Parkinson's Disease (PD)

Also known as: Parkinson's Syndrome / Parkinson Disease (PK) / Parkinson's Disease / Parkinson Disease(PD) / Parkinson Disease / Parkinson's / Parkinson's dis / Shaking palsy / Hemiparkinsonism / Palsy shaking / Paralysis agitans / Disease Parkinson's / Parkinson's disease NOS / Syndrome Parkinson's

DrugDrug NameDrug Description
DB00915AmantadineAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake. [PubChem]
DB00714ApomorphineA derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.
DB01200BromocriptineBromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It is indicated for the management of signs and symptoms of Parkinsonian Syndrome. Bromocriptine also inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. It also causes sustained suppression of somatotropin (growth hormone) secretion in some patients with acromegaly. Bromocriptine has been associated with pulmonary fibrosis.
DB00190CarbidopaAn inhibitor of DOPA decarboxylase, preventing conversion of levodopa to dopamine. It is used in parkinson disease to reduce peripheral adverse effects of levodopa. It has no antiparkinson actions by itself. [PubChem]
DB06262DroxidopaDroxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a deficit of noradrenaline as well as of dopamine in Parkinson's disease and it has been proposed that this underlies the sudden transient freezing seen usually in advanced disease. Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout Europe. Provided L-DOPS successfully completes clinical trials, it could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. Additionally, phase II clinical trials for intradialytic hypotension are also underway. Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the pharmaceutical company developing it in that country.
DB00494EntacaponeEntacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa and a decarboxylase inhibitor.
DB00392EthopropazineEthopropazine (also known as profenamine hydrochloride) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat parkinsonism. It is sold under the trade names Parsidol in the United States and Parsidan in Canada.
DB00674GalantamineA benzazepine derived from norbelladine. It is found in galanthus and other amaryllidaceae. Galantamine is a cholinesterase inhibitor that has been used to reverse the muscular effects of gallamine triethiodide and tubocurarine, and has been studied as a treatment for Alzheimer's disease and other central nervous system disorders.
DB01235LevodopaThe naturally occurring form of dihydroxyphenylalanine and the immediate precursor of dopamine. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to dopamine. It is used for the treatment of parkinsonian disorders and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
DB01224QuetiapineQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
DB01367RasagilineRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
DB00268RopiniroleRopinirole is a non-ergoline dopamine agonist, manufactured by GlaxoSmithKline. It is used in the treatment of Parkinson's disease, and is also one of two medications in the United States with an FDA-approved indication for the treatment of restless legs syndrome (the other being Pramipexole).
DB05271RotigotineRotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. Like other dopamine agonists, rotigotine has been shown to possess antidepressant effects and may be useful in the treatment of depression as well. Rotigotine was developed by Aderis Pharmaceuticals. In 1998, Aderis licensed worldwide development and commercialization rights for rotigotine to the German pharmaceutical company Schwarz Pharma (today a subsidiary of the Belgian company UCB S.A.). The drug has been approved by the EMEA for use in Europe in 2006 and is today being sold in several European countries. In 2007, the Neupro patch was approved by the Food and Drug Administration (FDA) as the first transdermal treatment of Parkinson's disease in the United States. However, as of 2008, Schwarz Pharma has recalled all Neupro patches in the United States and some in Europe because of problems with the delivery mechanism. Rotigotine has been authorized as a treatment for RLS since August 2008.
DB06654SafinamideSafinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
DB01037SelegilineA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
DrugDrug NameTargetType
DB00915AmantadineD(2) dopamine receptortarget
DB00915AmantadineMatrix protein 2target
DB00915AmantadineAromatic-L-amino-acid decarboxylaseenzyme
DB00915AmantadineAmine oxidase [flavin-containing] Benzyme
DB00915AmantadineSolute carrier family 22 member 2transporter
DB00915AmantadineSolute carrier family 22 member 1transporter
DB00915AmantadineMultidrug resistance protein 1transporter
DB00915AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
DB00714ApomorphineD(2) dopamine receptortarget
DB00714ApomorphineD(1A) dopamine receptortarget
DB00714ApomorphineD(4) dopamine receptortarget
DB00714ApomorphineD(3) dopamine receptortarget
DB00714ApomorphineD(1B) dopamine receptortarget
DB00714ApomorphineNeuron-specific vesicular protein calcyontarget
DB00714ApomorphineAlpha-2C adrenergic receptortarget
DB00714ApomorphineAlpha-2B adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Ctarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Btarget
DB00714ApomorphineAlpha-2A adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Dtarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Btarget
DB00714ApomorphineCytochrome P450 1A2enzyme
DB01200BromocriptineD(2) dopamine receptortarget
DB01200BromocriptineCytochrome P450 3A4enzyme
DB01200Bromocriptine5-hydroxytryptamine receptor 1Dtarget
DB01200BromocriptineAlpha-2A adrenergic receptortarget
DB01200BromocriptineD(3) dopamine receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Atarget
DB01200BromocriptineAlpha-2C adrenergic receptortarget
DB01200BromocriptineAlpha-2B adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Btarget
DB01200BromocriptineD(4) dopamine receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Atarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Btarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Ctarget
DB01200BromocriptineD(1B) dopamine receptortarget
DB01200BromocriptineD(1A) dopamine receptortarget
DB01200BromocriptineAlpha-1A adrenergic receptortarget
DB01200BromocriptineAlpha-1B adrenergic receptortarget
DB01200BromocriptineAlpha-1D adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 7target
DB01200BromocriptineMultidrug resistance protein 1transporter
DB01200BromocriptineCytochrome P450 1A2enzyme
DB00190CarbidopaAromatic-L-amino-acid decarboxylasetarget
DB06262DroxidopaPhenylalanine-4-hydroxylasetarget
DB06262DroxidopaAlpha-1A adrenergic receptortarget
DB06262DroxidopaAlpha-1B adrenergic receptortarget
DB06262DroxidopaAlpha-1D adrenergic receptortarget
DB06262DroxidopaAlpha-2A adrenergic receptortarget
DB06262DroxidopaAlpha-2B adrenergic receptortarget
DB06262DroxidopaAlpha-2C adrenergic receptortarget
DB06262DroxidopaBeta-1 adrenergic receptortarget
DB06262DroxidopaBeta-2 adrenergic receptortarget
DB06262DroxidopaBeta-3 adrenergic receptortarget
DB06262DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DB06262DroxidopaMonocarboxylate transporter 10transporter
DB06262DroxidopaSodium-dependent noradrenaline transportertransporter
DB00494EntacaponeCatechol O-methyltransferasetarget
DB00494EntacaponeCatechol O-methyltransferaseenzyme
DB00494EntacaponeUDP-glucuronosyltransferase 1-9enzyme
DB00494EntacaponeCytochrome P450 1A2enzyme
DB00494EntacaponeCytochrome P450 2D6enzyme
DB00392EthopropazineGlutamate receptor ionotropic, NMDA 3Atarget
DB00392EthopropazineMuscarinic acetylcholine receptor M1target
DB00392EthopropazineCholinesteraseenzyme
DB00392EthopropazineMuscarinic acetylcholine receptor M2target
DB00674GalantamineAcetylcholinesterasetarget
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00674GalantamineCholinesterasetarget
DB01235LevodopaD(1A) dopamine receptortarget
DB01235LevodopaD(2) dopamine receptortarget
DB01235LevodopaAromatic-L-amino-acid decarboxylaseenzyme
DB01235LevodopaSolute carrier family 15 member 1transporter
DB01235LevodopaMonocarboxylate transporter 10transporter
DB01235LevodopaD(3) dopamine receptortarget
DB01235LevodopaD(4) dopamine receptortarget
DB01235LevodopaD(1B) dopamine receptortarget
DB01235LevodopaCytochrome P450 2D6enzyme
DB01235LevodopaLarge neutral amino acids transporter small subunit 1transporter
DB01235LevodopaLarge neutral amino acids transporter small subunit 2transporter
DB01224Quetiapine5-hydroxytryptamine receptor 2Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Ctarget
DB01224QuetiapineD(2) dopamine receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Atarget
DB01224QuetiapineHistamine H1 receptortarget
DB01224QuetiapineCytochrome P450 3A4enzyme
DB01224QuetiapineAlpha-1A adrenergic receptortarget
DB01224QuetiapineAlpha-1B adrenergic receptortarget
DB01224QuetiapineAlpha-1D adrenergic receptortarget
DB01224QuetiapineAlpha-2A adrenergic receptortarget
DB01224QuetiapineAlpha-2B adrenergic receptortarget
DB01224QuetiapineAlpha-2C adrenergic receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Dtarget
DB01224QuetiapineMuscarinic acetylcholine receptor M1target
DB01224QuetiapineMuscarinic acetylcholine receptor M2target
DB01224QuetiapineMuscarinic acetylcholine receptor M3target
DB01224QuetiapineMuscarinic acetylcholine receptor M4target
DB01224QuetiapineMuscarinic acetylcholine receptor M5target
DB01224Quetiapine5-hydroxytryptamine receptor 1Btarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Etarget
DB01224Quetiapine5-hydroxytryptamine receptor 3Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 6target
DB01224Quetiapine5-hydroxytryptamine receptor 7target
DB01224QuetiapineD(1B) dopamine receptortarget
DB01224QuetiapineD(1A) dopamine receptortarget
DB01224QuetiapineD(3) dopamine receptortarget
DB01224QuetiapineD(4) dopamine receptortarget
DB01224QuetiapineCytochrome P450 3A5enzyme
DB01224QuetiapineCytochrome P450 3A7enzyme
DB01224QuetiapineMultidrug resistance protein 1transporter
DB01224QuetiapineCytochrome P450 2C19enzyme
DB01224QuetiapineCytochrome P450 2D6enzyme
DB01367RasagilineApoptosis regulator Bcl-2target
DB01367RasagilineAmine oxidase [flavin-containing] Btarget
DB01367RasagilineCytochrome P450 1A2enzyme
DB00268RopiniroleD(2) dopamine receptortarget
DB00268RopiniroleD(3) dopamine receptortarget
DB00268RopiniroleD(4) dopamine receptortarget
DB00268RopiniroleCytochrome P450 1A2enzyme
DB00268Ropinirole5-hydroxytryptamine receptor 1Atarget
DB00268Ropinirole5-hydroxytryptamine receptor 1Dtarget
DB00268Ropinirole5-hydroxytryptamine receptor 2Btarget
DB00268Ropinirole5-hydroxytryptamine receptor 1Btarget
DB00268Ropinirole5-hydroxytryptamine receptor 2Atarget
DB00268Ropinirole5-hydroxytryptamine receptor 2Ctarget
DB00268RopiniroleAlpha-2A adrenergic receptortarget
DB00268RopiniroleAlpha-2B adrenergic receptortarget
DB00268RopiniroleAlpha-2C adrenergic receptortarget
DB00268RopiniroleD(1A) dopamine receptortarget
DB00268RopiniroleD(1B) dopamine receptortarget
DB00268RopiniroleCytochrome P450 2D6enzyme
DB00268RopiniroleCytochrome P450 3A4enzyme
DB05271RotigotineD(3) dopamine receptortarget
DB05271RotigotineD(1B) dopamine receptortarget
DB05271RotigotineD(4) dopamine receptortarget
DB05271RotigotineD(2) dopamine receptortarget
DB05271Rotigotine5-hydroxytryptamine receptor 1Atarget
DB05271RotigotineD(1A) dopamine receptortarget
DB05271RotigotineCytochrome P450 1A2enzyme
DB05271RotigotineCytochrome P450 2D6enzyme
DB05271RotigotineCytochrome P450 3A4enzyme
DB05271RotigotineAlpha-2B adrenergic receptortarget
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB01037SelegilineAmine oxidase [flavin-containing] Btarget
DB01037SelegilineCytochrome P450 2B6enzyme
DB01037SelegilineAmine oxidase [flavin-containing] Atarget
DB01037SelegilineCytochrome P450 2A6enzyme
DB01037SelegilineCytochrome P450 3A4enzyme
DB01037SelegilineMultidrug resistance protein 1transporter
DB01037SelegilineCytochrome P450 1A2enzyme
DB01037SelegilineCytochrome P450 2C19enzyme
DB01037SelegilineCytochrome P450 2C8enzyme
DB01037SelegilineCytochrome P450 2C9enzyme
DB01037SelegilineCytochrome P450 2D6enzyme
DB01037SelegilineCytochrome P450 2E1enzyme
DrugDrug NamePhaseStatusCount
DB01142Doxepin0Completed1
DB00745Modafinil0Enrolling by Invitation1
DB01198Zopiclone0Completed1
DB05196ACR3251Completed1
DB00316Acetaminophen1Completed1
DB06151Acetylcysteine1Completed1
DB12783Benserazide1Completed3
DB00083Botulinum Toxin Type A1Not Yet Recruiting1
DB00083Botulinum Toxin Type A1Recruiting1
DB00490Buspirone1Recruiting1
DB00190Carbidopa1Completed19
DB11121Chloroxylenol1Recruiting1
DB11292Docosahexaenoate1Completed1
DB01184Domperidone1Completed1
DB06262Droxidopa1Recruiting1
DB00494Entacapone1Completed7
DB00016Erythropoietin1Completed1
DB09149Florbetapir (18F)1Completed1
DB00687Fludrocortisone1Completed1
DB13134Fluorine F-181Completed1
DB00143Glutathione1Completed1
DB08909Glycerol Phenylbutyrate1Active Not Recruiting1
DB11757Istradefylline1Completed1
DB01235Levodopa1Completed20
DB00211Midodrine1Recruiting1
DB00218Moxifloxacin1Completed2
DB12458Muscimol1Withdrawn1
DB04868Nilotinib1Completed1
DB05450PYM500281Completed1
DB00413Pramipexole1Completed1
DB01708Prasterone1Completed1
DB11864Preladenant1Completed2
DB01367Rasagiline1Completed4
DB00912Repaglinide1Completed1
DB02709Resveratrol1Completed4
DB01045Rifampicin1Completed1
DB00268Ropinirole1Completed1
DB05271Rotigotine1Completed6
DB00020Sargramostim1Completed1
DB01586Ursodeoxycholic acid1Not Yet Recruiting1
DB11806VTP-1942041Completed1
DB00682Warfarin1Completed2
DB06151Acetylcysteine1 / 2Completed1
DB06774Capsaicin1 / 2Completed1
DB00190Carbidopa1 / 2Completed3
DB00190Carbidopa1 / 2Terminated1
DB00190Carbidopa1 / 2Unknown Status1
DB06637Dalfampridine1 / 2Completed1
DB06262Droxidopa1 / 2Terminated1
DB00494Entacapone1 / 2Completed1
DB00494Entacapone1 / 2Terminated1
DB09149Florbetapir (18F)1 / 2Completed1
DB01235Levodopa1 / 2Completed2
DB01235Levodopa1 / 2Unknown Status1
DB05914Mesenchymal Stem Cells1 / 2Unknown Status1
DB00184Nicotine1 / 2Completed1
DB00268Ropinirole1 / 2Recruiting1
DB01104Sertraline1 / 2Active Not Recruiting1
DB04982Talampanel1 / 2Completed1
DB06151Acetylcysteine2Completed1
DB04947Altropane2Completed1
DB00915Amantadine2Recruiting1
DB00915Amantadine2Terminated1
DB06742Ambroxol2Not Yet Recruiting1
DB00714Apomorphine2Completed5
DB00714Apomorphine2Recruiting4
DB00714Apomorphine2Withdrawn1
DB11887Arundic acid2Completed1
DB00289Atomoxetine2Completed1
DB12299Bavisant2Not Yet Recruiting1
DB00083Botulinum Toxin Type A2Recruiting1
DB00083Botulinum Toxin Type A2Withdrawn1
DB00490Buspirone2Recruiting1
DB00201Caffeine2Completed1
DB09061Cannabidiol2Recruiting1
DB00190Carbidopa2Active Not Recruiting1
DB00190Carbidopa2Completed14
DB00190Carbidopa2Recruiting1
DB00190Carbidopa2Withdrawn1
DB00169Cholecalciferol2Completed1
DB01068Clonazepam2Not Yet Recruiting1
DB00286Conjugated estrogens2Completed1
DB00148Creatine2Completed1
DB08826Deferiprone2Recruiting2
DB08826Deferiprone2Unknown Status1
DB00514Dextromethorphan2Completed2
DB12733Dipraglurant2Completed1
DB01184Domperidone2Completed1
DB01184Domperidone2Terminated1
DB00843Donepezil2Not Yet Recruiting1
DB00843Donepezil2Recruiting3
DB06262Droxidopa2Enrolling by Invitation1
DB06262Droxidopa2Recruiting1
DB00476Duloxetine2Not Yet Recruiting1
DB12869Eliprodil2Completed1
DB00494Entacapone2Completed4
DB00494Entacapone2Recruiting1
DB01276Exenatide2Completed1
DB01276Exenatide2Unknown Status1
DB00099Filgrastim2Terminated1
DB09149Florbetapir (18F)2Completed1
DB09150Fludeoxyglucose F-182Completed1
DB05814GPI-14852Completed2
DB00143Glutathione2Completed2
DB09462Glycerin2Completed1
DB00986Glycopyrronium2Recruiting1
DB00741Hydrocortisone2Recruiting1
DB04335Inosine2Completed1
DB00030Insulin Human2Completed1
DB08824Ioflupane I-1232Completed1
DB08824Ioflupane I-1232Recruiting1
DB00332Ipratropium bromide2Completed1
DB00677Isoflurophate2Recruiting1
DB00270Isradipine2Completed2
DB11757Istradefylline2Completed7
DB00125L-Arginine2Completed1
DB01235Levodopa2Active Not Recruiting1
DB01235Levodopa2Completed24
DB01235Levodopa2Recruiting1
DB01235Levodopa2Unknown Status1
DB01235Levodopa2Withdrawn1
DB06655Liraglutide2Recruiting1
DB00227Lovastatin2Recruiting1
DB01065Melatonin2Not Yet Recruiting1
DB01065Melatonin2Unknown Status1
DB00422Methylphenidate2Completed1
DB01017Minocycline2Completed1
DB05063Mitoquinone2Completed1
DB00745Modafinil2Not Yet Recruiting1
DB00218Moxifloxacin2Recruiting1
DB00184Nicotine2Active Not Recruiting1
DB04868Nilotinib2Recruiting1
DB00540Nortriptyline2Completed1
DB05450PYM500282Completed1
DB00715Paroxetine2Completed1
DB08883Perampanel2Completed2
DB08883Perampanel2Terminated3
DB08883Perampanel2Withdrawn1
DB12361Piclozotan2Completed1
DB05316Pimavanserin2Completed2
DB01132Pioglitazone2Completed1
DB00413Pramipexole2Completed1
DB00413Pramipexole2Unknown Status1
DB11864Preladenant2Completed3
DB00908Quinidine2Completed1
DB12678Relamorelin2Terminated1
DB00268Ropinirole2Completed1
DB05271Rotigotine2Completed5
DB05271Rotigotine2Terminated1
DB06654Safinamide2Completed1
DB06654Safinamide2Terminated1
DB12351Siagoside2Completed1
DB00203Sildenafil2Terminated1
DB00641Simvastatin2Recruiting1
DB09153Sodium Chloride2Completed1
DB04982Talampanel2Completed2
DB00273Topiramate2Terminated1
DB12203Tozadenant2Completed1
DB09270Ubidecarenone2Completed2
DB11340Ubiquinol2Completed1
DB13196Valerian2Completed1
DB01273Varenicline2Enrolling by Invitation1
DB01273Varenicline2Recruiting1
DB11917Vatiquinone2Completed1
DB12440Verdiperstat2Completed1
DB00425Zolpidem2Withdrawn1
DB00118Ademetionine2 / 3Completed1
DB00915Amantadine2 / 3Completed1
DB00714Apomorphine2 / 3Completed1
DB05403CEP-13472 / 3Terminated1
DB00201Caffeine2 / 3Completed1
DB08826Deferiprone2 / 3Completed1
DB00633Dexmedetomidine2 / 3Withdrawn1
DB01175Escitalopram2 / 3Completed1
DB11757Istradefylline2 / 3Completed1
DB01235Levodopa2 / 3Completed1
DB01235Levodopa2 / 3Recruiting1
DB00413Pramipexole2 / 3Completed1
DB01220Rifaximin2 / 3Recruiting1
DB05271Rotigotine2 / 3Completed1
DB00909Zonisamide2 / 3Unknown Status1
DB00915Amantadine3Active Not Recruiting1
DB00915Amantadine3Completed2
DB00915Amantadine3Recruiting2
DB00915Amantadine3Terminated1
DB01060Amoxicillin3Unknown Status1
DB00714Apomorphine3Active Not Recruiting2
DB00714Apomorphine3Completed4
DB00714Apomorphine3Recruiting2
DB12783Benserazide3Completed2
DB00083Botulinum Toxin Type A3Completed1
DB01200Bromocriptine3Completed2
DB00201Caffeine3Completed1
DB00190Carbidopa3Completed7
DB00190Carbidopa3Recruiting2
DB01211Clarithromycin3Unknown Status1
DB00148Creatine3Terminated1
DB00843Donepezil3Terminated1
DB06262Droxidopa3Completed1
DB06262Droxidopa3Terminated1
DB00476Duloxetine3Completed1
DB00494Entacapone3Completed4
DB00402Eszopiclone3Completed1
DB04335Inosine3Recruiting1
DB08824Ioflupane I-1233Withdrawn1
DB00270Isradipine3Active Not Recruiting1
DB11757Istradefylline3Completed7
DB11757Istradefylline3Terminated1
DB01235Levodopa3Completed9
DB01235Levodopa3Recruiting2
DB00742Mannitol3Terminated1
DB00338Omeprazole3Unknown Status1
DB12061Pardoprunox3Completed1
DB00715Paroxetine3Completed1
DB08883Perampanel3Completed2
DB08883Perampanel3Terminated3
DB00413Pramipexole3Completed10
DB11864Preladenant3Completed2
DB11864Preladenant3Terminated2
DB01367Rasagiline3Completed11
DB01367Rasagiline3Terminated2
DB01220Rifaximin3Completed1
DB00989Rivastigmine3Completed1
DB00268Ropinirole3Completed5
DB00268Ropinirole3Unknown Status1
DB05271Rotigotine3Completed8
DB05271Rotigotine3Recruiting1
DB05271Rotigotine3Terminated1
DB06654Safinamide3Completed4
DB01591Solifenacin3Not Yet Recruiting1
DB00285Venlafaxine3Completed1
DB00915Amantadine4Completed2
DB00714Apomorphine4Completed1
DB00714Apomorphine4Recruiting2
DB00714Apomorphine4Terminated1
DB01238Aripiprazole4Completed1
DB00289Atomoxetine4Completed1
DB00289Atomoxetine4Unknown Status1
DB00083Botulinum Toxin Type A4Active Not Recruiting1
DB00083Botulinum Toxin Type A4Terminated1
DB01200Bromocriptine4Completed2
DB00248Cabergoline4Completed1
DB00248Cabergoline4Terminated1
DB00190Carbidopa4Completed7
DB00190Carbidopa4Recruiting2
DB00190Carbidopa4Terminated1
DB00190Carbidopa4Withdrawn1
DB03929D-Serine4Completed1
DB00035Desmopressin4Terminated1
DB00633Dexmedetomidine4Completed2
DB00633Dexmedetomidine4Not Yet Recruiting1
DB00843Donepezil4Completed1
DB00843Donepezil4Not Yet Recruiting1
DB00843Donepezil4Unknown Status1
DB06262Droxidopa4Recruiting2
DB00494Entacapone4Completed6
DB00494Entacapone4Terminated1
DB00494Entacapone4Withdrawn1
DB06702Fesoterodine4Recruiting1
DB08824Ioflupane I-1234Unknown Status1
DB01202Levetiracetam4Completed1
DB01202Levetiracetam4Withdrawn1
DB01235Levodopa4Completed11
DB01235Levodopa4Recruiting2
DB01235Levodopa4Terminated1
DB01235Levodopa4Withdrawn1
DB01046Lubiprostone4Completed1
DB01065Melatonin4Enrolling by Invitation2
DB01043Memantine4Completed2
DB00422Methylphenidate4Completed2
DB00422Methylphenidate4Terminated1
DB08893Mirabegron4Recruiting1
DB00704Naltrexone4Completed1
DB00184Nicotine4Unknown Status1
DB00413Pramipexole4Completed8
DB00413Pramipexole4Unknown Status1
DB00818Propofol4Completed1
DB01224Quetiapine4Completed1
DB00980Ramelteon4Terminated1
DB01367Rasagiline4Completed9
DB01367Rasagiline4Terminated1
DB01367Rasagiline4Unknown Status3
DB00989Rivastigmine4Completed1
DB00989Rivastigmine4Recruiting1
DB00989Rivastigmine4Unknown Status1
DB00268Ropinirole4Completed2
DB05271Rotigotine4Completed1
DB05271Rotigotine4Recruiting1
DB01037Selegiline4Completed2
DB01037Selegiline4Recruiting1
DB09153Sodium Chloride4Completed1
DB01591Solifenacin4Withdrawn1
DB00820Tadalafil4Recruiting1
DB00323Tolcapone4Completed1
DB00662Trimethobenzamide4Completed2
DB01273Varenicline4Active Not Recruiting1
DB00909Zonisamide4Recruiting1
DB00659AcamprosateNot AvailableWithdrawn1
DB00915AmantadineNot AvailableRecruiting1
DB00915AmantadineNot AvailableTerminated1
DB00915AmantadineNot AvailableUnknown Status1
DB00714ApomorphineNot AvailableCompleted1
DB00289AtomoxetineNot AvailableUnknown Status1
DB00248CabergolineNot AvailableCompleted1
DB00190CarbidopaNot AvailableCompleted2
DB00190CarbidopaNot AvailableRecruiting3
DB00363ClozapineNot AvailableCompleted1
DB00496DarifenacinNot AvailableCompleted1
DB08826DeferiproneNot AvailableActive Not Recruiting1
DB01184DomperidoneNot AvailableCompleted1
DB00843DonepezilNot AvailableCompleted1
DB06262DroxidopaNot AvailableRecruiting1
DB00494EntacaponeNot AvailableRecruiting2
DB00199ErythromycinNot AvailableCompleted1
DB00099FilgrastimNot AvailableCompleted1
DB00674GalantamineNot AvailableUnknown Status1
DB09341GlucoseNot AvailableCompleted1
DB08824Ioflupane I-123Not AvailableCompleted1
DB00753IsofluraneNot AvailableTerminated1
DB01235LevodopaNot AvailableCompleted4
DB01235LevodopaNot AvailableRecruiting3
DB01235LevodopaNot AvailableWithdrawn1
DB00281LidocaineNot AvailableCompleted1
DB01046LubiprostoneNot AvailableTerminated1
DB01043MemantineNot AvailableCompleted2
DB00422MethylphenidateNot AvailableWithdrawn1
DB00211MidodrineNot AvailableRecruiting1
DB00745ModafinilNot AvailableWithdrawn1
DB01062OxybutyninNot AvailableCompleted1
DB01186PergolideNot AvailableNo Longer Available1
DB12478PiribedilNot AvailableCompleted3
DB00413PramipexoleNot AvailableCompleted9
DB00413PramipexoleNot AvailableRecruiting1
DB00818PropofolNot AvailableTerminated1
DB12518RacloprideNot AvailableCompleted1
DB00980RamelteonNot AvailableWithdrawn1
DB01367RasagilineNot AvailableActive Not Recruiting1
DB01367RasagilineNot AvailableCompleted2
DB01367RasagilineNot AvailableRecruiting2
DB00899RemifentanilNot AvailableTerminated1
DB00268RopiniroleNot AvailableCompleted2
DB00268RopiniroleNot AvailableRecruiting1
DB05271RotigotineNot AvailableUnknown Status1
DB01104SertralineNot AvailableUnknown Status1
DB09072Sodium oxybateNot AvailableCompleted1
DB00323TolcaponeNot AvailableRecruiting1
DB00273TopiramateNot AvailableTerminated1