Dazucorilant
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Dazucorilant
- DrugBank Accession Number
- DB18025
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 582.57
Monoisotopic: 582.13487441 - Chemical Formula
- C29H22F4N4O3S
- Synonyms
- Methanone, ((4ar)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4ah-pyrazolo(3,4-g)isoquinolin-4a-yl)-2-pyridinyl-
- External IDs
- CORT-113176
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- HR4RD5RBJ6
- CAS number
- 1496508-34-9
- InChI Key
- VXOBXKQLNWYQPQ-NDEPHWFRSA-N
- InChI
- InChI=1S/C29H22F4N4O3S/c30-22-6-8-23(9-7-22)37-26-15-21-12-14-36(41(39,40)24-10-4-20(5-11-24)29(31,32)33)18-28(21,16-19(26)17-35-37)27(38)25-3-1-2-13-34-25/h1-11,13,15,17H,12,14,16,18H2/t28-/m1/s1
- IUPAC Name
- 2-[(4aR)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)benzenesulfonyl]-1H,4H,4aH,5H,6H,7H,8H-pyrido[3,4-f]indazole-4a-carbonyl]pyridine
- SMILES
- FC1=CC=C(C=C1)N1N=CC2=C1C=C1CCN(C[C@]1(C2)C(=O)C1=CC=CC=N1)S(=O)(=O)C1=CC=C(C=C1)C(F)(F)F
References
- General References
- Not Available
- External Links
- ChemSpider
- 58919795
- BindingDB
- 50265674
- ChEMBL
- CHEMBL3734774
- ZINC
- ZINC000141958834
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Recruiting Treatment Amyotrophic Lateral Sclerosis (ALS) 1 1 Completed Basic Science Healthy Adults 1 1 Completed Basic Science Healthy Volunteers (HV) 1 1 Completed Treatment Healthy Adults 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 4.91 Chemaxon pKa (Strongest Basic) 2.61 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 85.16 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 145.19 m3·mol-1 Chemaxon Polarizability 54.23 Å3 Chemaxon Number of Rings 6 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 08, 2023 00:08 / Updated at September 12, 2023 18:32