ZYIL-1
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Identification
- Generic Name
- ZYIL-1
- DrugBank Accession Number
- DB18184
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 403.54
Monoisotopic: 403.19296298 - Chemical Formula
- C21H29N3O3S
- Synonyms
- Not Available
- External IDs
- ZYIL-1
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- P9ZQS28F8C
- CAS number
- 2455519-86-3
- InChI Key
- HAMGPBKPACGWND-ZOXUKVPXSA-N
- InChI
- InChI=1S/C21H29N3O3S/c1-21(10-5-12-24(21)2)11-13-28(26,27)23-20(25)22-19-17-8-3-6-15(17)14-16-7-4-9-18(16)19/h11,13-14H,3-10,12H2,1-2H3,(H2,22,23,25)/b13-11+/t21-/m1/s1
- IUPAC Name
- 3-[(1E)-2-[(2R)-1,2-dimethylpyrrolidin-2-yl]ethenesulfonyl]-1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
- SMILES
- CN1CCC[C@]1(C)\C=C\S(=O)(=O)NC(=O)NC1=C2CCCC2=CC2=C1CCC2
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Cryopyrin-associated Periodic Syndromes (CAPS) 1 2 Recruiting Treatment Amyotrophic Lateral Sclerosis (ALS) 1 1 Completed Treatment Coronavirus Disease 2019 (COVID‑19) / Healthy Volunteers (HV) 2
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 2.33 Chemaxon pKa (Strongest Acidic) 4.62 Chemaxon pKa (Strongest Basic) 7.77 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 78.51 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 113.71 m3·mol-1 Chemaxon Polarizability 44.47 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 13, 2023 18:40 / Updated at September 15, 2023 10:38