CNV-2197944

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
CNV-2197944
Accession Number
DB15229
Type
Small Molecule
Groups
Investigational
Description

CNV-2197944 is under investigation in clinical trial NCT01893125 (Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Diabetic Peripheral Neuropathy).

Structure
Thumb
Synonyms
  • CNV2197944
Categories
Not Available
UNII
SSB9S6N20R
CAS number
1204535-44-3
Weight
Average: 427.44
Monoisotopic: 427.117747179
Chemical Formula
C19H20F3N3O3S
InChI Key
BLFJGFDZMABYMY-ZDUSSCGKSA-N
InChI
InChI=1S/C19H20F3N3O3S/c1-13-12-24(10-11-25(13)18(26)17-4-3-9-23-14(17)2)29(27,28)16-7-5-15(6-8-16)19(20,21)22/h3-9,13H,10-12H2,1-2H3/t13-/m0/s1
IUPAC Name
(2S)-2-methyl-1-(2-methylpyridine-3-carbonyl)-4-[4-(trifluoromethyl)benzenesulfonyl]piperazine
SMILES
C[C@H]1CN(CCN1C(=O)C1=CC=CN=C1C)S(=O)(=O)C1=CC=C(C=C1)C(F)(F)F

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
75531289

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentDiabetic Peripheral Neuropathy (DPN)1
2CompletedTreatmentPost-Herpetic Neuralgia (PHN)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.119 mg/mLALOGPS
logP2.34ALOGPS
logP2.16ChemAxon
logS-3.6ALOGPS
pKa (Strongest Basic)4.55ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area70.58 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity101.83 m3·mol-1ChemAxon
Polarizability40.34 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 09:02 / Updated on February 02, 2020 03:21