Emlenoflast
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Emlenoflast
- DrugBank Accession Number
- DB18304
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 388.49
Monoisotopic: 388.156911823 - Chemical Formula
- C19H24N4O3S
- Synonyms
- 1h-pyrazole-3-sulfonamide, n-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)carbonyl)-1-(1-methylethyl)-
- Inzomelid
- N-[[(1,2,3,5,6,7-HEXAHYDRO-S-INDACEN-4-YL) AMINO]CARBONYL]-1-(1-METHYLETHYL)-1H-PYRAZOLE-3-SULFONAMIDE
- External IDs
- IZD-174
- IZD174
- MCC-7840
- MCC7840
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- SC4RYG0M76
- CAS number
- 1995067-59-8
- InChI Key
- MTOUOUSKXWSTAX-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H24N4O3S/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18/h9-12H,3-8H2,1-2H3,(H2,20,22,24)
- IUPAC Name
- 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-{[1-(propan-2-yl)-1H-pyrazol-3-yl]sulfonyl}urea
- SMILES
- CC(C)N1C=CC(=N1)S(=O)(=O)NC(=O)NC1=C2CCCC2=CC2=C1CCC2
References
- General References
- Not Available
- External Links
- ChemSpider
- 98854691
- ChEMBL
- CHEMBL4650350
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1 Completed Other Healthy Volunteers (HV) 1 1 Withdrawn Basic Science Parkinson's Disease (PD) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 4.29 Chemaxon pKa (Strongest Acidic) 5.04 Chemaxon pKa (Strongest Basic) -1.6 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 93.09 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 117.06 m3·mol-1 Chemaxon Polarizability 41.07 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 15, 2023 22:15 / Updated at September 17, 2023 04:16