Gadolinium

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Name
Gadolinium
Accession Number
DB12091
Type
Small Molecule
Groups
Approved, Investigational
Description

Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.

Structure
Thumb
Synonyms
  • gadolinio
Product Ingredients
IngredientUNIICASInChI Key
Gadolinium ChlorideP7082WY76D10138-52-0MEANOSLIBWSCIT-UHFFFAOYSA-K
Categories
UNII
AU0V1LM3JT
CAS number
7440-54-2
Weight
Average: 157.25
Monoisotopic: 157.924100533
Chemical Formula
Gd
InChI Key
UIWYJDYFSGRHKR-UHFFFAOYSA-N
InChI
InChI=1S/Gd
IUPAC Name
gadolinium
SMILES
[Gd]

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

Learn more
Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

Learn more
Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

Learn more
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0041899
PubChem Compound
23982
PubChem Substance
347828395
ChemSpider
22418
ChEBI
33375
HET
GD
Wikipedia
Gadolinium
PDB Entries
1b9x / 1b9y / 1h87 / 1ima / 1imb / 1isr / 1v8m / 2hhm / 2p80 / 2trc
show 59 more

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0Not Yet RecruitingBasic ScienceBrain Tumor Adult1
0Not Yet RecruitingBasic ScienceSoft Tissue Sarcoma (STS)1
1Active Not RecruitingOtherChronic Obstructive Pulmonary Disease (COPD) / E-cigarettes1
1RecruitingDiagnosticLeukemias1
1RecruitingTreatmentGliomas1
1, 2Not Yet RecruitingTreatmentAbnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus / Cervical Dystonia Adults 1
1, 2Not Yet RecruitingTreatmentChronic Migraine More than15 Days Per Month, and Lasting 4 Hours a Day or Longer1
1, 2Not Yet RecruitingTreatmentIncreased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors / Upper Limb Spasticity Unilaterally in Adults With History of Stroke1
1, 2Not Yet RecruitingTreatmentPsoriasis Vulgaris (Plaque Psoriasis)1
2RecruitingDiagnosticCentral Nervous System Neoplasms / Cranial nerve disorder / Loss of Consciousness / Paresis1
2RecruitingDiagnosticMetastatic Malignant Neoplasm in the Brain / Primary Brain Neoplasms1
2, 3CompletedDiagnosticCoronary Artery Atherosclerosis / Heart Disease, Ischemic1
4CompletedDiagnosticAcute Graft Rejection / Cardiac Transplant / Chronic Graft Rejection1
4Not Yet RecruitingDiagnosticContrast Media Allergy1
4Not Yet RecruitingDiagnosticPulmonary Embolism (PE)1
4RecruitingDiagnosticMenière's Disease1
Not AvailableActive Not RecruitingDiagnosticCentral Nervous System Lymphoma / Malignant Gliomas / Metastatic Malignant Neoplasm in the Brain / Neoplasms, Brain1
Not AvailableActive Not RecruitingDiagnosticChildhood Brain Neoplasm / Recurrent Childhood Brain Neoplasm1
Not AvailableCompletedBasic ScienceCoronary Artery Disease1
Not AvailableCompletedDiagnosticAdult Brain Glioblastoma1
Not AvailableCompletedOtherAcromegaly1
Not AvailableNot Yet RecruitingNot AvailableAcute Kidney Injury (AKI) / Chronic Kidney Disease (CKD) / High Blood Pressure (Hypertension)1
Not AvailableRecruitingNot AvailableAcute Kidney Injury (AKI) / Chronic Kidney Disease (CKD) / High Blood Pressure (Hypertension)1
Not AvailableWithdrawnNot AvailableDisseminated Sclerosis1
Not AvailableWithdrawnDiagnosticGlioblastomas1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as homogeneous lanthanide compounds. These are inorganic compounds containing only metal atoms, with the largest atom being a lanthanide atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous lanthanide compounds
Sub Class
Not Available
Direct Parent
Homogeneous lanthanide compounds
Alternative Parents
Not Available
Substituents
Homogeneous lanthanide
Molecular Framework
Not Available
External Descriptors
lanthanoid atom, f-block element atom (CHEBI:33375)

Drug created on October 20, 2016 15:20 / Updated on May 01, 2019 13:22