Elevated Risk of Developing Breast Cancer

Also known as: Increased Risk for Development of Breast Cancer / High Risk for Developing Breast Cancer / High Risk of Breast Cancer / High Risk for Breast Cancer / High-Risk Breast Cancer

DrugDrug NameDrug Description
DB09074OlaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
DB00481RaloxifeneA selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women.
DrugDrug NameTargetType
DB09074OlaparibPoly [ADP-ribose] polymerase 1target
DB09074OlaparibCytochrome P450 3A4enzyme
DB09074OlaparibCytochrome P450 2B6enzyme
DB09074OlaparibPoly [ADP-ribose] polymerase 2target
DB09074OlaparibPoly [ADP-ribose] polymerase 3target
DB09074OlaparibCytochrome P450 3A5enzyme
DB09074OlaparibP-glycoprotein 1transporter
DB09074OlaparibATP-binding cassette sub-family G member 2transporter
DB09074OlaparibAldo-keto reductase family 1 member C3target
DB09074OlaparibUDP-glucuronosyltransferase 1-1enzyme
DB09074OlaparibSerum albumincarrier
DB09074OlaparibAlpha-1-acid glycoprotein 1carrier
DB00481RaloxifeneEstrogen receptor alphatarget
DB00481RaloxifeneEstrogen receptor betatarget
DB00481RaloxifeneAldehyde oxidaseenzyme
DB00481RaloxifeneCytochrome P450 2C8enzyme
DB00481RaloxifeneCytochrome P450 2B6enzyme
DB00481RaloxifeneCytochrome P450 19A1enzyme
DB00481RaloxifeneCytochrome P450 3A4enzyme
DB00481RaloxifeneSerpin B9target
DB00481RaloxifeneTrefoil factor 1target
DB00481RaloxifeneUDP-glucuronosyltransferase 1-1enzyme
DB00481RaloxifeneSerum albumincarrier
DB00481RaloxifeneAlpha-1-acid glycoprotein 1carrier
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B1transporter
DB00481RaloxifeneSolute carrier organic anion transporter family member 1B3transporter
DB00481RaloxifeneP-glycoprotein 1transporter
DB00481RaloxifeneATP-binding cassette sub-family G member 2transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 1transporter
DB00481RaloxifeneCanalicular multispecific organic anion transporter 2transporter
DB00481RaloxifeneMultidrug resistance-associated protein 4transporter
DB00481RaloxifeneUDP-glucuronosyltransferase 1-10enzyme
DB00481RaloxifeneUDP-glucuronosyltransferase 1-8enzyme
DrugDrug NamePhaseStatusCount
DB06401Bazedoxifene0Active Not Recruiting1
DB00286Conjugated estrogens0Active Not Recruiting1