Sulfur Acids

Inorganic or organic acids that contain sulfur as an integral part of the molecule.
DrugDrug NameDrug Indication
DB00258Calcium acetateCalcium acetate is one of a number of calcium salts used to treat hyperphosphatemia (too much phosphate in the blood) in patients with kidney disease.
DB00464Sodium Tetradecyl SulfateFor the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.
DB00653Magnesium sulfateUsed for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
DB00659AcamprosateFor the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation
DB00686Pentosan PolysulfateFor the relief of bladder pain or discomfort associated with interstitial cystitis.
DB00815Sodium lauryl sulfateSLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.
DB01008BusulfanFor use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous (myeloid, myelocytic, granulocytic) leukemia (FDA has designated busulfan as an orphan drug for this use). It is also used as a component of pretransplant conditioning regimens in patients undergoing bone marrow transplantation for acute myeloid leukemia and nonmalignant diseases.
DB03120Para-Toluene SulfonateNot Available
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidNot Available
DB03309N-CyclohexyltaurineNot Available
DB03635Ethanesulfonic AcidNot Available
DB03656Tribenuron MethylNot Available
DB03967Dodecyl sulfateNot Available
DB04348Taurocholic AcidNot Available
DB04640Naphthalene-2,6-disulfonic acidNot Available
DB04786SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
DB05377ChlorfensonInvestigated for use/treatment in fungal infections.
DB05385PRO 2000Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection.
DB06231CaldaretInvestigated for use/treatment in heart disease and myocardial infarction.
DB06442AvasimibeInvestigated for use/treatment in peripheral vascular disease.
DB06527TramiprosateInvestigated for use/treatment in strokes and alzheimer's disease.
DB06536TesaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
DB06757ManganeseIndicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
DB06778Cupric sulfateElemental use in copper deficiency [L1823] Copper and copper containing compounds are broadly used in medical practice. Metallic copper is used already for many years in dental fillings and in copper intrauterine devices (IUD) for reversible contraception. Ointments containing copper, which release copper ions that are absorbed by the skin in the management of cramps, disturbances of renal function, peripheral, venous hypostatic circulatory disturbances, rheumatic disease and swelling associated with trauma. There are also cosmetic facial creams containing copper as their main active ingredient [L1828].
DB08834Tauroursodeoxycholic acidUsed in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
DB09087Potassium alumPotassium alum is considered safe by the FDA and its use is in homepathic or OTC products. Due to its presence in several different drugs, the main indications for the use of potassium alum are: -Constipation[L1071] -Cosmetic or drug astringent, helping the shrinkage of tissues and the dry of secretions[L1072] -Oral health care drug[L1072] -Part of formulation in cleansing products, skin-care products, mosturizers, face powders and deodorants[L1073] -Antiperspirant[L1074] -Antifungal[L1074]
DB09110Coenzyme MMesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis. (2)
DB09158Trypan blue free acidTrypan blue is indicated for use as an aid in ophthalmic surgery by staining the epiretinal membranes during ophthalmic surgical vitrectomy procedures, facilitating removal of the tissue.
DB09322Zinc sulfateThis medication is a mineral used to treat or prevent low levels of zinc. In medicine it is used together with oral rehydration therapy (ORT) and an astringent. Zinc Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for TPN.
DB09472Sodium sulfateindicated for bowel cleansing prior to colonoscopy or barium enema X-ray examination.
DB09499Thiosulfuric acidAntidote: Sodium thiosulfate is indicated to counteract or neutralize actions of poisons, e.g. cyanide poisoning. Antineoplastic adjunct:
DB09534EcamsuleApplied topically to filter out UVA rays.
DB11115EnsulizoleIndicated to be used as an UV-B-absorbing molecule in sunscreen formulations.
DB11150Barium sulfate Barium sulfate is a radiographic contrast agent indicated for use in computed tomography (CT) of the abdomen to delineate the gastrointestinal (GI) tract in adult and pediatric patients [FDA label].
DB11183Light green SF yellowishNot Available
DB11239Aluminum sulfateSolutions containing 5 to 10% aluminum sulfate have been used as local applications to ulcers and to arrest foul discharges from mucous surfaces. Aluminum sulfate is also used in the preparation of aluminum acetate ear drops [L2149]. It is often purchased over the counter and is available in solid stick or powder form for minor cuts and abrasions after shaving [L2157], [L2164]. Aluminum sulfate is also used as an adjuvant in vaccines [L2158].
DB11678TreosulfanNot Available
DB11780AllicinNot Available
DB12197AuricloseneNot Available
DB12473TaurolidineNot Available
DB13107QGC-001Not Available
DB13529Dobesilic acidNot Available
DB13885Ferric subsulfateNot Available
DB14499Potassium sulfatePotassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.
DB06405EprodisateInvestigated for use/treatment in amyloidosis.
DB14667Phenyl hydrogen sulfateNot Available
DB01956TaurineThe use of diet supplements containing taurine is indicated for the nutritional support of infants and young pediatric patients requiring total parenteral nutrition via central or peripheral routes. The usage of diet supplements containing taurine prevents nitrogen and weight loss or to treat negative nitrogen balance in pediatric patients where the alimentary tract cannot be done through oral, gastrostomy or jejunostomy administration, there is impaired gastrointestinal absorption or protein requirements are substantially increased.[FDA label]
DB02292IrosustatNot Available
DB03848Benzenesulfinic acidNot Available
DrugDrug NameTargetType
DB00258Calcium acetatePhosphatetarget
DB00464Sodium Tetradecyl SulfateVitamin K-dependent protein Ctarget
DB00464Sodium Tetradecyl SulfateVitamin K-dependent protein Starget
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00659AcamprosateMetabotropic glutamate receptor 5target
DB00659AcamprosateProton-coupled amino acid transporter 1transporter
DB00659AcamprosateGABA-A receptor (anion channel)target
DB00659AcamprosateGlutamate (NMDA) receptortarget
DB00686Pentosan PolysulfateFibroblast growth factor 1target
DB00686Pentosan PolysulfateFibroblast growth factor 4target
DB00686Pentosan PolysulfateFibroblast growth factor 2target
DB00815Sodium lauryl sulfateSerum albumincarrier
DB01008BusulfanCytochrome P450 3A4enzyme
DB01008BusulfanGlutathione S-transferase A2enzyme
DB01008BusulfanGlutathione S-transferase A1enzyme
DB01008BusulfanGlutathione S-transferase Mu 1enzyme
DB01008BusulfanGlutathione S-transferase Penzyme
DB01008BusulfanMicrosomal glutathione S-transferase 2enzyme
DB03120Para-Toluene SulfonateLysozyme Ctarget
DB03120Para-Toluene SulfonatePro-cathepsin Htarget
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerase, glycosomaltarget
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerasetarget
DB03309N-CyclohexyltaurineSulfotransferase family cytosolic 2B member 1target
DB03309N-CyclohexyltaurineNitrite reductasetarget
DB03309N-CyclohexyltaurineHomeobox protein engrailed-2target
DB03309N-CyclohexyltaurineRibonuclease PHtarget
DB03635Ethanesulfonic AcidPlatelet basic proteintarget
DB03635Ethanesulfonic AcidPhosphonoacetaldehyde hydrolasetarget
DB03967Dodecyl sulfateLysozyme Ctarget
DB03967Dodecyl sulfateLipid A palmitoyltransferase PagPtarget
DB04348Taurocholic AcidBile salt-activated lipasetarget
DB04348Taurocholic AcidGastrotropintarget
DB04348Taurocholic AcidBile salt export pumptransporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB04348Taurocholic AcidIleal sodium/bile acid cotransportertransporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B1transporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 2transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 4transporter
DB04348Taurocholic AcidMultidrug resistance protein 1transporter
DB04348Taurocholic AcidSolute carrier family 22 member 6transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 7transporter
DB04348Taurocholic AcidSolute carrier family 22 member 8transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 4A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family C member 11transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1C1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 3A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family G member 2transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 2B1transporter
DB04348Taurocholic AcidMonocarboxylate transporter 1transporter
DB04348Taurocholic AcidSodium/bile acid cotransportertransporter
DB04348Taurocholic AcidOrganic solute transporter subunit alphatransporter
DB04348Taurocholic AcidOrganic solute transporter subunit betatransporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B3transporter
DB04348Taurocholic AcidCystine/glutamate transportertransporter
DB04348Taurocholic AcidBile acid receptortarget
DB04640Naphthalene-2,6-disulfonic acidL-lactate dehydrogenasetarget
DB04640Naphthalene-2,6-disulfonic acidBacterioferritin comigratory proteintarget
DB04786SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB04786SuraminComplement control protein C3target
DB04786SuraminPhospholipase A2, membrane associatedtarget
DB04786SuraminP2Y purinoceptor 2target
DB04786SuraminFollicle-stimulating hormone receptortarget
DB04786SuraminRyanodine receptor 1target
DB04786SuraminArylsulfatase Aenzyme
DB04786SuraminCytosolic phospholipase A2enzyme
DB06231CaldaretSodium/calcium exchanger 1target
DB06442AvasimibeLiver carboxylesterase 1target
DB06442AvasimibeCytochrome P450 3A4enzyme
DB06442AvasimibeCytochrome P450 2C9enzyme
DB06442AvasimibeCytochrome P450 1A2enzyme
DB06442AvasimibeCytochrome P450 2C19enzyme
DB06536TesaglitazarPeroxisome proliferator-activated receptor alphatarget
DB06536TesaglitazarPeroxisome proliferator-activated receptor gammatarget
DB06757ManganeseCytoplasmic aconitate hydrataseenzyme
DB06757ManganeseIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
DB06757ManganeseIsocitrate dehydrogenase [NAD] subunit gamma, mitochondrialtarget
DB06757ManganeseTGF-beta-activated kinase 1 and MAP3K7-binding protein 1target
DB06778Cupric sulfateSerum albumintransporter
DB06778Cupric sulfateCeruloplasmintransporter
DB06778Cupric sulfatePhenylalanine-4-hydroxylaseenzyme
DB06778Cupric sulfateSuperoxide dismutase [Cu-Zn]enzyme
DB06778Cupric sulfateMonoamine oxidaseenzyme
DB06778Cupric sulfateProtein-lysine 6-oxidaseenzyme
DB06778Cupric sulfateCytochrome c oxidase subunit 1enzyme
DB06778Cupric sulfateTyrosinaseenzyme
DB08834Tauroursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
DB08834Tauroursodeoxycholic acidCystine/glutamate transportertransporter
DB08834Tauroursodeoxycholic acidCytochrome P450 3A1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 3A2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2A1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2A2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B9enzyme
DB09087Potassium alumSerum albumincarrier
DB09110Coenzyme MGlutathione reductase, mitochondrialenzyme
DB09322Zinc sulfateAlkaline phosphatase, placental-likeenzyme
DB09472Sodium sulfateCarbonic anhydrase 2target
DB09472Sodium sulfateCarbonic anhydrase 1target
DB09499Thiosulfuric acidThiosulfate sulfurtransferaseenzyme
DB14499Potassium sulfateSodium/potassium-transporting ATPase subunit alpha-1target
DB01956TaurineAlpha-ketoglutarate-dependent taurine dioxygenasetarget
DB01956TaurineCholoylglycine hydrolasetarget
DB01956TaurineGlycine receptor subunit alpha-1target
DB01956TaurineProton-coupled amino acid transporter 1transporter
DB01956TaurineSodium- and chloride-dependent taurine transportertransporter
DB01956TaurineSolute carrier family 15 member 1transporter
DB01956TaurineProtein-glutamine gamma-glutamyltransferase 6enzyme
DB01956TaurineBile acid-CoA:amino acid N-acyltransferaseenzyme
DB01956TaurineGlutamate receptor ionotropic, NMDA 2Btarget
DB01956TaurineGlycine receptor subunit alpha-2target
DB01956TaurineGlycine receptor subunit alpha-3target
DB01956TaurineGABA-A receptor (anion channel)target
DB01956TaurineGamma-aminobutyric acid type B receptor subunit 1target
DB02292IrosustatCarbonic anhydrase 2target
DB03848Benzenesulfinic acidOxysterols receptor LXR-betatarget