Reaction: Acetaminophen to 1 product

Reaction
Reaction type
oxidation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Mazaleuskaya LL, Sangkuhl K, Thorn CF, FitzGerald GA, Altman RB, Klein TE: PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses. Pharmacogenet Genomics. 2015 Aug;25(8):416-26. doi: 10.1097/FPC.0000000000000150. [PubMed:26049587]
  2. FDA label [File]
  3. Acetaminophen data sheet, ebi.ac.uk [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2E1Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2D6Not AvailableNot Availableimplied
Cytochrome P450 2A6Not AvailableNot Availableimplied