KUS-121 free acid
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- KUS-121 free acid
- DrugBank Accession Number
- DB18510
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 436.46
Monoisotopic: 436.10053976 - Chemical Formula
- C22H17FN4O3S
- Synonyms
- 1-Naphthalenesulfonic acid, 4-amino-3-[2-[6-(4-fluoro-2-methylphenyl)-3-pyridinyl]diazenyl]-
- 4-Amino-3-[[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]azo]naphthalene-1-sulfonic acid
- KUS 121 free acid
- KUS121 free acid
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key KUS-121 92Q3DLG6TH Not Available OEEZHMGRDYLKGJ-JGUILPGDSA-M KUS-121 dihydrate 79A6RUR6P3 2603172-24-1 XQCRGFXGQWMWGH-DTBIJOOYSA-M
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- KWL59W4L66
- CAS number
- 1357245-09-0
- InChI Key
- QOLHSSNEBRFIEQ-CYYJNZCTSA-N
- InChI
- InChI=1S/C22H17FN4O3S/c1-13-10-14(23)6-8-16(13)19-9-7-15(12-25-19)26-27-20-11-21(31(28,29)30)17-4-2-3-5-18(17)22(20)24/h2-12H,24H2,1H3,(H,28,29,30)/b27-26+
- IUPAC Name
- 4-amino-3-[(1E)-2-[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]diazen-1-yl]naphthalene-1-sulfonic acid
- SMILES
- CC1=CC(F)=CC=C1C1=CC=C(C=N1)\N=N\C1=C(N)C2=CC=CC=C2C(=C1)S(O)(=O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 76746066
- ChEMBL
- CHEMBL3990266
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Recruiting Treatment Central Retinal Artery Occlusion 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 2.63 Chemaxon pKa (Strongest Acidic) -2.8 Chemaxon pKa (Strongest Basic) 1.67 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 118 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 120.02 m3·mol-1 Chemaxon Polarizability 44.7 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 27, 2023 20:23 / Updated at April 29, 2024 00:51