Deficiencies in enzymes of the urea cycle
Also known as: Urea cycle enzyme deficiency / Disorders of urea cycle metabolism / Disorder of urea cycle metabolism, unspecified / Urea cycle disorder / Urea Cycle Disorders, Inborn / Disorder of the urea cycle metabolism (disorder)
Drug | Drug Name | Drug Description |
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DB13207 | Arginine glutamate | Two amino acids indicated in the treatment of hyperammonemia and in combination for total parenteral nutrition. |
DB09269 | Phenylacetic acid | An agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. |
DB06819 | Phenylbutyric acid | An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. |
Drug | Drug Name | Target | Type |
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DB09269 | Phenylacetic acid | Liver carboxylesterase 1 | enzyme |
DB06819 | Phenylbutyric acid | Aromatic-amino-acid aminotransferase | target |
DB06819 | Phenylbutyric acid | Histone deacetylase | target |
Drug | Drug Name | Phase | Status | Count |
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