Stage IV Ovarian Epithelial Cancer / Stage IV Ovarian Germ Cell Tumor / Unspecified Adult Solid Tumor, Protocol Specific1
1CompletedTreatmentRecurrent Gliomas1
1CompletedTreatmentSmall Cell Lung Carcinoma1
1CompletedTreatmentSolid Cancers2
1CompletedTreatmentSolid Tumor Cancers1
1CompletedTreatmentStage IIIA Non-Small Cell Lung Cancer1
1CompletedTreatmentTumors1
1CompletedTreatmentTumors, Solid5
1CompletedTreatmentUnspecified Adult Solid Tumor, Protocol Specific11
1CompletedTreatmentUnspecified Childhood Solid Tumor, Protocol Specific1
1Not Yet RecruitingTreatmentCarcinoma of the Lungs / Lungcancer1
1Not Yet RecruitingTreatmentEsophageal Cancers1
1RecruitingDiagnosticEsophageal Cancers1
1RecruitingTreatmentAdult Anaplastic Astrocytoma / Adult Anaplastic Oligodendroglioma / Recurrent Adult Brain Tumor1
1RecruitingTreatmentAdvanced Cancers2
1RecruitingTreatmentAdvanced Malignancies / Cancer, Advanced1
1RecruitingTreatmentAdvanced Solid Tumors1
1RecruitingTreatmentAdvanced Solid Tumors / Lymphoma NOS / Tumors, Solid1
1RecruitingTreatmentAdvanced Solid Tumours1
1RecruitingTreatmentBladder Carcinoma / Carcinoma of Unknown Primary Origin / Carcinoma, Breast / Endometrial Carcinoma / Esophageal Carcinoma / Lung Carcinoma / Malignant Head and Neck Neoplasm / Melanoma / Neoplasms, Ovarian / Ovarian Carcinoma / Renal Pelvis and Ureter Urothelial Carcinoma / Testicular Lymphoma / Urethral Carcinoma1
1RecruitingTreatmentBreast Cancer Triple Negative / Cancer, Ovarian / Cervical Cancers / Endometrial Cancers / Tumors, Solid1
1RecruitingTreatmentCD20 Positive / Recurrent Diffuse Large B-Cell Lymphoma / Refractory Diffuse Large B-Cell Lymphoma1
1RecruitingTreatmentCancer of the Esophagus, Gastroesophageal Junction or Stomach1
1RecruitingTreatmentCancer, Advanced1
1RecruitingTreatmentCancer, Advanced / Cancer, Breast / Cancer, Ovarian1
1RecruitingTreatmentCancer, Breast / Cancer, Ovarian / Carcinoma of the Prostate / Carcinoma, Colorectal / Carcinoma, Pancreatic / Melanoma / Non-Small Cell Lung Carcinoma (NSCLC) / Renal Cell Carcinoma (RCC) / Tumors, Solid1
1RecruitingTreatmentCancer, Breast / Cholangiocarcinomas / Colon Cancer / Soft Tissue Sarcoma (STS) / Tumors, Solid1
1RecruitingTreatmentCancer, Breast / Colorectal Cancers / Esophagogastric Cancer / Non-Small-Cell Lung Carcinoma (NSCLC) / Pancreatic Cancers / Tumors1
1RecruitingTreatmentCancer, Breast / Endometrial Cancers / Head and Neck (HNSCC) / Non-Small-Cell Lung Carcinoma (NSCLC) / Ovary Cancer / Small Cell Lung Cancer (SCLC)1
1RecruitingTreatmentCancer, Ovarian3
1RecruitingTreatmentCancer, Ovarian / Endometrial Cancers1
1RecruitingTreatmentCancers1
1RecruitingTreatmentCarcinoma, Squamous Cell of Head and Neck / Esophagogastric Junction Neoplasms / Fallopian Tube Neoplasms / Neoplasms, Ovarian / Peritoneal Neoplasms / Small Cell Lung Carcinoma / Stomach Neoplasms / Triple Negative Breast Neoplasms1
1RecruitingTreatmentCervical Cancers / Precancerous Conditions1
1RecruitingTreatmentDiffuse Large B-Cell Lymphoma (DLBCL)2
1RecruitingTreatmentEndometrial Cancers / Epithelial Ovarian Cancer / Fallopian Tube Cancer / Primary Peritoneal Cancer1
1RecruitingTreatmentEpithelial Ovarian Cancer1
1RecruitingTreatmentFallopian Tube Carcinoma / FIGO Stage IIC-IV Ovarian Carcinoma / Peritoneal Carcinoma1
1RecruitingTreatmentFallopian Tube Cancer / Peritoneal Cavity Cancer / Recurrent Ovarian Epithelial Cancer1
1RecruitingTreatmentHER2 Positive Breast Cancers1
1RecruitingTreatmentHigh-risk Tumor / Lymphoma NOS / Neuroblastomas1
1RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections / Recurrent Anal Cancer / Recurrent Breast Cancer / Recurrent Esophageal Cancer / Recurrent Gastric Cancer / Recurrent Metastatic Squamous Neck Cancer With Occult Primary / Recurrent Non-small Cell Lung Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Salivary Gland Cancer / Recurrent Squamous Cell Carcinoma of the Hypopharynx / Recurrent Squamous Cell Carcinoma of the Larynx / Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity / Recurrent Squamous Cell Carcinoma of the Nasopharynx / Recurrent Squamous Cell Carcinoma of the Oropharynx / Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity / Recurrent Verrucous Carcinoma of the Larynx / Recurrent Verrucous Carcinoma of the Oral Cavity / Salivary Gland Squamous Cell Carcinoma / Stage IV Anal Cancer / Stage IV Breast Cancer / Stage IV Esophageal Cancer / Stage IV Gastric Cancer / Stage IV Non-Small Cell Lung Cancer / Stage IV Ovarian Epithelial Cancer / Stage IV Salivary Gland Cancer / Stage IV Squamous Cell Carcinoma of the Hypopharynx / Stage IV Squamous Cell Carcinoma of the Larynx / Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity / Stage IV Squamous Cell Carcinoma of the Nasopharynx / Stage IV Squamous Cell Carcinoma of the Oropharynx / Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity / Stage IV Verrucous Carcinoma of the Larynx / Stage IV Verrucous Carcinoma of the Oral Cavity / Unspecified Adult Solid Tumor, Protocol Specific1
1RecruitingTreatmentLung Cancers1
1RecruitingTreatmentLymphoma NOS1
1RecruitingTreatmentNeoplasms, Breast / Neoplasms, Pancreatic1
1RecruitingTreatmentNeoplasms, Malignant / Tumors, Solid1
1RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1RecruitingTreatmentRecurrent Ovarian Cancer1
1RecruitingTreatmentRecurrent Salivary Gland Cancer / Recurrent Squamous Cell Carcinoma of the Hypopharynx / Recurrent Squamous Cell Carcinoma of the Larynx / Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity / Recurrent Squamous Cell Carcinoma of the Nasopharynx / Recurrent Squamous Cell Carcinoma of the Oropharynx / Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity / Recurrent Verrucous Carcinoma of the Larynx / Recurrent Verrucous Carcinoma of the Oral Cavity / Salivary Gland Squamous Cell Carcinoma / Tongue Cancer1
1RecruitingTreatmentSmall Cell Lung Cancer (SCLC)1
1RecruitingTreatmentSolid Neoplasms1
1RecruitingTreatmentStage II Non-Small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1RecruitingTreatmentStage IIA Non-small Cell Lung Cancer / Stage IIB Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1RecruitingTreatmentStage IV Non-Small Cell Lung Cancer1
1RecruitingTreatmentTriple Negative Breast Neoplasms1
1SuspendedTreatmentBone Marrow Suppression / Brain and Central Nervous System Tumors / Drug/Agent Toxicity by Tissue/Organ / Long-Term Effects Secondary to Cancer Therapy in Children1
1SuspendedTreatmentBreast Cancer - Female / Unspecified Adult Solid Tumor - Protocol Specific1
1SuspendedTreatmentCancers1
1SuspendedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1SuspendedTreatmentRecurrent Non-Small Cell Lung Carcinoma / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1TerminatedTreatmentAdenocarcinoma of the Lung / Bronchoalveolar Cell Lung Cancer / Large Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1TerminatedTreatmentAdenocarcinoma of the Lung / Bronchoalveolar Cell Lung Cancer / Large Cell Lung Cancer / Stage II Non-Small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1TerminatedTreatmentAdenocarcinomas / Esophageal Cancers / Neoplasms, Esophageal / Squamous Cell Carcinoma (SCC)1
1TerminatedTreatmentBladder Cancers / Tumors, Solid1
1TerminatedTreatmentCancer, Advanced1
1TerminatedTreatmentCancer, Breast1
1TerminatedTreatmentCancer, Ovarian / Carcinomas / Neoplasms, Ovarian / Ovarian Diseases1
1TerminatedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
1TerminatedTreatmentCancer: Solid Tumors1
1TerminatedTreatmentCervical Cancers1
1TerminatedTreatmentEstrogen Receptor Negative / HER2/Neu Negative / Progesterone Receptor Negative / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Carcinoma1
1TerminatedTreatmentFallopian Tube Neoplasms / Neoplasms, Ovarian / Peritoneal Neoplasms1
1TerminatedTreatmentFallopian Tube Neoplasms / Neoplasms / Neoplasms, Ovarian / Primary Peritoneal Neoplasms1
1TerminatedTreatmentLung Cancers / Unspecified Adult Solid Tumor, Protocol Specific1
1TerminatedTreatmentLymphoma, B-Cell / Non-Hodgkin's Lymphoma (NHL)1
1TerminatedTreatmentMetastatic Cancers1
1TerminatedTreatmentNeoplasms1
1TerminatedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1TerminatedTreatmentNonsmall Cell Lung Cancer Stage III / Nonsquamous Nonsmall Cell Neoplasm of Lung1
1TerminatedTreatmentTumors, Solid1
1TerminatedTreatmentUnspecified Adult Solid Tumor, Protocol Specific1
1WithdrawnTreatmentAdenocarcinoma of the Lung / Large Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IIA Non-small Cell Lung Cancer / Stage IIB Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1WithdrawnTreatmentCancer of Cervix / Tumors1
1WithdrawnTreatmentCancers / Epithelial Ovarian Cancer / Non Small Cell Lung Cancer (NSCLC)1
1WithdrawnTreatmentChemotherapeutic Agent Toxicity / Lung Cancers1
1WithdrawnTreatmentNeoplasms1
1WithdrawnTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1WithdrawnTreatmentOvarian Papillary Serous Carcinoma / Ovarian Serous Cystadenocarcinoma / Recurrent Fallopian Tube Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Ovarian Germ Cell Tumor / Recurrent Primary Peritoneal Cavity Cancer1
1WithdrawnTreatmentTumors1
1, 2Active Not RecruitingTreatmentAdenocarcinomas / Tumors / Unknown Primary Tumors1
1, 2Active Not RecruitingTreatmentBasaloid Squamous Cell Carcinoma / Carcinoma, Adenosquamous Cell / Carcinoma, Undifferentiated / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1
1, 2Active Not RecruitingTreatmentBrain and Central Nervous System Tumors1
1, 2Active Not RecruitingTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor / Kidney Cancer / Liver Cancer / Lymphoma NOS / Neuroblastomas / Sarcomas / Testicular germ cell tumour / Unspecified Childhood Solid Tumor, Protocol Specific1
1, 2Active Not RecruitingTreatmentCancer, Breast6
1, 2Active Not RecruitingTreatmentCancer, Ovarian2
1, 2Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer1
1, 2Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
1, 2Active Not RecruitingTreatmentCarcinoma of the Prostate1
1, 2Active Not RecruitingTreatmentCervix Carcinoma Recurrent / Metastatic Carcinoma to the Uterine Cervix / Recurrent Carcinoma Cervix1
1, 2Active Not RecruitingTreatmentChemonaive / Extensive Stage Lung Cancer / Small Cell Lung Cancer (SCLC)1
1, 2Active Not RecruitingTreatmentEsophageal Cancers / Neoplasms, Esophageal1
1, 2Active Not RecruitingTreatmentExtensive Stage Small Cell Lung Cancer / Recurrent Small Cell Lung Cancer1
1, 2Active Not RecruitingTreatmentGlioblastoma Multiforme1
1, 2Active Not RecruitingTreatmentLung Cancers1
1, 2Active Not RecruitingTreatmentLymphoma, Hodgkins1
1, 2Active Not RecruitingTreatmentNon Small Cell Lung Cancer (NSCLC)1
1, 2Active Not RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1, 2Active Not RecruitingTreatmentRecurrent Adult Diffuse Large Cell Lymphoma / Recurrent Adult Hodgkin's Lymphoma1
1, 2Active Not RecruitingTreatmentRecurrent Glioblastoma Multiforme (rGBM)1
1, 2Active Not RecruitingTreatmentRecurrent Platinum-resistant Ovarian Cancer1
1, 2Active Not RecruitingTreatmentSmall Cell Lung Cancer (SCLC)1
1, 2Active Not RecruitingTreatmentSmall Cell Lung Carcinoma1
1, 2Active Not RecruitingTreatmentSquamous Cell Carcinoma of the Head and Neck (SCCHN)1
1, 2Active Not RecruitingTreatmentStage III Ovarian Cancer / Stage IV Ovarian Cancer / Uterine Cancers1
1, 2CompletedPreventionCancer, Advanced / Tumors, Solid1
1, 2CompletedTreatmentAdult Nasal Type Extranodal NK/T-Cell Lymphoma / Anaplastic Large Cell Lymphoma / Angioimmunoblastic T-Cell Lymphoma / Contiguous Stage II Mantle Cell Lymphoma / Cutaneous B-Cell Non-Hodgkin Lymphoma / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Nodal marginal zone B-cell lymphomas / Noncontiguous Stage II Mantle Cell Lymphoma / Recurrent Adult Burkitt Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Recurrent Adult Hodgkin's Lymphoma / Recurrent Adult Immunoblastic Large Cell Lymphoma / Recurrent Adult Lymphoblastic Lymphoma / Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma / Recurrent Grade 1 Follicular Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Recurrent Mantle Cell Lymphoma / Recurrent Marginal Zone Lymphoma / Recurrent Mycosis Fungoides/Sezary Syndrome / Recurrent Small Lymphocytic Lymphoma / Splenic Marginal Zone Lymphoma / Stage I Cutaneous T-cell Non-Hodgkin Lymphoma / Stage I Mantle Cell Lymphoma / Stage I Mycosis Fungoides/Sezary Syndrome / Stage II Cutaneous T-cell Non-Hodgkin Lymphoma / Stage II Mycosis Fungoides/Sezary Syndrome / Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma / Stage III Mantle Cell Lymphoma / Stage III Mycosis Fungoides/Sezary Syndrome / Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma / Stage IV Mantle Cell Lymphoma / Stage IV Mycosis Fungoides/Sezary Syndrome / Waldenstrom's Macroglobulinemia (WM)1
1, 2CompletedTreatmentBladder Cancers / Cancer, Ovarian / Epithelial Ovarian Cancer / Fallopian Tube Cancer1
1, 2CompletedTreatmentBrain and Central Nervous System Tumors1
1, 2CompletedTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Extragonadal Germ Cell Tumor / Teratoma / Testicular germ cell tumour1
1, 2CompletedTreatmentBreast / Cancers1
1, 2CompletedTreatmentCancer, Breast3
1, 2CompletedTreatmentCancer, Ovarian4
1, 2CompletedTreatmentCancer, Ovarian / Cervical Cancers / Endometrial Cancers / Fallopian Tube Cancer / Sarcomas1
1, 2CompletedTreatmentCancer, Ovarian / Extragonadal Germ Cell Tumor / Testicular germ cell tumour2
1, 2CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cavity Cancer1
1, 2CompletedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
1, 2CompletedTreatmentCancers1
1, 2CompletedTreatmentCancers of the Head and Neck / Neoplasms, Head and Neck1
1, 2CompletedTreatmentCarcinoma of the Prostate1
1, 2CompletedTreatmentCervical Cancers1
1, 2CompletedTreatmentChronic Myeloproliferative Disorders / Leukemias / Lymphoma NOS / Multiple Myeloma and Plasma Cell Neoplasm / Myelodysplastic Syndromes / Precancerous/Nonmalignant Condition / Unspecified Adult Solid Tumor, Protocol Specific1
1, 2CompletedTreatmentEsophageal Cancers / Extrahepatic Bile Duct Cancer / Gastric Cancers / Head and Neck Cancers / Liver Cancer / Unspecified Adult Solid Tumor, Protocol Specific1
1, 2CompletedTreatmentExtensive-Stage Small Cell Lung Cancer1
1, 2CompletedTreatmentExtensive-Stage Small Cell Lung Cancer / Lung Cancers / Small Cell Lung Cancer (SCLC) / Tumors, Solid1
1, 2CompletedTreatmentHead and Neck Cancers3
1, 2CompletedTreatmentLung Cancers5
1, 2CompletedTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
1, 2CompletedTreatmentLymphoma NOS2
1, 2CompletedTreatmentMetastases, Brain / Tumor, Brain1
1, 2CompletedTreatmentNon-Small-Cell Lung Cancer (NSCLC)1
1, 2CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)5
1, 2CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC) / Tumors, Solid1
1, 2CompletedTreatmentOvarian Epithelial Cancer Stage III / Stage IV Breast Cancer / Stage IV Ovarian Cancer1
1, 2CompletedTreatmentPediatric Solid Tumors1
1, 2CompletedTreatmentRecurrent Adult Diffuse Large Cell Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Recurrent Mantle Cell Lymphoma1
1, 2CompletedTreatmentRecurrent Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1, 2CompletedTreatmentRecurrent Ovarian Cancer1
1, 2CompletedTreatmentSmall Cell Lung Cancer (SCLC)2
1, 2CompletedTreatmentStage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
1, 2CompletedTreatmentStage IV Non-Small Cell Lung Cancer1
1, 2Not Yet RecruitingTreatmentCancers1
1, 2Not Yet RecruitingTreatmentEsophageal Cancers1
1, 2Not Yet RecruitingTreatmentFallopian Tube Carcinosarcoma / Fallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Serous Neoplasm / High Grade Ovarian Serous Adenocarcinoma / Ovarian Carcinosarcoma / Ovarian Clear Cell Adenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Primary Peritoneal Serous Adenocarcinoma / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer1
1, 2Not Yet RecruitingTreatmentHormone-Resistant Prostate Cancer / Metastatic Prostate Carcinoma / Recurrent Prostate Carcinoma / Stage IV Prostate Cancer1
1, 2Not Yet RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1, 2RecruitingPreventionNon-Small-Cell Lung Carcinoma (NSCLC)1
1, 2RecruitingTreatmentAdenocarcinoma of the Lung / Bronchioloalveolar Carcinoma / Large Cell Lung Carcinoma / Lung Adenocarcinoma, Mixed Subtype / Squamous Cell Lung Carcinoma / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
1, 2RecruitingTreatmentAdult Anaplastic Oligodendroglioma / Adult Mixed Glioma / Adult Oligodendroglioma / Oligoastrocytoma / Recurrent Adult Brain Neoplasm1
1, 2RecruitingTreatmentAnaplastic Astrocytoma (AA) / Brainstem Glioma / Diffuse Intrinsic Pontine Glioma (DIPG) / DIPG / Glioblastoma Multiforme / Glioma, Astrocytic / Gliosarcoma / Low-Grade Gliomas / Optic Nerve Glioma / Pilocytic Astrocytoma / Pilomyxoid Astrocytoma / Pleomorphic Xanthoastrocytoma1
1, 2RecruitingTreatmentB-Cell Malignancies1
1, 2RecruitingTreatmentCancer, Breast2
1, 2RecruitingTreatmentCancer, Ovarian1
1, 2RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
1, 2RecruitingTreatmentCentral Nervous System Embryonal Tumor / Germ Cell Tumors1
1, 2RecruitingTreatmentCentral Nervous System Lymphoma1
1, 2RecruitingTreatmentCervical Carcinoma / Endometrial Carcinoma / Fallopian Tube Carcinoma / Ovarian Carcinoma / Primary Peritoneal Carcinoma1
1, 2RecruitingTreatmentContiguous Stage II Adult Diffuse Large Cell Lymphoma / Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Stage I Adult Diffuse Large Cell Lymphoma / Stage III Adult Diffuse Large Cell Lymphoma / Stage IV Adult Diffuse Large Cell Lymphoma1
1, 2RecruitingTreatmentDiffuse Large B-Cell Lymphoma (DLBCL) / Recurrent Diffuse Large B-Cell Lymphoma / Recurrent Mediastinal (Thymic) Large B-Cell Cell Lymphoma / Refractory Diffuse Large B-Cell Lymphoma / Refractory Mediastinal (Thymic) Large B-Cell Cell Lymphoma / Transformed Recurrent Non-Hodgkin Lymphoma1
1, 2RecruitingTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Primary Peritoneal Cancer1
1, 2RecruitingTreatmentExtensive-Stage Small-Cell Lung Cancer1
1, 2RecruitingTreatmentGlioblastomas / Gliomas / Tumor, Brain1
1, 2RecruitingTreatmentHigh-risk Medulloblastoma1
1, 2RecruitingTreatmentNeoplasms, Head and Neck1
1, 2RecruitingTreatmentNon-Hodgkin's Lymphoma (NHL)1
1, 2RecruitingTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
1, 2RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)2
1, 2RecruitingTreatmentPlatinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p531
1, 2RecruitingTreatmentRecurrent Adult Hodgkin's Lymphoma / Refractory Hodgkin Lymphoma1
1, 2RecruitingTreatmentSmall Cell Lung Cancer (SCLC)1
1, 2SuspendedTreatmentAnaplastic Astrocytoma (AA) / Glioblastoma Multiforme1
1, 2SuspendedTreatmentHead and Neck Squamous Cell Carcinoma (HNSCC) / Human Papillomavirus Infections / Salivary Gland Squamous Cell Carcinoma / Stage IVA Hypopharyngeal Squamous Cell Carcinoma / Stage IVA Laryngeal Squamous Cell Carcinoma / Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma / Stage IVA Major Salivary Gland Carcinoma / Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Stage IVA Oropharyngeal Carcinoma / Stage IVA Oropharyngeal Squamous Cell Carcinoma / Stage IVB Hypopharyngeal Squamous Cell Carcinoma / Stage IVB Laryngeal Squamous Cell Carcinoma / Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma / Stage IVB Major Salivary Gland Carcinoma / Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Stage IVB Oropharyngeal Carcinoma / Stage IVB Oropharyngeal Squamous Cell Carcinoma / Tongue Carcinoma1
1, 2TerminatedNot AvailableNon-Small-Cell Lung Carcinoma (NSCLC)1
1, 2TerminatedTreatmentAdvanced Lung Cancer / Non Small Cell Lung Cancer (NSCLC)1
1, 2TerminatedTreatmentAdvanced Squamous Non-Small Cell Lung Cancer1
1, 2TerminatedTreatmentAnaplastic Large Cell Lymphoma / Recurrent Childhood Anaplastic Large Cell Lymphoma1
1, 2TerminatedTreatmentCancer, Ovarian2
1, 2TerminatedTreatmentEsophageal Cancers / Gastric Cancers / Tumors1
1, 2TerminatedTreatmentExtensive Stage Unresectable / Non-Small-Cell Lung Carcinoma (NSCLC)1
1, 2TerminatedTreatmentGlioblastoma Multiforme1
1, 2TerminatedTreatmentHER-2 Positive Breast Cancer1
1, 2TerminatedTreatmentHead and Neck Cancers1
1, 2TerminatedTreatmentLocally Advanced Non-Small Cell Lung Cancer1
1, 2TerminatedTreatmentLung Cancers4
1, 2TerminatedTreatmentMesothelioma1
1, 2TerminatedTreatmentNeoplasms1
1, 2TerminatedTreatmentNon-Small Cell Lunch Cancer / Non-Small-Cell Lung Carcinoma (NSCLC)1
1, 2TerminatedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
1, 2TerminatedTreatmentNon-Squamous Non-Small Cell Lung Cancer / Squamous Non-Small Cell Lung Cancer1
1, 2TerminatedTreatmentSmall Cell Lung Carcinoma1
1, 2TerminatedTreatmentStage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
1, 2WithdrawnTreatmentBrain and Central Nervous System Tumors1
1, 2WithdrawnTreatmentBrain and Central Nervous System Tumors / Cancer, Breast / Cognitive/Functional Effects / Drug/Agent Toxicity by Tissue/Organ / Psychosocial Effects of Cancer and Its Treatment1
1, 2WithdrawnTreatmentCancer of the Breast1
1, 2WithdrawnTreatmentCancer, Ovarian1
1, 2WithdrawnTreatmentLung Cancers1
1, 2WithdrawnTreatmentLymphoma NOS1
1, 2WithdrawnTreatmentLymphoma NOS / Lymphoma, Hodgkins / Non-Hodgkin's Lymphoma (NHL)1
2Active Not RecruitingNot AvailableRecurrent Non-small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2Active Not RecruitingDiagnosticLung Cancers1
2Active Not RecruitingPreventionCancer, Ovarian / Endometrial Cancers / Uterine Cervical Cancer1
2Active Not RecruitingTreatmentAdenocarcinoma of the Lung / Adenosquamous Lung Carcinoma / Bronchioloalveolar Carcinoma / Malignant Pericardial Effusion / Malignant Pleural Effusions / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2Active Not RecruitingTreatmentAdenocarcinoma of the Lung / Bronchioloalveolar Carcinoma / Large Cell Lung Carcinoma / Recurrent Non-Small Cell Lung Carcinoma / Stage IV Non-Small Cell Lung Cancer1
2Active Not RecruitingTreatmentAdenocarcinomas of the Gastroesophageal Junction / Esophageal Cancers1
2Active Not RecruitingTreatmentAdvanced Non-Small Cell Lung Cancer / Non-Small-Cell Lung Carcinoma (NSCLC) / Recurrent Non-small Cell Lung Cancer1
2Active Not RecruitingTreatmentAdvanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma / Non-Hodgkin's Lymphoma (NHL)1
2Active Not RecruitingTreatmentAnaplastic Astrocytoma (AA) / Anaplastic Mixed Oligoastrocytoma / Anaplastic Oligodendroglioma (AO) / Glioblastoma Multiforme / Gliosarcoma1
2Active Not RecruitingTreatmentBRCA1 Mutation Carrier / BRCA2 Mutation Carrier / Recurrent Breast Carcinoma / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Stage IV Breast Cancer1
2Active Not RecruitingTreatmentBladder Cancers1
2Active Not RecruitingTreatmentBladder Cancers / Brain and Central Nervous System Tumors / Cancer, Ovarian / Carcinoma of Unknown Primary / Extragonadal Germ Cell Tumor / Head and Neck Cancers / Kidney Cancer / Lung Cancers / Sarcomas / Testicular germ cell tumour / Unspecified Adult Solid Tumor, Protocol Specific1
2Active Not RecruitingTreatmentBrain and Central Nervous System Tumors1
2Active Not RecruitingTreatmentBrain and Central Nervous System Tumors / Neuroblastomas1
2Active Not RecruitingTreatmentCancer, Breast12
2Active Not RecruitingTreatmentCancer, Breast / HER2-Negative Breast Cancer / HER2-positive Breast Cancer / Recurrent Breast Cancer / Stage IA Breast Cancer / Stage IB Breast Cancer / Stage II Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer1
2Active Not RecruitingTreatmentCancer, Breast / Metastatic Breast Cancer (MBC) / Progressive Breast Cancer1
2Active Not RecruitingTreatmentCancer, Ovarian6
2Active Not RecruitingTreatmentCancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor / Testicular germ cell tumour1
2Active Not RecruitingTreatmentCancer, Ovarian / Endometrial Cancers / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
2Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Metastatic Cancers / Peritoneal Cavity Cancer1
2Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cancer1
2Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer2
2Active Not RecruitingTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
2Active Not RecruitingTreatmentCarcinoma, Squamous Cell of Head and Neck1
2Active Not RecruitingTreatmentCarcinomas1
2Active Not RecruitingTreatmentCervical Cancers2
2Active Not RecruitingTreatmentChemotherapeutic Agent Toxicity / Head and Neck Cancers / Mucositis / Radiation Toxicity / Xerostomia1
2Active Not RecruitingTreatmentChildhood Extracranial Germ Cell Tumor / Childhood Extragonadal Germ Cell Tumor / Childhood Malignant Ovarian Germ Cell Tumor / Childhood Malignant Testicular Germ Cell Tumor / Ovarian Choriocarcinoma / Ovarian Embryonal Carcinoma / Ovarian Yolk Sac Tumor / Recurrent Childhood Malignant Germ Cell Tumor / Recurrent Malignant Testicular Germ Cell Tumor / Recurrent Ovarian Germ Cell Tumor / Testicular Choriocarcinoma / Testicular Choriocarcinoma and Embryonal Carcinoma / Testicular Choriocarcinoma and Yolk Sac Tumor / Testicular Embryonal Carcinoma / Testicular Embryonal Carcinoma and Yolk Sac Tumor / Testicular Yolk Sac Tumor1
2Active Not RecruitingTreatmentChildhood Germ Cell Tumor / Tumor, Brain / Tumors, Central Nervous System1
2Active Not RecruitingTreatmentEndometrial Adenocarcinomas / Endometrial Adenosquamous Carcinoma / Endometrial Clear Cell Adenocarcinoma / Endometrial Serous Adenocarcinoma / Recurrent Uterine Corpus Carcinoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
2Active Not RecruitingTreatmentEndometrial Cancers1
2Active Not RecruitingTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Primary Peritoneal Carcinoma1
2Active Not RecruitingTreatmentErbB2-Positive Stage I-III Breast Cancer1
2Active Not RecruitingTreatmentEsophageal Cancers2
2Active Not RecruitingTreatmentEstrogen Receptor-negative Breast Cancer / HER2-Negative Breast Cancer / Male Breast Cancer / Progesterone Receptor-negative Breast Cancer / Stage IA Breast Cancer / Stage IB Breast Cancer / Stage II Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Cancer (TNBC)1
2Active Not RecruitingTreatmentExtensive Stage Small Cell Lung Carcinoma1
2Active Not RecruitingTreatmentHER-2 Positive Breast Cancer1
2Active Not RecruitingTreatmentHead and Neck Cancers3
2Active Not RecruitingTreatmentHead and Neck Cancers / Squamous Cell Carcinoma (SCC)1
2Active Not RecruitingTreatmentHead and Neck Cancers / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1
2Active Not RecruitingTreatmentHead and Neck Squamous Cell Carcinoma (HNSCC)1
2Active Not RecruitingTreatmentHigh Risk Supratentorial PNET / Metastatic Medulloblastoma / Metastatic PNET1
2Active Not RecruitingTreatmentKidney Cancer1
2Active Not RecruitingTreatmentLeukemias1
2Active Not RecruitingTreatmentLiver Cancer1
2Active Not RecruitingTreatmentLiver Metastasis / Nasopharyngeal Cancers / Non Small Cell Lung Cancer (NSCLC)1
2Active Not RecruitingTreatmentLung Cancers16
2Active Not RecruitingTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
2Active Not RecruitingTreatmentLymphoma NOS1
2Active Not RecruitingTreatmentLymphoma, Hodgkins1
2Active Not RecruitingTreatmentMelanoma (Skin)1
2Active Not RecruitingTreatmentMetastatic Breast Cancer (MBC)3
2Active Not RecruitingTreatmentMetastatic Malignant Neoplasm in the Brain / Recurrent Non-Small Cell Lung Carcinoma / Stage IIA Non-Small Cell Lung Carcinoma / Stage IIB Non-Small Cell Lung Carcinoma / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2Active Not RecruitingTreatmentMetastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma / Recurrent Metastatic Squamous Neck Cancer With Occult Primary / Recurrent Salivary Gland Cancer / Recurrent Squamous Cell Carcinoma of the Hypopharynx / Recurrent Squamous Cell Carcinoma of the Larynx / Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity / Recurrent Squamous Cell Carcinoma of the Nasopharynx / Recurrent Squamous Cell Carcinoma of the Oropharynx / Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity / Recurrent Verrucous Carcinoma of the Larynx / Recurrent Verrucous Carcinoma of the Oral Cavity / Salivary Gland Squamous Cell Carcinoma / Stage IV Salivary Gland Cancer / Stage IV Squamous Cell Carcinoma of the Hypopharynx / Stage IV Squamous Cell Carcinoma of the Larynx / Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity / Stage IV Squamous Cell Carcinoma of the Nasopharynx / Stage IV Squamous Cell Carcinoma of the Oropharynx / Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity / Stage IV Verrucous Carcinoma of the Larynx / Stage IV Verrucous Carcinoma of the Oral Cavity / Tongue Cancer / Untreated Metastatic Squamous Neck Cancer With Occult Primary1
2Active Not RecruitingTreatmentNeoplasms, Breast1
2Active Not RecruitingTreatmentNeoplasms, Ovarian1
2Active Not RecruitingTreatmentNeoplasms, Ovarian / Ovarian Cancer (OvCa) / Ovarian Epithelial Cancer1
2Active Not RecruitingTreatmentNeoplasms, Ovarian / Ovarian Epithelial Cancer1
2Active Not RecruitingTreatmentNeuroblastomas1
2Active Not RecruitingTreatmentNeuroendocrine Carcinoma of the Skin1
2Active Not RecruitingTreatmentNon Small Cell Lung Cancer (NSCLC)2
2Active Not RecruitingTreatmentNon-Hodgkin's Lymphoma (NHL)2
2Active Not RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)6
2Active Not RecruitingTreatmentNon-Squamous Non-Small Cell Lung Cancer2
2Active Not RecruitingTreatmentNonsquamous Nonsmall Cell Neoplasm of Lung1
2Active Not RecruitingTreatmentPancreatic Acinar Cell Carcinoma / Pancreatic Ductal Adenocarcinoma / Recurrent Pancreatic Carcinoma / Stage IV Pancreatic Cancer1
2Active Not RecruitingTreatmentProsthesis Survival1
2Active Not RecruitingTreatmentRecurrent Bladder Cancer / Stage IV Bladder Cancer / Transitional Cell Carcinoma of the Bladder1
2Active Not RecruitingTreatmentRetinal Neoplasms / Retinoblastoma1
2Active Not RecruitingTreatmentRetinoblastoma1
2Active Not RecruitingTreatmentSarcomas1
2Active Not RecruitingTreatmentSquamous Cell Carcinoma (SCC)1
2Active Not RecruitingTreatmentSquamous Non Small Cell Lung Cancer1
2Active Not RecruitingTreatmentStage IIIB or IV Non-Small Cell Lung Cancer1
2Active Not RecruitingTreatmentTumor, Brain / Tumors, Central Nervous System1
2Active Not RecruitingTreatmentUntreated Stage III Melanoma or Stage IV Melanoma1
2CompletedNot AvailableTumors, Solid1
2CompletedSupportive CareCancer, Ovarian / Lung Cancers / Neurotoxicity1
2CompletedSupportive CareCancers / Chemotherapy-Induced Thrombocytopenia / Lung Cancers / Neoplasms, Lung / Non-Small-Cell Lung Carcinoma (NSCLC) / Oncology / Thrombocytopenias / Tumors, Solid1
2CompletedTreatmentAcinar Cell Adenocarcinoma of the Pancreas / Duct Cell Adenocarcinoma of the Pancreas / Stage IV Pancreatic Cancer1
2CompletedTreatmentAdenocarcinoma of the Lung / Adenosquamous Cell Lung Cancer / Bronchoalveolar Cell Lung Cancer / Large Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
2CompletedTreatmentAdenocarcinoma, Prostate1
2CompletedTreatmentAdenocarcinomas / Esophageal Cancers / Gastro-esophageal Junction Cancer / Squamous Cell Carcinoma (SCC)1
2CompletedTreatmentAdenocarcinomas / Non-Small-Cell Lung Carcinoma (NSCLC)1
2CompletedTreatmentAdenosquamous Cell Lung Cancer / Drug/Agent Toxicity by Tissue/Organ / Hemoptysis / Squamous Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2CompletedTreatmentAdult Acute Megakaryoblastic Leukemia (M7) / Adult Acute Minimally Differentiated Myeloid Leukemia (M0) / Adult Acute Monoblastic Leukemia (M5a) / Adult Acute Monocytic Leukemia (M5b) / Adult Acute Myeloblastic Leukemia With Maturation (M2) / Adult Acute Myeloblastic Leukemia Without Maturation (M1) / Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities / Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) / Adult Acute Myeloid Leukemia With T(16;16)(p13;q22) / Adult Acute Myeloid Leukemia With T(8;21)(q22;q22) / Adult Acute Myelomonocytic Leukemia (M4) / Adult Erythroleukemia (M6a) / Adult Pure Erythroid Leukemia (M6b) / Recurrent Adult Acute Myeloid Leukemia1
2CompletedTreatmentAdult Nasal Type Extranodal NK/T-Cell Lymphoma / Anaplastic Large Cell Lymphoma / Angioimmunoblastic T-Cell Lymphoma / Cutaneous B-Cell Non-Hodgkin Lymphoma / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Hepatosplenic T-Cell Lymphoma / Intraocular Lymphoma / Nodal marginal zone B-cell lymphomas / Noncutaneous Extranodal Lymphoma / Peripheral T-Cell Lymphoma (PTCL) / Recurrent Adult Burkitt Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Recurrent Adult Hodgkin's Lymphoma / Recurrent Adult Immunoblastic Large Cell Lymphoma / Recurrent Adult Lymphoblastic Lymphoma / Recurrent Adult T-Cell Leukemia/Lymphoma / Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma / Recurrent Grade 1 Follicular Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Recurrent Mantle Cell Lymphoma / Recurrent Marginal Zone Lymphoma / Recurrent Mycosis Fungoides/Sezary Syndrome / Recurrent Small Lymphocytic Lymphoma / Small Intestine Lymphoma / Splenic Marginal Zone Lymphoma / Testicular Lymphoma / Waldenstrom's Macroglobulinemia (WM)1
2CompletedTreatmentAdvanced Endometrial Adenocarcinoma, Stage III A, B, C1
2CompletedTreatmentAdvanced or Metastatic Non-Small Cell Lung Cancer1
2CompletedTreatmentAdvanced/Metastatic Non-Small Cell Lung Cancer1
2CompletedTreatmentBRCA1 Mutation Carrier / BRCA2 Mutation Carrier / Cancer, Breast / Hereditary Breast/Ovarian Cancer (brca1, brca2)1
2CompletedTreatmentBladder Cancers2
2CompletedTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter1
2CompletedTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter / Urethral Cancer1
2CompletedTreatmentBladder Cancers / Urethral Cancer1
2CompletedTreatmentBladder Transitional Cell Carcinoma Stage IV1
2CompletedTreatmentBrain Stem Neoplasms, Primary / Neoplasms, Brain Stem1
2CompletedTreatmentBrain and Central Nervous System Tumors6
2CompletedTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Extragonadal Germ Cell Tumor / Teratoma / Testicular germ cell tumour1
2CompletedTreatmentBrain and Central Nervous System Tumors / Metastatic Cancers / Unspecified Adult Solid Tumor, Protocol Specific1
2CompletedTreatmentBrain and Central Nervous System Tumors / Neuroblastomas1
2CompletedTreatmentBreast Cancer, Metastatic1
2CompletedTreatmentBrenner Tumor / Fallopian Tube Cancer / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mixed Epithelial Carcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Undifferentiated Adenocarcinoma / Primary Peritoneal Cavity Cancer / Recurrent Ovarian Epithelial Cancer1
2CompletedTreatmentBrenner Tumor / Fallopian Tube Cancer / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Undifferentiated Adenocarcinoma / Stage III Ovarian Epithelial Cancer / Stage IV Ovarian Epithelial Cancer1
2CompletedTreatmentCancer of the Ovary Treated as 2nd Line Therapy / Cervical Cancers / Muellerian Mixed Tumours / Non-Epithelial Ovarian Tumours / Tumours of the Uterus1
2CompletedTreatmentCancer, Breast32
2CompletedTreatmentCancer, Breast / Cancer, Ovarian / Lung Cancers1
2CompletedTreatmentCancer, Breast / HER2 Positive1
2CompletedTreatmentCancer, Breast / Invasive Breast Carcinoma / Metastatic Breast Carcinoma1
2CompletedTreatmentCancer, Breast / Leukemias / Lymphoma NOS / Multiple Myeloma and Plasma Cell Neoplasm / Testicular germ cell tumour / Unspecified Adult Solid Tumor, Protocol Specific / Unspecified Childhood Solid Tumor, Protocol Specific1
2CompletedTreatmentCancer, Breast / Neoplasms Metastasis1
2CompletedTreatmentCancer, Breast / Non Small Cell Lung Cancer (NSCLC)1
2CompletedTreatmentCancer, Ovarian15
2CompletedTreatmentCancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor / Head and Neck Cancers / Kidney Cancer / Liver Cancer / Lymphoma NOS / Neuroblastomas / Retinoblastoma / Sarcomas / Testicular germ cell tumour1
2CompletedTreatmentCancer, Ovarian / Clear Cell Mullerian Tumor / Fallopian Tube Cancer / Papillary Serous Mullerian Tumor / Primary Peritoneal Cancer1
2CompletedTreatmentCancer, Ovarian / Colorectal Cancers / Gastric Cancers / Gastrointestinal Carcinoid Tumor / Gastrointestinal Stromal Tumors / Peritoneal Cavity Cancer / Small Intestine Cancer1
2CompletedTreatmentCancer, Ovarian / Extragonadal Germ Cell Tumor1
2CompletedTreatmentCancer, Ovarian / Extragonadal Germ Cell Tumor / Testicular germ cell tumour / Unspecified Adult Solid Tumor, Protocol Specific1
2CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Malignant Tumor of Peritoneum1
2CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer3
2CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cavity Cancer3
2CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer2
2CompletedTreatmentCancer, Ovarian / Fallopian Tube Neoplasms / Peritoneal Neoplasms2
2CompletedTreatmentCancer, Ovarian / Neoplasms, Ovarian2
2CompletedTreatmentCancer, Ovarian / Peritoneal Cavity Cancer1
2CompletedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
2CompletedTreatmentCancer, Ovarian / Sarcomas / Small Intestine Cancer1
2CompletedTreatmentCancers / Carcinoma, Urothelial / Myeloproliferative Disorders1
2CompletedTreatmentCancers / Cervix Diseases / Epithelial Ovarian Cancer / Neoplasms, Ovarian / Primary Peritoneal Carcinoma / Tumors / Uterine Diseases1
2CompletedTreatmentCancers / Tumors1
2CompletedTreatmentCarboplatin Adverse Reaction / Lung Cancers1
2CompletedTreatmentCarcinoma of Unknown Primary1
2CompletedTreatmentCarcinoma of Unknown Primary Origin1
2CompletedTreatmentCarcinoma of Unknown Primary / Lung Cancers1
2CompletedTreatmentCarcinoma of the Prostate9
2CompletedTreatmentCarcinoma, Small Cell1
2CompletedTreatmentCarcinoma, Squamous Cell of the Head and Neck1
2CompletedTreatmentCarcinomas / Non-Squamous Non-Small-Cell Lung Cancer1
2CompletedTreatmentCarcinosarcoma / Leiomyosarcomas / Mesenchymal Tumor1
2CompletedTreatmentCervical Cancers2
2CompletedTreatmentChildhood Renal Cell Carcinoma / Clear Cell Renal Cell Carcinoma / Clear Cell Sarcoma of the Kidney / Papillary Renal Cell Carcinoma / Rhabdoid Tumors of the Kidney (RTK) / Stage I Renal Cell Cancer / Stage I Renal Wilms Tumor / Stage II Renal Cell Cancer / Stage II Renal Wilms Tumor / Stage III Renal Cell Cancer / Stage III Renal Wilms Tumor / Stage IV Renal Cell Cancer / Stage IV Renal Wilms Tumor1
2CompletedTreatmentCholangiocarcinomas / Gallbladder Cancer1
2CompletedTreatmentCiliary Body and Choroid Melanoma, Medium/Large Size / Extraocular Extension Melanoma / Iris Melanoma / Metastatic Intraocular Melanoma / Recurrent Intraocular Melanoma1
2CompletedTreatmentCiliary Body and Choroid Melanoma, Medium/Large Size / Extraocular Extension Melanoma / Iris Melanoma / Recurrent Intraocular Melanoma / Recurrent Melanoma / Stage IV Melanoma1
2CompletedTreatmentDiffuse Large B-Cell Lymphoma (DLBCL)1
2CompletedTreatmentDrug/Agent Toxicity by Tissue/Organ / Lung Cancers1
2CompletedTreatmentDysphagia / Lung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
2CompletedTreatmentEndometrial Adenocarcinomas / Endometrial Adenosquamous Cell Carcinoma / Endometrial Clear Cell Carcinoma / Endometrial Papillary Serous Carcinoma / Stage I Endometrial Carcinoma / Stage II Endometrial Carcinoma / Stage III Endometrial Carcinoma / Stage IV Endometrial Carcinoma1
2CompletedTreatmentEndometrial Cancers4
2CompletedTreatmentEndometrial Carcinoma1
2CompletedTreatmentEpithelial Ovarian Cancer1
2CompletedTreatmentEsophageal Cancers4
2CompletedTreatmentEsophageal Cancers / Gastric Cancers2
2CompletedTreatmentEsophagus Cancer1
2CompletedTreatmentEstrogen Receptor Negative / HER2/Neu Negative / Male Breast Carcinoma / Progesterone Receptor Negative / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Triple-Negative Breast Carcinoma1
2CompletedTreatmentEwings Sarcoma / Neuroblastomas / Non-rhabdomyosarcoma Soft Tissue Sarcomas1
2CompletedTreatmentExtensive Stage Small Cell Lung Cancer / Recurrent Small Cell Lung Cancer1
2CompletedTreatmentExtensive-Stage Small Cell Lung Cancer1
2CompletedTreatmentExtragonadal Germ Cell Tumor / Teratoma / Testicular germ cell tumour1
2CompletedTreatmentFallopian Tube Neoplasms / Neoplasms, Ovarian / Peritoneal Neoplasms1
2CompletedTreatmentGerm Cell Tumors / Testicular Neoplasms1
2CompletedTreatmentHER2-positive Breast Cancer / Male Breast Cancer / Recurrent Breast Cancer / Stage IV Breast Cancer1
2CompletedTreatmentHead and Neck Cancers10
2CompletedTreatmentHormone-Refractory Prostate Cancer1
2CompletedTreatmentInflammatory carcinoma of the breast / Locally Advanced Breast Cancer (LABC)1
2CompletedTreatmentKidney Cancer1
2CompletedTreatmentLeukemias1
2CompletedTreatmentLeukemias / Myelodysplastic Syndromes / Myelodysplastic/Myeloproliferative Diseases1
2CompletedTreatmentLiver Cancer1
2CompletedTreatmentLocally Advanced Non-Small Cell Lung Cancer / Non-Small-Cell Lung Carcinoma (NSCLC)1
2CompletedTreatmentLung Cancer, Small Cell1
2CompletedTreatmentLung Cancers43
2CompletedTreatmentLung Cancers / Neoplasms Metastasis / Non-Small-Cell Lung Carcinoma (NSCLC)1
2CompletedTreatmentLung Cancers / Non Small Cell Lung Cancer (NSCLC)1
2CompletedTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
2CompletedTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC) / Small Cell Lung Cancer (SCLC)1
2CompletedTreatmentLung Cancers / Small Cell Lung Carcinoma1
2CompletedTreatmentLymphoma NOS8
2CompletedTreatmentMalignant Gliomas1
2CompletedTreatmentMalignant Melanoma1
2CompletedTreatmentMalignant Pleural Effusions / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2CompletedTreatmentMalignant Pleural Mesothelioma (MPM)1
2CompletedTreatmentMelanoma2
2CompletedTreatmentMelanoma (Skin)2
2CompletedTreatmentMesothelioma2
2CompletedTreatmentMetastatic Breast Cancer (MBC)5
2CompletedTreatmentMetastatic Melanoma2
2CompletedTreatmentMetastatic Transitional Cell Cancer of the Renal Pelvis and Ureter / Recurrent Bladder Cancer / Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter / Squamous Cell Carcinoma of the Bladder / Stage IV Bladder Cancer / Transitional Cell Carcinoma of the Bladder1
2CompletedTreatmentMetastatic or Recurrent Squamous Cell Carcinoma of the Lung1
2CompletedTreatmentMixed Tumor, Mullerian1
2CompletedTreatmentNasopharyngeal Cancers1
2CompletedTreatmentNasopharyngeal Carcinoma2
2CompletedTreatmentNeoplasms1
2CompletedTreatmentNeoplasms, Breast1
2CompletedTreatmentNeoplasms, Head and Neck1
2CompletedTreatmentNeoplasms, Lung3
2CompletedTreatmentNeoplasms, Lung / Non-Small-Cell Lung Carcinoma (NSCLC) / Pulmonary Neoplasms1
2CompletedTreatmentNeoplasms, Ovarian2
2CompletedTreatmentNeuroblastomas8
2CompletedTreatmentNeuroblastomas / Tumor, Brain / Tumors, Central Nervous System1
2CompletedTreatmentNeuroendocrine Carcinomas1
2CompletedTreatmentNon Small Cell Lung Cancer (NSCLC)8
2CompletedTreatmentNon Small Cell Lung Carcinoma (NSCLC)2
2CompletedTreatmentNon-Hodgkin's Lymphoma (NHL)1
2CompletedTreatmentNon-Small -Cell Lung Cancer1
2CompletedTreatmentNon-Small Cell Lung Cancer Metastatic1
2CompletedTreatmentNon-Small Cell Lung Carcinoma (NSCLC)2
2CompletedTreatmentNon-Small-Cell Lung Cancer (NSCLC)3
2CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)32
2CompletedTreatmentNon-Small-Cell-Lung Cancer (NSCLC)1
2CompletedTreatmentNon-Squamous Non-Small Cell Lung Cancer3
2CompletedTreatmentOsteosarcomas1
2CompletedTreatmentOvarian Cancer Recurrent1
2CompletedTreatmentOvarian Carcinoma1
2CompletedTreatmentOvarian Carcinoma / Primary Peritoneal Carcinoma1
2CompletedTreatmentOvarian Clear Cell Cystadenocarcinoma / Stage III Ovarian Cancer / Stage IV Ovarian Cancer1
2CompletedTreatmentOvarian Epithelial Cancer Recurrent1
2CompletedTreatmentOvary Cancer1
2CompletedTreatmentPreviously Untreated Stage IV Non-Squamous Non Small Cell Lung Cancer1
2CompletedTreatmentPrimary Breast Cancer1
2CompletedTreatmentRecurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma2
2CompletedTreatmentRecurrent Melanoma / Stage IV Melanoma1
2CompletedTreatmentRecurrent Non-small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer4
2CompletedTreatmentRetinoblastoma3
2CompletedTreatmentSarcomas2
2CompletedTreatmentSmall Cell Lung Cancer (SCLC)1
2CompletedTreatmentSmall Cell Lung Carcinoma1
2CompletedTreatmentSoft Tissue Sarcoma (STS)2
2CompletedTreatmentSquamous Cell Carcinoma (SCC)1
2CompletedTreatmentSquamous Cell Carcinoma of the Head and Neck (SCCHN)1
2CompletedTreatmentStage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2CompletedTreatmentTesticular Neoplasms1
2CompletedTreatmentThymic Carcinoma / Thymoma1
2CompletedTreatmentTumors1
2CompletedTreatmentUnknown Primary Neoplasms1
2CompletedTreatmentUrologic Neoplasms1
2CompletedTreatmentUterine Cancers2
2CompletedTreatmentUterine Carcinosarcoma1
2Enrolling by InvitationTreatmentCancer, Ovarian1
2Not Yet RecruitingBasic ScienceRecurrent Non-Small Cell Lung Carcinoma / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2Not Yet RecruitingTreatmentBreast Cancer Female NOS / HER2 Positive Breast Cancers / Inflammatory carcinoma of the breast / Invasive Ductal Breast Cancer / Mucinous Breast Cancer Stage II / Tubular Breast Cancer Stage II / Tubular Breast Cancer Stage III1
2Not Yet RecruitingTreatmentCancer, Breast1
2Not Yet RecruitingTreatmentCancer, Ovarian / Ovarian Cancer Metastatic1
2Not Yet RecruitingTreatmentCarcinoma of the Prostate1
2Not Yet RecruitingTreatmentCarcinomas / Unknown Primary Neoplasms1
2Not Yet RecruitingTreatmentEndometrial Adenocarcinomas / Endometrial Cancers1
2Not Yet RecruitingTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Peritoneal Cancer1
2Not Yet RecruitingTreatmentEsophageal Cancers1
2Not Yet RecruitingTreatmentEstrogen Receptor Negative / HER2/Neu Negative / Invasive Breast Carcinoma / Progesterone Receptor Negative / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Carcinoma1
2Not Yet RecruitingTreatmentMetastatic Malignant Melanoma1
2Not Yet RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
2Not Yet RecruitingTreatmentSmall Cell Lung Cancer (SCLC)2
2Not Yet RecruitingTreatmentSmall Cell Lung Carcinoma1
2Not Yet RecruitingTreatmentT-Cell Lymphomas1
2RecruitingNot AvailableSeminoma1
2RecruitingBasic ScienceStage II Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer1
2RecruitingDiagnosticSquamous Cell Carcinoma of Oropharynx1
2RecruitingSupportive CareChemotherapeutic Agent Toxicity / Lethargy / Lung Cancers / Musculoskeletal Complications1
2RecruitingSupportive CareGliomas1
2RecruitingSupportive CareNausea / Vomiting1
2RecruitingTreatmentAcute Myeloid Leukaemias (AML) / Chronic Myelomonocytic Leukemia / Myelodysplastic Syndrome1
2RecruitingTreatmentAdenocarcinoma of the Esophagus / Adenocarcinoma of the Gastric Cardia / Adenocarcinomas of the Gastroesophageal Junction / Stage IIIA Esophageal Cancer / Stage IIIB Esophageal Cancer / Stage IIIC Esophageal Cancer1
2RecruitingTreatmentAdenocarcinoma of the Lung / Adenosquamous Lung Carcinoma / Bronchioloalveolar Carcinoma / Large Cell Lung Carcinoma / Non-Small Cell Lung Carcinoma (NSCLC) / Recurrent Non-Small Cell Lung Carcinoma / Squamous Cell Lung Carcinoma / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
2RecruitingTreatmentAdenocarcinoma of the Lung / Non-Small-Cell Lung Carcinoma (NSCLC)1
2RecruitingTreatmentAdenocarcinomas of the Esophagogastric Junction1
2RecruitingTreatmentAdvanced Ovarian Cancer1
2RecruitingTreatmentAdvanced Triple Negative Breast Cancer (TNBC) With High TAMs1
2RecruitingTreatmentAnal Basaloid Carcinoma / Anal Canal Cloacogenic Carcinoma / Anal Squamous Cell Carcinoma / Metastatic Anal Canal Carcinoma / Recurrent Anal Canal Carcinoma / Stage IIIB Anal Canal Cancer / Stage IV Anal Canal Cancer1
2RecruitingTreatmentAnaplastic Ependymoma / Ependymomas1
2RecruitingTreatmentAtypical Teratoid Rhabdoid Tumors (ATRT) / Malignant Rhabdoid Tumors (MRT)1
2RecruitingTreatmentBladder Cancers / Carcinoma, Urothelial / Renal Pelvis Cancer / Ureter Cancer / Urethra Cancer1
2RecruitingTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter / Ureter Cancer / Urethral Cancer1
2RecruitingTreatmentBrain and Central Nervous System Tumors1
2RecruitingTreatmentBrain and Central Nervous System Tumors / Extragonadal Germ Cell Tumor / Testicular germ cell tumour1
2RecruitingTreatmentBrenner Tumor / Malignant Ascites / Malignant Pleural Effusions / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mixed Epithelial Carcinoma / Ovarian Serous Cystadenocarcinoma / Ovarian Undifferentiated Adenocarcinoma / Recurrent Fallopian Tube Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Ovarian Germ Cell Tumor / Recurrent Primary Peritoneal Cavity Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Epithelial Cancer / Stage IIIA Ovarian Germ Cell Tumor / Stage IIIA Primary Peritoneal Cavity Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Epithelial Cancer / Stage IIIB Ovarian Germ Cell Tumor / Stage IIIB Primary Peritoneal Cavity Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Epithelial Cancer / Stage IIIC Ovarian Germ Cell Tumor / Stage IIIC Primary Peritoneal Cavity Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Epithelial Cancer / Stage IV Ovarian Germ Cell Tumor / Stage IV Primary Peritoneal Cavity Cancer1
2RecruitingTreatmentBurkitt's Lymphoma / CD20+ Lymphoblastic Lymphoma / Diffuse Large B-Cell Lymphoma (DLBCL) / Follicular Lymphoma, Grade III / Non-Hodgkin's Lymphoma (NHL) / Primary Mediastinal B-Cell Lymphoma1
2RecruitingTreatmentCancer, Breast8
2RecruitingTreatmentCancer, Breast / Neoadjuvant Chemotherapy1
2RecruitingTreatmentCancer, Breast / Neoplasms, Breast / Triple-Negative Breast Cancer (TNBC) / Triple-Negative Breast Neoplasms1
2RecruitingTreatmentCancer, Ovarian4
2RecruitingTreatmentCancer, Ovarian / Childhood Germ Cell Tumor / Teratoma1
2RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer1
2RecruitingTreatmentCancer, Ovarian / Fallopian Tube Carcinoma / Peritoneal Carcinoma1
2RecruitingTreatmentCancers1
2RecruitingTreatmentCancers of the Head and Neck / Head and Neck Cancers / Head and Neck Squamous Cell Carcinoma (HNSCC)1
2RecruitingTreatmentCarcinoma, Breast1
2RecruitingTreatmentCarcinoma, Non-squamous Non-small-cell Lung1
2RecruitingTreatmentCervical Cancer, Cancer, Metastatic Cancers1
2RecruitingTreatmentCervical Cancers1
2RecruitingTreatmentChildhood Central Nervous System Germ Cell Tumor / Childhood Central Nervous System Germinoma1
2RecruitingTreatmentDuctal Carcinoma In Situ1
2RecruitingTreatmentEGFR Activating Mutation / Non-Small Cell Lung Cancer Metastatic1
2RecruitingTreatmentEndometrial Adenocarcinomas / Stage IA Uterine Corpus Cancer / Stage IB Uterine Corpus Cancer / Stage II Uterine Corpus Cancer / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
2RecruitingTreatmentEndometrial Cancers3
2RecruitingTreatmentEndometrial Serous Adenocarcinoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC1 Uterine Corpus Cancer / Stage IIIC2 Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
2RecruitingTreatmentEpithelial Ovarian Cancer1
2RecruitingTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Fallopian Tube Carcinoma / Ovarian Carcinoma / Primary Peritoneal Carcinoma / Stage III Ovarian Cancer / Stage IV Ovarian Cancer1
2RecruitingTreatmentEpithelial Ovarian Carcinoma1
2RecruitingTreatmentEstrogen Receptor Negative / HER2/Neu Negative / Inflammatory carcinoma of the breast / Progesterone Receptor Negative / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Cancer (TNBC)1
2RecruitingTreatmentEstrogen Receptor-negative Breast Cancer / HER2-Negative Breast Cancer / Progesterone Receptor-negative Breast Cancer / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Cancer (TNBC)1
2RecruitingTreatmentFallopian Tube Carcinoma / Ovarian Carcinoma / Peritoneal Carcinoma1
2RecruitingTreatmentFollicular Lymphoma, Grade 3b / Lymphoma, B-Cell / Lymphoma, Follicular, Grade 3b / Lymphoma, Large B-Cell, Diffuse1
2RecruitingTreatmentGastric (Stomach) Cancer / Gastrointestinal Stromal Tumors (GISTs) / Neoplasm of Cardioesophageal Junction / Stomach Cancer1
2RecruitingTreatmentGastrointestinal Neuroendocrine Carcinomas1
2RecruitingTreatmentHead and Neck Cancers2
2RecruitingTreatmentHead and Neck Cancers / Squamous Cell Carcinoma of the Head and Neck (SCCHN)2
2RecruitingTreatmentHigh Grade Ovarian Serous Adenocarcinoma / Ovarian Endometrioid Tumor / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer1
2RecruitingTreatmentHuman Papilloma Virus Infection / Stage III Squamous Cell Carcinoma of the Hypopharynx / Stage III Squamous Cell Carcinoma of the Larynx / Stage III Squamous Cell Carcinoma of the Oropharynx / Stage III Verrucous Carcinoma of the Larynx / Stage IV Squamous Cell Carcinoma of the Hypopharynx / Stage IV Verrucous Carcinoma of the Larynx / Stage IVA Squamous Cell Carcinoma of the Larynx / Stage IVA Squamous Cell Carcinoma of the Oropharynx / Stage IVA Verrucous Carcinoma of the Larynx / Stage IVB Squamous Cell Carcinoma of the Larynx / Stage IVB Squamous Cell Carcinoma of the Oropharynx / Stage IVB Verrucous Carcinoma of the Larynx / Stage IVC Squamous Cell Carcinoma of the Larynx / Stage IVC Squamous Cell Carcinoma of the Oropharynx / Stage IVC Verrucous Carcinoma of the Larynx1
2RecruitingTreatmentHuman Papilloma Virus Infection / Stage III Squamous Cell Carcinoma of the Oropharynx / Stage IVA Squamous Cell Carcinoma of the Oropharynx / Stage IVB Squamous Cell Carcinoma of the Oropharynx2
2RecruitingTreatmentLaryngeal Cancer1
2RecruitingTreatmentLocalized Urothelial Carcinoma of the Renal Pelvis and Ureter / Recurrent Urothelial Carcinoma of the Renal Pelvis and Ureter / Regional Urothelial Carcinoma of the Renal Pelvis and Ureter1
2RecruitingTreatmentLocally Advanced Non-Small Cell Lung Cancer1
2RecruitingTreatmentLung Cancers7
2RecruitingTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
2RecruitingTreatmentLymphoma NOS1
2RecruitingTreatmentMedulloblastomas / Neuroectodermal Tumors, Primitive / Tumor, Brain1
2RecruitingTreatmentMelanoma1
2RecruitingTreatmentMetastatic Breast Cancer (MBC)1
2RecruitingTreatmentMetastatic, Cerebral Primitive Neuroectodermal Tumors1
2RecruitingTreatmentNasopharyngeal Neoplasms1
2RecruitingTreatmentNeoplasms, Breast2
2RecruitingTreatmentNeoplasms, Esophageal / Stomach Neoplasms1
2RecruitingTreatmentNeoplasms, Head and Neck1
2RecruitingTreatmentNeoplasms, Lung1
2RecruitingTreatmentNeoplasms / Neoplasms, Advanced Solid / Recurrent Solid Neoplasm1
2RecruitingTreatmentNeuroblastomas1
2RecruitingTreatmentNon Small Cell Lung Cancer (NSCLC)3
2RecruitingTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
2RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)13
2RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC) / Squamous Cell Carcinoma (SCC)1
2RecruitingTreatmentOesophageal Cancer1
2RecruitingTreatmentOvarian Epithelial Cancer Recurrent1
2RecruitingTreatmentOvarian Granulosa Cell Tumor / Ovarian Gynandroblastoma / Ovarian Sertoli-Leydig Cell Tumors / Ovarian Sex Cord Tumor With Annular Tubules / Ovarian Sex Cord-Stromal Tumor / Ovarian Sex Cord-Stromal Tumor of Mixed or Unclassified Cell Types / Ovarian Steroid Cell Tumor1
2RecruitingTreatmentOvarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation1
2RecruitingTreatmentPediatric Solid Tumors1
2RecruitingTreatmentProstatic Neoplasms1
2RecruitingTreatmentRefractory Pediatric AML / Refractory Pediatric Solid Tumors / Relapsed Pediatric AML / Relapsed Pediatric Solid Tumors1
2RecruitingTreatmentResidual Tumor / Triple-Negative Invasive Breast Carcinoma1
2RecruitingTreatmentRetinoblastoma1
2RecruitingTreatmentSalivary Gland Cancers1
2RecruitingTreatmentSeminoma1
2RecruitingTreatmentSmall Cell Lung Cancer (SCLC)1
2RecruitingTreatmentSquamous Cell Carcinoma of the Anus1
2RecruitingTreatmentSquamous Cell Carcinoma of the Head and Neck (SCCHN)1
2RecruitingTreatmentSquamous Cell Lung Cancer1
2RecruitingTreatmentStage II Lymphoepithelioma of the Nasopharynx / Stage II Squamous Cell Carcinoma of the Nasopharynx / Stage III Lymphoepithelioma of the Nasopharynx / Stage III Squamous Cell Carcinoma of the Nasopharynx / Stage IV Lymphoepithelioma of the Nasopharynx / Stage IV Squamous Cell Carcinoma of the Nasopharynx1
2RecruitingTreatmentStage III Non-Small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
2RecruitingTreatmentStage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
2RecruitingTreatmentTesticular Cancer1
2RecruitingTreatmentTriple Negative Breast Neoplasms1
2RecruitingTreatmentTriple-Negative Breast Cancer (TNBC)1
2RecruitingTreatmentTumor, Brain1
2RecruitingTreatmentUnknown Primary Tumors1
2RecruitingTreatmentUntreated Childhood Medulloblastoma1
2SuspendedTreatmentEstrogen Receptor-negative Breast Cancer / HER2-Negative Breast Cancer / Progesterone Receptor-negative Breast Cancer / Stage II Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Cancer (TNBC)1
2TerminatedNot AvailableCarcinoma of Unknown Primary1
2TerminatedTreatmentAdenocarcinoma of the Distal Esophagus / Adenocarcinoma of the Proximal Stomach / Adenocarcinomas of the Gastroesophageal Junction / Gastroesophageal Adenocarcinoma1
2TerminatedTreatmentAdvanced Non-Small Cell Lung Cancer1
2TerminatedTreatmentB-cell Childhood Acute Lymphoblastic Leukemia / Childhood Burkitt Lymphoma / Childhood Diffuse Large Cell Lymphoma / Childhood Immunoblastic Large Cell Lymphoma / L3 Childhood Acute Lymphoblastic Leukemia / Recurrent Childhood Acute Lymphoblastic Leukemia / Recurrent Childhood Large Cell Lymphoma / Recurrent Childhood Lymphoblastic Lymphoma / Recurrent Childhood Small Noncleaved Cell Lymphoma1
2TerminatedTreatmentBile Duct Cancer / Cancer of Gallbladder / Cholangiocarcinomas / Hepatobiliary Neoplasms / Liver Cancer1
2TerminatedTreatmentBladder Cancers1
2TerminatedTreatmentBrain and Central Nervous System Tumors / Drug/Agent Toxicity by Tissue/Organ / Lymphoma NOS / Thrombocytopenias1
2TerminatedTreatmentCancer, Breast4
2TerminatedTreatmentCancer, Breast / Recurrent Breast Cancer / Stage IV Breast Cancer1
2TerminatedTreatmentCancer, Ovarian4
2TerminatedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Mixed Tumor, Mesodermal / Primary Peritoneal Carcinoma1
2TerminatedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer / Stage 3 Cancer / Stage 4 Cancer1
2TerminatedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cavity Cancer2
2TerminatedTreatmentCarcinoma of the Prostate1
2TerminatedTreatmentDrug/Agent Toxicity by Tissue/Organ / Head and Neck Cancers / Oral Complications / Radiation Toxicity1
2TerminatedTreatmentEndometrial Cancers1
2TerminatedTreatmentEpendymomas1
2TerminatedTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Primary Peritoneal Cancer1
2TerminatedTreatmentEsophageal Cancers1
2TerminatedTreatmentHead and Neck Cancers1
2TerminatedTreatmentLung Cancers9
2TerminatedTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
2TerminatedTreatmentLymphoma, Large B-Cell, Diffuse / Non-Hodgkin's Lymphoma (NHL)1
2TerminatedTreatmentMalignant Ovarian Mixed Epithelial Tumor / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Primary Peritoneal Carcinoma / Stage III Ovarian Cancer / Undifferentiated Ovarian Carcinoma1
2TerminatedTreatmentMelanoma2
2TerminatedTreatmentMelanoma (Skin)1
2TerminatedTreatmentMetastatic Breast Cancer (MBC)2
2TerminatedTreatmentNeoplasms, Esophageal1
2TerminatedTreatmentNeoplasms, Lung1
2TerminatedTreatmentNeoplasms, Oropharyngeal1
2TerminatedTreatmentNeoplasms, Ovarian1
2TerminatedTreatmentNon Small Cell Lung Cancer (NSCLC)2
2TerminatedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)8
2TerminatedTreatmentPatients With Advanced Ovarian Cancer Sensitive to Platinum-based Chemotherapy1
2TerminatedTreatmentRecurrent Non-small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2TerminatedTreatmentSmall Cell Lung Cancer (SCLC)2
2TerminatedTreatmentStage IB Esophageal Adenocarcinoma / Stage IIA Esophageal Adenocarcinoma / Stage IIB Esophageal Adenocarcinoma / Stage IIIA Esophageal Adenocarcinoma / Stage IIIB Esophageal Adenocarcinoma / Stage IIIC Esophageal Adenocarcinoma1
2TerminatedTreatmentUterine Neoplasms1
2WithdrawnNot AvailableNeoplasms, Lung / Non-Small-Cell Lung Carcinoma (NSCLC)1
2WithdrawnTreatmentBrain and Central Nervous System Tumors1
2WithdrawnTreatmentBrain and Central Nervous System Tumors / Neuroblastomas / Retinoblastoma / Sarcomas1
2WithdrawnTreatmentCancer of Head and Neck1
2WithdrawnTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cavity Cancer1
2WithdrawnTreatmentCervical Cancers1
2WithdrawnTreatmentHuman Papilloma Virus (HPV) / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1
2WithdrawnTreatmentLung Cancers3
2WithdrawnTreatmentNon-small Cell Lung Cancer, Stage III1
2WithdrawnTreatmentRecurrent Non-small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2, 3Active Not RecruitingTreatmentCancer of the Breast / Cancer, Breast / Estrogen Receptor- Negative Breast Cancer / HER2- Negative Breast Cancer / Metastatic Breast Cancer (MBC) / Progesterone Receptor- Negative Breast Cancer / Recurrent Breast Cancer / Stage IV Breast Cancer / Triple-Negative Breast Cancer (TNBC) / Triple-negative Metastatic Breast Cancer / Tumors, Breast1
2, 3Active Not RecruitingTreatmentChronic Myeloproliferative Disorders / Leukemias / Lymphoma NOS / Myelodysplastic Syndromes / Myelodysplastic/Myeloproliferative Diseases / Nonmalignant Neoplasm / Unspecified Adult Solid Tumor, Protocol Specific / Unspecified Childhood Solid Tumor, Protocol Specific1
2, 3Active Not RecruitingTreatmentEpendymomas / Medulloblastomas / Recurrent Brain Tumors / Supratentorial PNETs1
2, 3Active Not RecruitingTreatmentHead and Neck Cancers1
2, 3Active Not RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
2, 3CompletedTreatmentAdenocarcinoma of the Lung / Bronchoalveolar Cell Lung Cancer / Large Cell Lung Cancer / Recurrent Non-small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
2, 3CompletedTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter / Urethral Cancer1
2, 3CompletedTreatmentBreast Cancer Female NOS / HER-2 Positive Breast Cancer / Inflammatory Breast Cancer Stage IV / Inflammatory carcinoma of the breast / Invasive Ductal Breast Cancer / Mucinous Breast Cancer Stage II / Tubular Breast Cancer Stage II / Tubular Breast Cancer Stage III1
2, 3CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
2, 3CompletedTreatmentLung Cancers2
2, 3CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
2, 3RecruitingTreatmentCancer, Breast1
2, 3RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer1
2, 3RecruitingTreatmentChildhood Ependymoma1
2, 3RecruitingTreatmentFIGO Stages II to IV / Primary Malignant Neoplasm of Ovary1
2, 3RecruitingTreatmentUrothelial Advanced or Metastatic Cancer1
2, 3SuspendedTreatmentEndometrial Adenocarcinomas / Endometrial Clear Cell Adenocarcinoma / Endometrial Serous Adenocarcinoma / Endometrial Undifferentiated Carcinoma / Recurrent Uterine Corpus Carcinoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
2, 3TerminatedTreatmentAnaplastic Thyroid Cancers1
2, 3TerminatedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer1
2, 3TerminatedTreatmentNeuroblastomas1
2, 3TerminatedTreatmentStage IIIB or IV Non-Small Cell Lung Cancer1
3Active Not RecruitingNot AvailableBrain and Central Nervous System Tumors / Cognitive/Functional Effects / Long-Term Effects Secondary to Cancer Therapy in Children / Ototoxicity1
3Active Not RecruitingSupportive CareUnspecified Adult Solid Tumor, Protocol Specific1
3Active Not RecruitingTreatmentAdenocarcinomas of the Gastroesophageal Junction / Esophageal Adenocarcinomas / Stage IB Esophageal Cancer / Stage IIA Esophageal Cancer / Stage IIB Esophageal Cancer / Stage IIIA Esophageal Cancer / Stage IIIB Esophageal Cancer1
3Active Not RecruitingTreatmentAdult Renal Wilms Tumor / Beckwith-Wiedemann Syndrome / Childhood Renal Wilms Tumor / Diffuse Hyperplastic Perilobar Nephroblastomatosis / Hemihypertrophy / Stage I Renal Wilms Tumor / Stage II Renal Wilms Tumor / Stage III Renal Wilms Tumor / Stage IV Renal Wilms Tumor / Stage V Renal Wilms Tumor1
3Active Not RecruitingTreatmentAdvanced Non-Small Cell Lung Cancer1
3Active Not RecruitingTreatmentBMI >30 kg/m2 / Endometrial Clear Cell Adenocarcinoma / Endometrial Serous Adenocarcinoma / Lethargy / Neurotoxicity Syndrome / Stage I Uterine Corpus Cancer / Stage II Uterine Corpus Cancer1
3Active Not RecruitingTreatmentBorderline Ovarian Mucinous Tumor / Ovarian Mucinous Cystadenocarcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Stage IA Fallopian Tube Cancer / Stage IA Ovarian Cancer / Stage IB Fallopian Tube Cancer / Stage IB Ovarian Cancer / Stage IC Fallopian Tube Cancer / Stage IC Ovarian Cancer / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer1
3Active Not RecruitingTreatmentBrain and Central Nervous System Tumors2
3Active Not RecruitingTreatmentBreast Cancer Stage I1
3Active Not RecruitingTreatmentCancer, Breast3
3Active Not RecruitingTreatmentCancer, Ovarian4
3Active Not RecruitingTreatmentCancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor1
3Active Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer1
3Active Not RecruitingTreatmentCarcinoma of Unknown Primary1
3Active Not RecruitingTreatmentChildhood Atypical Teratoid/Rhabdoid Tumor1
3Active Not RecruitingTreatmentChoroid Plexus Tumors1
3Active Not RecruitingTreatmentColorectal Cancers1
3Active Not RecruitingTreatmentEndometrial Cancers2
3Active Not RecruitingTreatmentEndometrial Clear Cell Adenocarcinoma / Endometrial Serous Adenocarcinoma / Stage IA Uterine Corpus Cancer / Stage IB Uterine Corpus Cancer / Stage II Uterine Corpus Cancer / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer1
3Active Not RecruitingTreatmentEpithelial Ovarian Cancer / Fallopian Tube Cancer / Primary Peritoneal Cancer1
3Active Not RecruitingTreatmentEstrogen Receptor Positive / HER2/Neu Positive / Progesterone Receptor Positive / Stage IB Breast Cancer / Stage II Breast Cancer / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer1
3Active Not RecruitingTreatmentExtensive-Stage Small Cell Lung Cancer1
3Active Not RecruitingTreatmentExtragonadal Germ Cell Tumor / Testicular germ cell tumour1
3Active Not RecruitingTreatmentExtraocular Retinoblastoma1
3Active Not RecruitingTreatmentFallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Mucinous Adenocarcinoma / Fallopian Tube Transitional Cell Carcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Adenocarcinofibroma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Adenocarcinoma / Ovarian Serous Adenocarcinoma / Ovarian Transitional Cell Carcinoma / Primary Peritoneal Serous Adenocarcinoma / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer / Undifferentiated Ovarian Carcinoma1
3Active Not RecruitingTreatmentFallopian Tube Neoplasms / Genital Diseases, Female / Neoplasms, Ovarian / Ovarian Diseases / Peritoneal Neoplasms1
3Active Not RecruitingTreatmentHER2/Neu Positive / Male Breast Carcinoma / Recurrent Breast Carcinoma / Stage IV Breast Cancer1
3Active Not RecruitingTreatmentIntraocular Retinoblastoma1
3Active Not RecruitingTreatmentLocalized Resectable Neuroblastoma / Localized Unresectable Neuroblastoma / Recurrent Neuroblastoma / Regional Neuroblastoma / Stage 4 Neuroblastoma / Stage 4S Neuroblastoma1
3Active Not RecruitingTreatmentLung Cancer - Non Small Cell1
3Active Not RecruitingTreatmentLung Cancers9
3Active Not RecruitingTreatmentLung Cancers / Radiation Toxicity1
3Active Not RecruitingTreatmentMalignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Undifferentiated Ovarian Carcinoma1
3Active Not RecruitingTreatmentNSCLC (Non-Small Cell Lung Cancer)1
3Active Not RecruitingTreatmentNeoplasms, Ovarian / Peritoneal Neoplasms1
3Active Not RecruitingTreatmentNeuroblastomas5
3Active Not RecruitingTreatmentNon-Small Cell Lung Carcinoma (NSCLC) / Non-Small-Cell Lung Carcinoma (NSCLC)1
3Active Not RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)3
3Active Not RecruitingTreatmentNon-Squamous Non-Small Cell Lung Cancer1
3Active Not RecruitingTreatmentOvarian Carcinosarcoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Recurrent Uterine Corpus Sarcoma / Stage I Ovarian Cancer / Stage IA Fallopian Tube Cancer / Stage IA Ovarian Cancer / Stage IA Uterine Sarcoma / Stage IB Fallopian Tube Cancer / Stage IB Ovarian Cancer / Stage IB Uterine Sarcoma / Stage IC Fallopian Tube Cancer / Stage IC Ovarian Cancer / Stage IC Uterine Sarcoma / Stage II Ovarian Cancer / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIA Uterine Sarcoma / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIB Uterine Sarcoma / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIA Uterine Sarcoma / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIB Uterine Sarcoma / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IIIC Uterine Sarcoma / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer / Stage IVA Uterine Sarcoma / Stage IVB Uterine Sarcoma / Uterine Carcinosarcoma1
3Active Not RecruitingTreatmentRecurrent Hypopharyngeal Squamous Cell Carcinoma / Recurrent Laryngeal Squamous Cell Carcinoma / Recurrent Laryngeal Verrucous Carcinoma / Recurrent Lip and Oral Cavity Squamous Cell Carcinoma / Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary / Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Recurrent Oral Cavity Verrucous Carcinoma / Recurrent Oropharyngeal Squamous Cell Carcinoma / Recurrent Salivary Gland Carcinoma / Salivary Gland Squamous Cell Carcinoma / Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary / Stage IV Hypopharyngeal Squamous Cell Carcinoma / Stage IV Major Salivary Gland Carcinoma / Stage IVA Laryngeal Squamous Cell Carcinoma / Stage IVA Laryngeal Verrucous Carcinoma / Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma / Stage IVA Major Salivary Gland Carcinoma / Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Stage IVA Oral Cavity Verrucous Carcinoma / Stage IVA Oropharyngeal Squamous Cell Carcinoma / Stage IVB Laryngeal Squamous Cell Carcinoma / Stage IVB Laryngeal Verrucous Carcinoma / Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma / Stage IVB Major Salivary Gland Carcinoma / Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Stage IVB Oral Cavity Verrucous Carcinoma / Stage IVB Oropharyngeal Squamous Cell Carcinoma / Stage IVC Laryngeal Squamous Cell Carcinoma / Stage IVC Laryngeal Verrucous Carcinoma / Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma / Stage IVC Major Salivary Gland Carcinoma / Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma / Stage IVC Oral Cavity Verrucous Carcinoma / Stage IVC Oropharyngeal Squamous Cell Carcinoma / Tongue Carcinoma / Untreated Metastatic Squamous Cell Carcinoma to Neck With Occult Primary1
3Active Not RecruitingTreatmentRecurrent Large Cell Lung Carcinoma / Recurrent Lung Adenocarcinoma / Recurrent Squamous Cell Lung Carcinoma / Stage IV Large Cell Lung Carcinoma / Stage IV Lung Adenocarcinoma / Stage IV Squamous Cell Lung Carcinoma1
3Active Not RecruitingTreatmentRecurrent Platinum-sensitive Ovarian Cancer1
3Active Not RecruitingTreatmentRetinal Neoplasms / Retinoblastoma1
3Active Not RecruitingTreatmentSmall Cell Lung Carcinoma1
3Active Not RecruitingTreatmentSquamous Cell Head and Neck Carcinoma1
3Active Not RecruitingTreatmentStage IV or Recurrent Non-Small Cell Lung Cancer1
3Active Not RecruitingTreatmentTriple Negative Breast Cancer (TNBC)1
3Active Not RecruitingTreatmentTumor, Brain / Tumors, Central Nervous System1
3Active Not RecruitingTreatmentTumors, Solid1
3Active Not RecruitingTreatmentUnresectable or Metastatic Melanoma1
3Active Not RecruitingTreatmentUntreated Childhood Medulloblastoma / Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor1
3CompletedPreventionNon Small Cell Lung Carcinoma (NSCLC)1
3CompletedSupportive CareChemotherapeutic Agent Toxicity / Neuropathy / Neurotoxicity Syndrome / Pain / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer1
3CompletedSupportive CareDrug/Agent Toxicity by Tissue/Organ / Lung Cancers / Oral Complications / Radiation Toxicity1
3CompletedTreatmentAdenocarcinoma of the Lung / Adenosquamous Cell Lung Cancer / Bronchoalveolar Cell Lung Cancer / Large Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IB Non-small Cell Lung Cancer1
3CompletedTreatmentAdenocarcinoma of the Lung / Adenosquamous Cell Lung Cancer / Large Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
3CompletedTreatmentAdvanced Non-Small Cell Lung Cancer1
3CompletedTreatmentBladder Cancers / Transitional Cell Cancer of the Renal Pelvis and Ureter / Urethral Cancer1
3CompletedTreatmentBladder Cancers / Urethral Cancer1
3CompletedTreatmentBrain and Central Nervous System Tumors2
3CompletedTreatmentCancer, Breast4
3CompletedTreatmentCancer, Ovarian6
3CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer3
3CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cavity Cancer1
3CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Neoplasms1
3CompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Primary Peritoneal Cavity Cancer4
3CompletedTreatmentCancer, Ovarian / Peritoneal Cavity Cancer1
3CompletedTreatmentCancer, Ovarian / Primary Peritoneal Cavity Cancer2
3CompletedTreatmentCarcinoma, Squamous Cell of the Head and Neck1
3CompletedTreatmentChildhood Germ Cell Tumor / Extragonadal Germ Cell Tumor / Testicular germ cell tumour1
3CompletedTreatmentChildhood Hepatoblastoma / Recurrent Childhood Liver Cancer / Stage I Childhood Liver Cancer1
3CompletedTreatmentChildhood Malignant Fibrous Histiocytoma of Bone / Sarcomas1
3CompletedTreatmentFallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Mucinous Adenocarcinoma / Fallopian Tube Serous Adenocarcinoma / Fallopian Tube Transitional Cell Carcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Adenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Adenocarcinoma / Ovarian Serous Adenocarcinoma / Ovarian Transitional Cell Carcinoma / Primary Peritoneal Serous Adenocarcinoma / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer / Undifferentiated Fallopian Tube Carcinoma / Undifferentiated Ovarian Carcinoma1
3CompletedTreatmentFallopian Tube Neoplasms / Genital Neoplasms, Female / Neoplasms, Ovarian / Pelvic Neoplasms / Peritoneal Neoplasms1
3CompletedTreatmentHead and Neck Cancers1
3CompletedTreatmentHypopharynx Cancer / Larynx Cancer / Oral Cancers / Oropharynx Cancers1
3CompletedTreatmentIntraocular Retinoblastoma2
3CompletedTreatmentKidney Cancer1
3CompletedTreatmentLiver Cancer1
3CompletedTreatmentLung Cancers16
3CompletedTreatmentMelanoma1
3CompletedTreatmentMucosal Melanoma / Recurrent Melanoma / Stage IIIA Skin Melanoma / Stage IIIB Skin Melanoma / Stage IIIC Skin Melanoma / Stage IV Skin Melanoma1
3CompletedTreatmentNeoplasms, Breast1
3CompletedTreatmentNeuroblastomas5
3CompletedTreatmentNon Small Cell Lung Cancer (NSCLC)2
3CompletedTreatmentNon Small Cell Lung Carcinoma (NSCLC)1
3CompletedTreatmentNon-Small Cell Lung Cancer Metastatic1
3CompletedTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
3CompletedTreatmentNon-Small-Cell Lung Cancer (NSCLC)1
3CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)13
3CompletedTreatmentNon-Squamous Non-Small Cell Lung Cancer1
3CompletedTreatmentPrimary Peritoneal Cavity Cancer / Stage III Ovarian Epithelial Cancer / Stage IV Ovarian Epithelial Cancer1
3CompletedTreatmentSkin Cancers1
3CompletedTreatmentSmall Cell Lung Cancer (SCLC)1
3CompletedTreatmentSquamous Cell Lung Cancer1
3CompletedTreatmentTesticular germ cell tumour1
3CompletedTreatmentTumor, Brain / Tumors, Central Nervous System2
3CompletedTreatmentUnknown Primary Neoplasms1
3Enrolling by InvitationTreatmentCancer, Ovarian / Neoplasms, Ovarian / Ovarian Germ Cell Cancer1
3Enrolling by InvitationTreatmentCancer, Ovarian / Neoplasms, Ovarian / Ovarian Sex Cord Stromal Tumor1
3Not Yet RecruitingTreatmentCancer, Breast1
3Not Yet RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Neoplasms1
3Not Yet RecruitingTreatmentCervical Cancers2
3Not Yet RecruitingTreatmentGestational Trophoblastic Neoplasms1
3Not Yet RecruitingTreatmentInvasive Ductal Breast Carcinoma1
3RecruitingDiagnosticCancer, Breast1
3RecruitingTreatment(FIGO Stage IIB-IVA) / Uterine Cervical Cancer1
3RecruitingTreatmentAdenocarcinoma of the Oesophago-gastric Junction / Adenocarcinoma of the Oesophagus / Junctional Tumours / Oesophageal Cancer / Oesophageal Tumours1
3RecruitingTreatmentAdenocarcinoma, Mucinous / Carcinoma, Undifferentiated / Clear Cell Adenocarcinoma / Fallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Endometrioid Adenocarcinoma / Fallopian Tube Mucinous Adenocarcinoma / Fallopian Tube Serous Adenocarcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Brenner Tumor / Ovarian Clear Cell Adenocarcinofibroma / Ovarian Endometrioid Adenocarcinoma / Ovarian Seromucinous Carcinoma / Ovarian Serous Adenocarcinoma / Primary Peritoneal Serous Adenocarcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Undifferentiated Fallopian Tube Carcinoma / Undifferentiated Ovarian Carcinoma1
3RecruitingTreatmentAdenocarcinomas of the Esophagogastric Junction / Esophageal Adenocarcinoma (UICC TNM7)1
3RecruitingTreatmentBladder Cancers / Urothelial Cancer1
3RecruitingTreatmentBreast Adenocarcinoma / Estrogen Receptor Negative / HER2/Neu Negative / Progesterone Receptor Negative / Stage IB Breast Cancer / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Carcinoma1
3RecruitingTreatmentBreast Cancer Female NOS / HER2 Positive Breast Cancers / Inflammatory carcinoma of the breast / Invasive Ductal Breast Cancer / Mucinous Breast Cancer Stage II / Tubular Breast Cancer Stage II / Tubular Breast Cancer Stage III1
3RecruitingTreatmentCancer, Breast3
3RecruitingTreatmentCancer, Ovarian3
3RecruitingTreatmentCancer, Ovarian / Neoplasms, Ovarian1
3RecruitingTreatmentCarcinoma, Squamous Cell of Head and Neck1
3RecruitingTreatmentCarcinoma, Urothelial1
3RecruitingTreatmentCervical Adenocarcinoma / Cervical Adenosquamous Carcinoma / Cervical Squamous Cell Carcinoma / Chemotherapeutic Agent Toxicity / Cognitive Side Effects of Cancer Therapy / Psychological Impact of Cancer / Radiation Toxicity / Sexual Dysfunction and Infertility / Stage IB Cervical Cancer / Stage IIA Cervical Cancer / Stage IIB Cervical Cancer / Stage III Cervical Cancer / Stage IVA Cervical Cancer1
3RecruitingTreatmentCervical Cancers3
3RecruitingTreatmentChildhood Infratentorial Ependymoma / Childhood Supratentorial Ependymoma / Newly Diagnosed Childhood Ependymoma1
3RecruitingTreatmentChildhood Teratoma / Choriocarcinoma / Extragonadal Seminoma / Germ Cell Tumors / Germinoma / Malignant Germ Cell Neoplasm / Mixed Germ Cell Tumor / Non-seminomatous Germ Cell Tumors / Seminoma / Teratoma / Yolk Sac Tumor1
3RecruitingTreatmentDeleterious BRCA1 Gene Mutation / Deleterious BRCA2 Gene Mutation / Endometrial Undifferentiated Carcinoma / Fallopian Tube Clear Cell Adenocarcinoma / Fallopian Tube Transitional Cell Carcinoma / Malignant Ovarian Mixed Epithelial Tumor / Ovarian Clear Cell Adenocarcinoma / Ovarian Endometrioid Tumor / Ovarian Seromucinous Carcinoma / Ovarian Serous Tumor / Ovarian Transitional Cell Carcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma / Undifferentiated Fallopian Tube Carcinoma / Undifferentiated Ovarian Carcinoma1
3RecruitingTreatmentEndometrial Cancers1
3RecruitingTreatmentEndometrial Clear Cell Adenocarcinoma / Endometrial Serous Adenocarcinoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer1
3RecruitingTreatmentEpithelial Ovarian Cancer1
3RecruitingTreatmentEsophageal Cancers1
3RecruitingTreatmentEstrogen Receptor Negative / HER2/Neu Negative / Invasive Breast Carcinoma / Progesterone Receptor Negative / Stage IIA Breast Cancer / Stage IIB Breast Cancer / Stage IIIA Breast Cancer / Stage IIIB Breast Cancer / Stage IIIC Breast Cancer / Triple-Negative Breast Carcinoma1
3RecruitingTreatmentFirst Line Non-Small Cell Lung Cancer1
3RecruitingTreatmentGanglioneuroblastoma / Localized Resectable Neuroblastoma / Localized Unresectable Neuroblastoma / Recurrent Neuroblastoma / Regional Neuroblastoma / Stage 4 Neuroblastoma1
3RecruitingTreatmentKidney Cancer1
3RecruitingTreatmentLocal Advanced Esophageal Squamous Cell Carcinoma1
3RecruitingTreatmentLow Grade Glioma (LGG)1
3RecruitingTreatmentLung Cancers3
3RecruitingTreatmentLung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
3RecruitingTreatmentMetastatic Breast Cancer (MBC)2
3RecruitingTreatmentMetastatic Head and Neck Cancer / Recurrent Head and Neck Cancer1
3RecruitingTreatmentMetastatic Non-Squamous Non-Small Cell Lung Cancer1
3RecruitingTreatmentNeoplasms, Endometrial1
3RecruitingTreatmentNeuroblastomas3
3RecruitingTreatmentNon Small Cell Lung Carcinoma (NSCLC)1
3RecruitingTreatmentNon-Hodgkin's Lymphoma (NHL)1
3RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)8
3RecruitingTreatmentNon-Squamous Non-Small Cell Lung Cancer4
3RecruitingTreatmentRecurrent Nasopharynx Carcinoma1
3RecruitingTreatmentRecurrent Ovarian Cancer1
3RecruitingTreatmentRetinoblastoma1
3RecruitingTreatmentSarcomas1
3RecruitingTreatmentSeminoma / Testicular Neoplasms1
3RecruitingTreatmentSmall Cell Lung Cancer (SCLC)1
3RecruitingTreatmentSquamous Cell Carcinoma of the Head and Neck (SCCHN)1
3RecruitingTreatmentSquamous Cell Carcinoma, Non-Small-Cell Lung1
3RecruitingTreatmentSquamous Non-Small Cell Lung Cancer1
3RecruitingTreatmentStage IIA Non-small Cell Lung Cancer / Stage IIB Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
3RecruitingTreatmentTransitional Cell Carcinoma of Ureter1
3SuspendedTreatmentBrain Cancer / Choroid Plexus Tumors1
3SuspendedTreatmentUntreated Childhood Medulloblastoma / Untreated Childhood Pineoblastoma / Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor1
3TerminatedNot AvailableStage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
3TerminatedTreatmentCancer, Breast2
3TerminatedTreatmentCancer, Ovarian2
3TerminatedTreatmentCarcinoma, Adenosquamous / Carcinoma, Large Cell / Non-Small-Cell Lung Carcinoma (NSCLC) / Squamous Cell Carcinoma (SCC)1
3TerminatedTreatmentExtensive Disease / First-Line / Small Cell Lung Cancer (SCLC)1
3TerminatedTreatmentLung Cancers1
3TerminatedTreatmentLymphoma NOS1
3TerminatedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)6
3WithdrawnTreatmentAnaplastic Thyroid Cancers1
3WithdrawnTreatmentExtensive-Stage Small Cell Lung Cancer1
3WithdrawnTreatmentLung Cancers2
4Active Not RecruitingTreatmentCancer, Ovarian1
4Active Not RecruitingTreatmentNeoplasms, Therapy-Associated1
4CompletedTreatmentCarcinoma, Large Cell / Neuroendocrine Tumors1
4CompletedTreatmentNon Small Cell Lung Cancer (NSCLC)1
4CompletedTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
4CompletedTreatmentRetinoblastoma1
4Not Yet RecruitingTreatmentCancers1
4RecruitingSupportive CarePlatinum Sensitive Ovarian Cancer / Recurrent Ovarian Cancer1
4RecruitingTreatmentAdenocarcinomas / Carcinoma, Large Cell / Carcinomas / Neoplasms, Lung / Non-Small-Cell Lung Carcinoma (NSCLC) / Squamous Cell Carcinoma (SCC)1
4RecruitingTreatmentCancer, Breast1
4RecruitingTreatmentIntracranial Germ Cell Tumors1
4RecruitingTreatmentMetastatic Breast Cancer (MBC)1
Not AvailableActive Not RecruitingNot AvailableCancer, Breast / Chemotherapeutic Agent Toxicity / Cognitive/Functional Effects / Lethargy / Long-Term Effects Secondary to Cancer Therapy in Adults / Neurotoxicity / Psychosocial Effects of Cancer and Its Treatment1
Not AvailableActive Not RecruitingNot AvailableStage I Ovarian Cancer / Stage IA Fallopian Tube Cancer / Stage IB Fallopian Tube Cancer / Stage IC Fallopian Tube Cancer / Stage II Ovarian Cancer / Stage IIA Fallopian Tube Cancer / Stage IIB Fallopian Tube Cancer / Stage IIC Fallopian Tube Cancer / Stage III Ovarian Cancer / Stage III Primary Peritoneal Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIC Fallopian Tube Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer1
Not AvailableActive Not RecruitingTreatmentAdult Acute Lymphoblastic Leukemia in Remission / Adult Acute Myeloid Leukemia in Remission / Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities / Adult Acute Myeloid Leukemia With Del(5q) / Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) / Adult Acute Myeloid Leukemia With T(15;17)(q22;q12) / Adult Acute Myeloid Leukemia With T(16;16)(p13;q22) / Adult Acute Myeloid Leukemia With T(8;21)(q22;q22) / Adult Nasal Type Extranodal NK/T-Cell Lymphoma / Childhood Acute Lymphoblastic Leukemia in Remission / Childhood Acute Myeloid Leukemia in Remission / Childhood Burkitt Lymphoma / Childhood Diffuse Large Cell Lymphoma / Childhood Immunoblastic Large Cell Lymphoma / Childhood Nasal Type Extranodal NK/T-cell Lymphoma / Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor (PNET) / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Hepatosplenic T-Cell Lymphoma / Intraocular Lymphoma / Nodal marginal zone B-cell lymphomas / Peripheral T-Cell Lymphoma (PTCL) / Plasma Cell Neoplasms / Primary Systemic Amyloidosis / Recurrent Adult Acute Lymphoblastic Leukemia / Recurrent Adult Acute Myeloid Leukemia / Recurrent Adult Burkitt Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Recurrent Adult Hodgkin's Lymphoma / Recurrent Adult Immunoblastic Large Cell Lymphoma / Recurrent Adult Lymphoblastic Lymphoma / Recurrent Childhood Acute Lymphoblastic Leukemia / Recurrent Childhood Acute Myeloid Leukemia / Recurrent Childhood Anaplastic Large Cell Lymphoma / Recurrent Childhood Grade III Lymphomatoid Granulomatosis / Recurrent Childhood Large Cell Lymphoma / Recurrent Childhood Lymphoblastic Lymphoma / Recurrent Childhood Small Noncleaved Cell Lymphoma / Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma / Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor / Recurrent Grade 1 Follicular Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Recurrent Malignant Testicular Germ Cell Tumor / Recurrent Mantle Cell Lymphoma / Recurrent Marginal Zone Lymphoma / Recurrent Neuroblastoma / Recurrent Small Lymphocytic Lymphoma / Recurrent/Refractory Childhood Hodgkin Lymphoma / Refractory Chronic Lymphocytic Leukemia / Refractory Multiple Myeloma / Regional Neuroblastoma / Splenic Marginal Zone Lymphoma / Testicular Lymphoma / Unspecified Adult Solid Tumor, Protocol Specific / Unspecified Childhood Solid Tumor, Protocol Specific / Waldenstrom's Macroglobulinemia (WM)1
Not AvailableActive Not RecruitingTreatmentAdvanced Non-Squamous Non-Small Cell Lung Cancer1
Not AvailableActive Not RecruitingTreatmentBrain and Central Nervous System Tumors / Cancer, Ovarian / Childhood Germ Cell Tumor / Extragonadal Germ Cell Tumor1
Not AvailableActive Not RecruitingTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Cancer1
Not AvailableActive Not RecruitingTreatmentEndometrial Adenocarcinomas / Endometrial Adenosquamous Carcinoma / Endometrial Clear Cell Adenocarcinoma / Endometrial Mucinous Adenocarcinoma / Endometrial Serous Adenocarcinoma / Endometrial Undifferentiated Carcinoma / Endometrioid Adenocarcinoma / Recurrent Uterine Corpus Carcinoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Uterine Corpus Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer / Uterine Carcinosarcoma1
Not AvailableActive Not RecruitingTreatmentHead and Neck Cancers1
Not AvailableActive Not RecruitingTreatmentIntraocular Retinoblastoma1
Not AvailableActive Not RecruitingTreatmentLymphoma NOS1
Not AvailableActive Not RecruitingTreatmentNeuroblastomas1
Not AvailableActive Not RecruitingTreatmentPrimary Central Nervous System Neoplasms1
Not AvailableActive Not RecruitingTreatmentRetinoblastoma1
Not AvailableActive Not RecruitingTreatmentUntreated Childhood Medulloblastoma / Untreated Childhood Pineoblastoma / Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor1
Not AvailableCompletedNot AvailableNeoplasms1
Not AvailableCompletedNot AvailableNeoplasms, Ovarian1
Not AvailableCompletedNot AvailableNonsquamous Nonsmall Cell Neoplasm of Lung1
Not AvailableCompletedTreatmentBrain and Central Nervous System Tumors1
Not AvailableCompletedTreatmentCancer, Ovarian / Fallopian Tube Cancer / Peritoneal Carcinoma1
Not AvailableCompletedTreatmentHypermethylation / Lung Cancers / Non Small Cell Lung Carcinoma (NSCLC)1
Not AvailableCompletedTreatmentLung Cancers1
Not AvailableCompletedTreatmentLymphoma, Large Cell / Non-Hodgkin's Lymphoma (NHL)1
Not AvailableCompletedTreatmentNeoplasms, Gynecologic1
Not AvailableCompletedTreatmentTumor, Brain / Tumors, Central Nervous System1
Not AvailableNot Yet RecruitingNot AvailableLung Cancers2
Not AvailableNot Yet RecruitingDiagnosticNon-Small-Cell Lung Carcinoma (NSCLC)1
Not AvailableNot Yet RecruitingTreatmentElderly Patients Diagnosed With Breast Cancer / HER-2 Positive Breast Cancer1
Not AvailableNot Yet RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
Not AvailableRecruitingNot AvailableUnspecified Childhood Solid Tumor, Protocol Specific1
Not AvailableRecruitingTreatmentAdenocarcinoma of the Lung / Adenosquamous Cell Lung Cancer / Large Cell Lung Cancer / Recurrent Non-small Cell Lung Cancer / Squamous Cell Lung Cancer / Stage IIA Non-small Cell Lung Cancer / Stage IIB Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer1
Not AvailableRecruitingTreatmentAdvanced Intra-Ocular Retinoblastoma / Retinoblastoma1
Not AvailableRecruitingTreatmentAtypical Teratoid/Rhabdoid Tumor (AT/RT) / CNS Tumors / Ewing's Family Tumors / Germ Cell Tumors / Hepatoblastomas / Medulloblastomas / Primary Malignant Brain Neoplasms / Renal Tumors / Retinoblastoma / Rhabdomyosarcomas / Soft Tissue Sarcoma (STS) / Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET)1
Not AvailableRecruitingTreatmentHormone-Resistant Prostate Cancer / Metastatic Prostate Carcinoma / Recurrent Prostate Carcinoma / Stage IV Prostate Cancer1
Not AvailableRecruitingTreatmentNeuroblastomas2
Not AvailableRecruitingTreatmentNon Small Cell Lung Cancer (NSCLC)1
Not AvailableRecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
Not AvailableRecruitingTreatmentRecurrent Fallopian Tube Cancer / Recurrent Ovarian Cancer / Recurrent Primary Peritoneal Cancer / Recurrent Uterine Corpus Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cavity Cancer / Stage IIIA Uterine Corpus Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cavity Cancer / Stage IIIB Uterine Corpus Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cavity Cancer / Stage IIIC Uterine Corpus Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cavity Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
Not AvailableRecruitingTreatmentRetinoblastoma2
Not AvailableRecruitingTreatmentStage IA Uterine Sarcoma / Stage IB Uterine Sarcoma / Stage IC Uterine Sarcoma / Stage IIA Uterine Sarcoma / Stage IIB Uterine Sarcoma / Stage IIIA Uterine Sarcoma / Stage IIIB Uterine Sarcoma / Stage IIIC Uterine Sarcoma / Stage IVA Uterine Sarcoma / Stage IVB Uterine Sarcoma / Uterine Carcinosarcoma1
Not AvailableSuspendedSupportive CareMalignant Ovarian Mixed Epithelial Tumor / Nausea and Vomiting / Ovarian Brenner Tumor / Ovarian Clear Cell Cystadenocarcinoma / Ovarian Endometrioid Adenocarcinoma / Ovarian Mucinous Cystadenocarcinoma / Ovarian Serous Cystadenocarcinoma / Stage II Ovarian Cancer / Stage IIA Fallopian Tube Cancer / Stage IIA Ovarian Cancer / Stage IIB Fallopian Tube Cancer / Stage IIB Ovarian Cancer / Stage IIC Fallopian Tube Cancer / Stage IIC Ovarian Cancer / Stage IIIA Fallopian Tube Cancer / Stage IIIA Ovarian Cancer / Stage IIIA Primary Peritoneal Cancer / Stage IIIB Fallopian Tube Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Primary Peritoneal Cancer / Stage IIIC Fallopian Tube Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Primary Peritoneal Cancer / Stage IV Fallopian Tube Cancer / Stage IV Ovarian Cancer / Stage IV Primary Peritoneal Cancer / Undifferentiated Ovarian Carcinoma1
Not AvailableTerminatedTreatmentOsteosarcomas1
Not AvailableTerminatedTreatmentStage I Non-Small Cell Lung Cancer / Stage II Non-Small Cell Lung Cancer1
Not AvailableWithdrawnNot AvailableCancer, Ovarian1
Pharmacoeconomics
Manufacturers
  • App pharmaceuticals llc
  • Bedford laboratories div ben venue laboratories inc
  • Hospira inc
  • Pliva inc
  • Sandoz inc
  • Watson laboratories inc
  • Watson laboratories
  • Bristol myers squibb co pharmaceutical research institute
  • Akorn inc
  • Bedford laboratories
  • Bioniche pharma usa llc
  • Ebewe pharma ges mbh nfg kg
  • Fresenius kabi oncology plc
  • Pharmachemie bv
  • Pliva lachema as
  • Spectrum pharmaceuticals inc
  • Sun pharma global inc
  • Teva parenteral medicines inc
  • Bristol myers squibb co
Packagers
Dosage forms
FormRouteStrength
InjectionIntravenous10 mg/mL
Injection, solutionIntravenous10 mg/mL
SolutionIntravenous150 mg/5mL
SolutionIntravenous450 mg/5mL
SolutionIntravenous50 mg/5mL
LiquidIntravenous10 mg
SolutionIntravenous10 mg
Powder, for solutionIntravenous150 mg
Prices
Unit descriptionCostUnit
Paraplatin 450 mg vial1474.46USD vial
Paraplatin 150 mg vial491.48USD vial
Carboplatin 150 mg vial255.31USD vial
Paraplatin 50 mg vial163.84USD vial
Carboplatin 450 mg vial156.25USD vial
Carboplatin 50 mg vial85.1USD vial
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
logP1.06ChemAxon
pKa (Strongest Basic)-6.6ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area52.6 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity29.01 m3·mol-1ChemAxon
Polarizability14.06 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption-0.6183
Blood Brain Barrier+0.8295
Caco-2 permeable-0.584
P-glycoprotein substrateNon-substrate0.6375
P-glycoprotein inhibitor INon-inhibitor0.9489
P-glycoprotein inhibitor IINon-inhibitor0.9968
Renal organic cation transporterNon-inhibitor0.9239
CYP450 2C9 substrateNon-substrate0.8745
CYP450 2D6 substrateNon-substrate0.8276
CYP450 3A4 substrateNon-substrate0.703
CYP450 1A2 substrateNon-inhibitor0.8142
CYP450 2C9 inhibitorNon-inhibitor0.854
CYP450 2D6 inhibitorNon-inhibitor0.9168
CYP450 2C19 inhibitorNon-inhibitor0.8607
CYP450 3A4 inhibitorNon-inhibitor0.6995
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9896
Ames testNon AMES toxic0.746
CarcinogenicityNon-carcinogens0.8906
BiodegradationReady biodegradable0.8235
Rat acute toxicity2.3469 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9596
hERG inhibition (predictor II)Non-inhibitor0.9767
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassDicarboxylic acids and derivatives
Direct ParentDicarboxylic acids and derivatives
Alternative Parents
Substituents
  • Dicarboxylic acid or derivatives
  • Carboxylic acid salt
  • Oxacycle
  • Organic metal salt
  • Organic transition metal salt
  • Organoheterocyclic compound
  • Metalloheterocycle
  • Organic nitrogen compound
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organic salt
  • Organooxygen compound
  • Carbonyl group
  • Aliphatic heteropolycyclic compound
Molecular FrameworkAliphatic heteropolycyclic compounds
External Descriptors

Targets

1. DNA
Kind
Nucleotide
Organism
Human
Pharmacological action
yes
Actions
cross-linking/alkylation
General Function:
Used for biological information storage.
Specific Function:
DNA contains the instructions needed for an organism to develop, survive and reproduce.
Molecular Weight:
2.15 x 1012 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Sharma S, Gong P, Temple B, Bhattacharyya D, Dokholyan NV, Chaney SG: Molecular dynamic simulations of cisplatin- and oxaliplatin-d(GG) intrastand cross-links reveal differences in their conformational dynamics. J Mol Biol. 2007 Nov 9;373(5):1123-40. Epub 2007 Aug 23. [PubMed:17900616 ]
  4. Appleton K, Mackay HJ, Judson I, Plumb JA, McCormick C, Strathdee G, Lee C, Barrett S, Reade S, Jadayel D, Tang A, Bellenger K, Mackay L, Setanoians A, Schatzlein A, Twelves C, Kaye SB, Brown R: Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. J Clin Oncol. 2007 Oct 10;25(29):4603-9. [PubMed:17925555 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inducer
General Function:
Xanthine oxidase activity
Specific Function:
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Gene Name:
XDH
Uniprot ID:
P47989
Molecular Weight:
146422.99 Da
References
  1. Husai K, Jagannathan R, Hasan Z, Trammell GL, Rybak LP, Hazelrigg SR, Somani SM: Dose response of carboplatin-induced nephrotoxicity in rats. Pharmacol Toxicol. 2002 Aug;91(2):83-9. [PubMed:12420797 ]
  2. Husain K, Whitworth C, Rybak LP: Time response of carboplatin-induced nephrotoxicity in rats. Pharmacol Res. 2004 Sep;50(3):291-300. [PubMed:15225673 ]
  3. Husain K, Whitworth C, Somani SM, Rybak LP: Carboplatin-induced oxidative stress in rat cochlea. Hear Res. 2001 Sep;159(1-2):14-22. [PubMed:11520631 ]
  4. Husain K, Whitworth C, Hazelrigg S, Rybak L: Carboplatin-induced oxidative injury in rat inferior colliculus. Int J Toxicol. 2003 Sep-Oct;22(5):335-42. [PubMed:14555405 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Peroxidase activity
Specific Function:
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Gene Name:
MPO
Uniprot ID:
P05164
Molecular Weight:
83867.71 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Glutathione transferase activity
Specific Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.
Gene Name:
GSTT1
Uniprot ID:
P30711
Molecular Weight:
27334.755 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Zinc ion binding
Specific Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Gene Name:
MT1A
Uniprot ID:
P04731
Molecular Weight:
6120.19 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Zinc ion binding
Specific Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Gene Name:
MT2A
Uniprot ID:
P02795
Molecular Weight:
6042.05 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Zinc ion binding
Specific Function:
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Gene Name:
SOD1
Uniprot ID:
P00441
Molecular Weight:
15935.685 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
S-nitrosoglutathione binding
Specific Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Gene Name:
GSTP1
Uniprot ID:
P09211
Molecular Weight:
23355.625 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Protein homodimerization activity
Specific Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Gene Name:
GSTM1
Uniprot ID:
P09488
Molecular Weight:
25711.555 Da
References
  1. Link [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Superoxide dismutase activity
Specific Function:
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Gene Name:
NQO1
Uniprot ID:
P15559
Molecular Weight:
30867.405 Da
References
  1. Link [Link]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Copper uptake transmembrane transporter activity
Specific Function:
High-affinity, saturable copper transporter involved in dietary copper uptake.
Gene Name:
SLC31A1
Uniprot ID:
O15431
Molecular Weight:
21090.545 Da
References
  1. Howell SB, Safaei R, Larson CA, Sailor MJ: Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs. Mol Pharmacol. 2010 Jun;77(6):887-94. doi: 10.1124/mol.109.063172. Epub 2010 Feb 16. [PubMed:20159940 ]
  2. Song IS, Savaraj N, Siddik ZH, Liu P, Wei Y, Wu CJ, Kuo MT: Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells. Mol Cancer Ther. 2004 Dec;3(12):1543-9. [PubMed:15634647 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Copper ion transmembrane transporter activity
Specific Function:
Involved in low-affinity copper uptake.
Gene Name:
SLC31A2
Uniprot ID:
O15432
Molecular Weight:
15681.29 Da
References
  1. Blair BG, Larson CA, Safaei R, Howell SB: Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin. Clin Cancer Res. 2009 Jul 1;15(13):4312-21. doi: 10.1158/1078-0432.CCR-09-0311. Epub 2009 Jun 9. [PubMed:19509135 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Superoxide dismutase copper chaperone activity
Specific Function:
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
Gene Name:
ATP7A
Uniprot ID:
Q04656
Molecular Weight:
163372.275 Da
References
  1. Samimi G, Katano K, Holzer AK, Safaei R, Howell SB: Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B. Mol Pharmacol. 2004 Jul;66(1):25-32. [PubMed:15213293 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Copper-exporting atpase activity
Specific Function:
Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
Gene Name:
ATP7B
Uniprot ID:
P35670
Molecular Weight:
157261.34 Da
References
  1. Samimi G, Katano K, Holzer AK, Safaei R, Howell SB: Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B. Mol Pharmacol. 2004 Jul;66(1):25-32. [PubMed:15213293 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from t...
Gene Name:
ABCG2
Uniprot ID:
Q9UNQ0
Molecular Weight:
72313.47 Da
References
  1. Ceckova M, Vackova Z, Radilova H, Libra A, Buncek M, Staud F: Effect of ABCG2 on cytotoxicity of platinum drugs: interference of EGFP. Toxicol In Vitro. 2008 Dec;22(8):1846-52. doi: 10.1016/j.tiv.2008.09.001. Epub 2008 Sep 9. [PubMed:18801423 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Organic anion transmembrane transporter activity
Specific Function:
Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Gene Name:
ABCC2
Uniprot ID:
Q92887
Molecular Weight:
174205.64 Da
References
  1. Link [Link]
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Drug created on June 13, 2005 07:24 / Updated on August 17, 2016 12:23