Uncoupling Agents
- Name
- Uncoupling Agents
- Accession Number
- DBCAT000642
- Description
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.
- Drugs
Drug Drug Description Dicoumarol For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis. Picric acid Used as antiseptic, astringent, and stimulant for epitheliazation. 2,4-Dinitrophenol A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,... Glyphosate Not Available Rotenone Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also... Monensin Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds. Ellipticine Ellipticine is a potent antineoplastic agent. - Drugs & Drug Targets