Reaction: Diphenhydramine to 1 product

Reaction
Reaction type
N-demethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2C9Not AvailableNot Availableconfirmed
Cytochrome P450 2C19Not AvailableNot Availableconfirmed
Cytochrome P450 1A2Not AvailableNot Availableconfirmed
Cytochrome P450 2D6Not AvailableNot Availableconfirmed