Severe Acne

Drug	Drug Name	Drug Description
DB04839	Cyproterone acetate	A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
DB00254	Doxycycline	A tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB00759	Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.

Drug	Drug Name	Target	Type
DB04839	Cyproterone acetate	Androgen receptor	target
DB04839	Cyproterone acetate	Prostate-specific antigen	target
DB04839	Cyproterone acetate	Cytochrome P450 3A4	enzyme
DB04839	Cyproterone acetate	Cytochrome P450 19A1	enzyme
DB00254	Doxycycline	Solute carrier family 22 member 6	transporter
DB00254	Doxycycline	Cytochrome P450 3A4	enzyme
DB00254	Doxycycline	ATP-binding cassette sub-family B member 5	transporter
DB00254	Doxycycline	Serum albumin	carrier
DB00254	Doxycycline	30S ribosomal protein	target
DB00759	Tetracycline	16S ribosomal RNA	target
DB00759	Tetracycline	Major prion protein	target
DB00759	Tetracycline	Serum albumin	carrier
DB00759	Tetracycline	Cytochrome P450 3A4	enzyme
DB00759	Tetracycline	Solute carrier family 22 member 6	transporter
DB00759	Tetracycline	Solute carrier family 22 member 8	transporter
DB00759	Tetracycline	Solute carrier family 22 member 11	transporter
DB00759	Tetracycline	Solute carrier family 22 member 7	transporter
DB00759	Tetracycline	30S ribosomal protein S3	target
DB00759	Tetracycline	30S ribosomal protein S8	target
DB00759	Tetracycline	30S ribosomal protein S19	target
DB00759	Tetracycline	30S ribosomal protein S14	target
DB00759	Tetracycline	30S ribosomal protein S7	target
DB00759	Tetracycline	Multidrug translocase MdfA	target
DB00759	Tetracycline	Protein-arginine deiminase type-4	target
DB00759	Tetracycline	Solute carrier organic anion transporter family member 2B1	transporter

Drug	Drug Name	Phase	Status	Count